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The Future of Antibiotics and Resistance: A Tribute to a Career of Leadership by John Bartlett
Open accessAbstract
The ways we have developed, used, and protected antibiotics have led, predictably, to our current crisis of rising antibiotic resistance and declining new treatments. If we want to stave off a postantibiotic era, we need to fundamentally change our approach. We need to challenge long-standing assumptions and cherished beliefs. We need to push through the reflexive resistance and excuses (eg, "that's not how we do things" and "that can't be done") that result from challenging established ways. Excuses abound. Action is needed. Ultimately, we need a coordinated national action plan to combat resistance. Herein we discuss 7 tasks and 3 common themes that cut across those tasks, which are necessary to achieve long-term success in dealing with antibiotics and resistance. These principles derive from many years of dialogue with Dr John Bartlett. The field of infectious diseases, and indeed medicine in general, has benefited immeasurably from his remarkable leadership.
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Citations
Cited by
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Rossiter, S. E., Fletcher, M. H., & Wuest, W. M. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00283 · Cited by 622
The recent progress of isoxazole in medicinal chemistry
Zhu, J., Mo, J., Lin, H.-Z., Chen, Y., & Sun, H.-P. (2018) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2018.05.013 · Cited by 417
Godman, B., Haque, M., McKimm, J., Abu Bakar, M., Sneddon, J., Wale, J., Campbell, S., Martin, A. P., Hoxha, I., Abilova, V., et al. (2020) · Current Medical Research and Opinion · doi:10.1080/03007995.2019.1700947 · Cited by 171
Lima, P. G., Oliveira, J. T. A., Amaral, J. L., Freitas, C. D. T., & Souza, P. F. N. (2021) · Life Sciences · doi:10.1016/j.lfs.2021.119647 · Cited by 170
Metadata
- Authors
- Spellberg, B., & Gilbert, D. N.
- Venue
- Clinical Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2014-08-23
- Volume
- 59
- Issue
- suppl 2
- Pages
- S71-S75
- ISSN
- 1058-4838 (ISSN-L)
- 1537-6591
- OpenAlex
- W2043000592
- Cited by
- 324
- References
- 0
- FWCI
- 8.42
- Type
- journal article
- Language
- en
- Open access
- bronze
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