The DOI matches its Crossref record.
Reduced Susceptibility to Vancomycin Influences Pathogenicity in Staphylococcus aureus Infection
Open accessAbstract
In the present study, we demonstrated the utility of the nonmammalian model system Galleria mellonella for studying the pathogenesis of Staphylococcus aureus infection. By use of clinical and laboratory strains that had been exposed to vancomycin, we showed that both agr functional status and vancomycin minimum inhibitory concentration are determinants associated with the virulence of S. aureus in G. mellonella. These results show that G. mellonella can be effectively used to facilitate the in vivo study of S. aureus virulence and, more specifically, the relationship between antibiotic drug resistance and the pathogenesis of infection.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Howden, B. P., Davies, J. K., Johnson, P. D. R., Stinear, T. P., & Grayson, M. L. (2010) · Clinical Microbiology Reviews · doi:10.1128/cmr.00042-09 · Cited by 962
Mechanisms of vancomycin resistance in Staphylococcus aureus
Gardete, S., & Tomasz, A. (2014) · Journal of Clinical Investigation · doi:10.1172/jci68834 · Cited by 565
The Insect Galleria mellonella as a Powerful Infection Model to Investigate Bacterial Pathogenesis
Ramarao, N., Nielsen-Leroux, C., & Lereclus, D. (2012) · Journal of Visualized Experiments · doi:10.3791/4392 · Cited by 277
Moellering, R. C. (2012) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkr437 · Cited by 236
Self-citationPathogenicity of Aspergillus fumigatus mutants assessed in Galleria mellonella matches that in mice
Slater, J. L., Gregson, L., Denning, D. W., & Warn, P. A. (2011) · Medical Mycology · doi:10.3109/13693786.2010.523852 · Cited by 136
Metadata
- Authors
- Peleg, A. Y., Monga, D., Pillai, S., Mylonakis, E., Moellering, Jr., & Eliopoulos, G. M.
- Venue
- The Journal of Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2009-02-15
- Volume
- 199
- Issue
- 4
- Pages
- 532-536
- ISSN
- 0022-1899 (ISSN-L)
- 1537-6613
- OpenAlex
- W2149023722
- Cited by
- 162
- References
- 0
- FWCI
- 8.59
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Reduced Susceptibility to Vancomycin Influences Pathogenicity in Staphylococcus aureus Infection. https://app.cochat.ai/papers/10.1086/596511
- The paper
- Peleg, A. Y., Monga, D., Pillai, S., Mylonakis, E., Moellering, Jr., & Eliopoulos, G. M. (2009). Reduced Susceptibility to Vancomycin Influences Pathogenicity in Staphylococcus aureus Infection. The Journal of Infectious Diseases. https://doi.org/10.1086/596511
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
