The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Progress and Challenges in Implementing the Research on ESKAPE Pathogens
Abstract
The ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species) are responsible for a substantial percentage of nosocomial infections in the modern hospital and represent the vast majority of isolates whose resistance to antimicrobial agents presents serious therapeutic dilemmas for physicians. Over the years, improved molecular biology techniques have led to detailed information about individual resistance mechanisms in all these pathogens. However, there remains a lack of compelling data on the interplay between resistance mechanisms and between the bacteria themselves. In addition, data on the impact of clinical interventions to decrease the prevalence of resistance are also lacking. The difficulty in identifying novel antimicrobial agents with reliable activity against these pathogens argues for an augmentation of research in the basic and population science of resistance, as well as careful studies to identify optimal strategies for infection control and antimicrobial use.
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Cites
An Intervention to Decrease Catheter-Related Bloodstream Infections in the ICU
Pronovost, P., Needham, D., Berenholtz, S., Sinopoli, D., Chu, H., Cosgrove, S., Sexton, B., Hyzy, R., Welsh, R., Roth, G., et al. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa061115 · Cited by 4,387
Molecular Basis of Bacterial Outer Membrane Permeability Revisited
Nikaido, H. (2003) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.67.4.593-656.2003 · Cited by 4,316
Hidron, A. I., Edwards, J. R., Patel, J., Horan, T. C., Sievert, D. M., Pollock, D. A., Fridkin, S. K., & National Healthcare Safety Network Team and Participating National Healthcare Safety Network Facilities (2008) · Infection Control & Hospital Epidemiology · doi:10.1086/591861 · Cited by 3,724
Cited by
Mechanisms of Antimicrobial Resistance in ESKAPE Pathogens
Santajit, S., & Indrawattana, N. (2016) · BioMed Research International · doi:10.1155/2016/2475067 · Cited by 1,641
Antibiotic resistance and persistence—implications for human health and treatment perspectives
Huemer, M., Mairpady Shambat, S., Brugger, S. D., & Zinkernagel, A. S. (2020) · The EMBO Reports · doi:10.15252/embr.202051034 · Cited by 850
Davin-Regli, A., & Pagès, J.-M. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.00392 · Cited by 627
Novel classes of antibiotics or more of the same?
Coates, A. R., Halls, G., & Hu, Y. (2011) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2011.01250.x · Cited by 598
Zhanel, G. G., Chung, P., Adam, H., Zelenitsky, S., Denisuik, A., Schweizer, F., Lagacé-Wiens, P. R. S., Rubinstein, E., Gin, A. S., Walkty, A., et al. (2014) · Drugs · doi:10.1007/s40265-013-0168-2 · Cited by 340
Metadata
- Authors
- Rice, L. B.
- Venue
- Infection Control & Hospital Epidemiology
- Publisher
- Cambridge University Press (CUP)
- Published
- 2010-11
- Volume
- 31
- Issue
- S1
- Pages
- S7-S10
- ISSN
- 0899-823X (ISSN-L)
- 1559-6834
- OpenAlex
- W2201379139
- Cited by
- 370
- References
- 3
- FWCI
- 3.49
- Type
- journal article
- Language
- en
- Open access
- closed
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