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The theoretical basis for the determination of optical pathlengths in tissue: temporal and frequency analysis

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Arridge, S R, Cope, M, Delpy, D T·1992·Physics in Medicine and Biology

Abstract

A concise theoretical treatment is developed for the calculation of mean time, differential pathlength, phase shift, modulation depth and integrated intensity of measurements of light intensity as a function of time on the surface of tissue, resulting from either the input of picosecond light pulses, or radio frequency-modulated light. The treatment uses the Green's function of the diffusion approximation to the radiative transfer equation, and develops this and its Fourier transform in a variety of geometries. Detailed comparisons are made of several of these parameters in several geometries, and their relation to experimentally measured clinical data. The limitations of the use of phase measurements is discussed.

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Metadata

Authors
Arridge, S. R., Cope, M., & Delpy, D. T.
Venue
Physics in Medicine and Biology
Published
1992-07-01
Volume
37
Issue
7
Pages
1531-1560
ISSN
  • 0031-9155 (ISSN-L)
  • 1361-6560
OpenAlex
W2020528079
Cited by
595
References
0
FWCI
15.14
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: The theoretical basis for the determination of optical pathlengths in tissue: temporal and frequency analysis. https://app.cochat.ai/papers/10.1088/0031-9155/37/7/005
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Arridge, S. R., Cope, M., & Delpy, D. T. (1992). The theoretical basis for the determination of optical pathlengths in tissue: temporal and frequency analysis. Physics in Medicine and Biology. https://doi.org/10.1088/0031-9155/37/7/005

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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.