The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.
Diamond for bio-sensor applications
Open accessAbstract
A summary of photo- and electrochemical surface modifications applied on single-crystalline chemical vapour deposition (CVD) diamond films is given. The covalently bonded formation of amine- and phenyl-linker molecule layers is characterized using x-ray photoelectron spectroscopy, atomic force microscopy (AFM), cyclic voltammetry and field-effect transistor characterization experiments. Amine- and phenyl-layers are very different with respect to formation, growth, thickness and molecule arrangement. We detect a single-molecular layer of amine-linker molecules on diamond with a density of about 10 14 cm −2 (10% of carbon bonds). Amine molecules are bonded only on initially H-terminated surface areas to carbon. In the case of electrochemical deposition of phenyl-layers, multi-layer formation is detected due to three-dimensional (3D) growths. This gives rise to the formation of typically 25 Å thick layers. The electrochemical grafting of boron-doped diamond works on H-terminated and oxidized surfaces. After reacting such films with hetero-bifunctional crosslinker molecules, thiol-modified ss-DNA markers are bonded to the organic system. Application of fluorescence and AFM on hybridized DNA films shows dense arrangements with densities of up to 10 13 cm −2 . The DNA is tilted by an angle of about 35° with respect to the diamond surface. Shortening the bonding time of thiol-modified ss-DNA to 10 min causes a decrease of DNA density to about 10 12 cm −2 . Application of AFM scratching experiments shows threshold removal forces of around 75 nN for DNA bonded on phenyl-linker molecules and of about 45 nN for DNA bonded to amine-linker molecules. DNA sensor applications using Fe(CN 6 ) 3−/4− mediator redox molecules, impedance spectroscopy and DNA-field effect transistor devices performances are introduced and discussed.
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Cites
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Nanodiamond Particles: Properties and Perspectives for Bioapplications
Schrand, A. M., Hens, S. A. C., & Shenderova, O. A. (2009) · Critical Reviews in Solid State and Materials Sciences · doi:10.1080/10408430902831987 · Cited by 802
Activation of Persulfates by Graphitized Nanodiamonds for Removal of Organic Compounds
Lee, H., Kim, H.-I., Weon, S., Choi, W., Hwang, Y. S., Seo, J., Lee, C., & Kim, J.-H. (2016) · Environmental Science & Technology · doi:10.1021/acs.est.6b02079 · Cited by 688
Nanocarbons for Biology and Medicine: Sensing, Imaging, and Drug Delivery
Panwar, N., Soehartono, A. M., Chan, K. K., Zeng, S., Xu, G., Qu, J., Coquet, P., Yong, K.-T., & Chen, X. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.9b00099 · Cited by 555
Conductive diamond: synthesis, properties, and electrochemical applications
Yang, N., Yu, S., Macpherson, J. V., Einaga, Y., Zhao, H., Zhao, G., Swain, G. M., & Jiang, X. (2019) · Chemical Society Reviews · doi:10.1039/c7cs00757d · Cited by 522
Self-citation
Metadata
- Authors
- Nebel, C. E., Rezek, B., Shin, D., Uetsuka, H., & Yang, N.
- Venue
- Journal of Physics D: Applied Physics
- Publisher
- IOP Publishing
- Published
- 2007-10-05
- Volume
- 40
- Issue
- 20
- Pages
- 6443-6466
- ISSN
- 0022-3727 (ISSN-L)
- 1361-6463
- OpenAlex
- W1963521342
- Cited by
- 253
- References
- 33
- FWCI
- 9.51
- Type
- journal article
- Language
- en
- Open access
- green
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- Nebel, C. E., Rezek, B., Shin, D., Uetsuka, H., & Yang, N. (2007). Diamond for bio-sensor applications. Journal of Physics D: Applied Physics. https://doi.org/10.1088/0022-3727/40/20/s21
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