Cited by 243Advanced Radiotherapy TechniquesMedical Image Segmentation TechniquesRadiation Dose and Imaging

The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.

Implementation and evaluation of various demons deformable image registration algorithms on a GPU

Open access

Abstract

Online adaptive radiation therapy (ART) promises the ability to deliver an optimal treatment in response to daily patient anatomic variation. A major technical barrier for the clinical implementation of online ART is the requirement of rapid image segmentation. Deformable image registration (DIR) has been used as an automated segmentation method to transfer tumor/organ contours from the planning image to daily images. However, the current computational time of DIR is insufficient for online ART. In this work, this issue is addressed by using computer graphics processing units (GPUs). A gray-scale-based DIR algorithm called demons and five of its variants were implemented on GPUs using the compute unified device architecture (CUDA) programming environment. The spatial accuracy of these algorithms was evaluated over five sets of pulmonary 4D CT images with an average size of 256 x 256 x 100 and more than 1100 expert-determined landmark point pairs each. For all the testing scenarios presented in this paper, the GPU-based DIR computation required around 7 to 11 s to yield an average 3D error ranging from 1.5 to 1.8 mm. It is interesting to find out that the original passive force demons algorithms outperform subsequently proposed variants based on the combination of accuracy, efficiency and ease of implementation.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1088/0031-9155/55/1/012

Cites

33 of 33 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Research works printed but not linked: 4

  1. Jacques R Taylor R Wong J McNutt T, 2008, High-Performance Medical Image Computing and Computer Aided Intervention Workshop
  2. Li M, 2007, Med. Imaging Technol., 25, 243
  3. Pennec X Cachier P Ayache N Taylor C Colchester A, 1999, Proc. 2nd Int. Conf. on Medical Image Computing and Computer-Assisted Intervention-MICCAI'99, 597
  4. Riabkov D, 2008, Proc. SPIE, 69132, V1

Cited by

Sorted by citations

See all 243

Metadata

Authors
Gu, X., Pan, H., Liang, Y., Castillo, R., Yang, D., Choi, D., Castillo, E., Majumdar, A., Guerrero, T., & Jiang, S. B.
Affiliations
  • University of California San Diego (US)
  • The University of Texas MD Anderson Cancer Center (US)
  • Washington University in St. Louis (US)
  • San Diego Supercomputer Center (US)
Venue
Physics in Medicine and Biology
Published
2009-12-11
Volume
55
Issue
1
Pages
207-219
ISSN
  • 0031-9155 (ISSN-L)
  • 1361-6560
OpenAlex
W2133277680
Cited by
243
References
33
Citations by year
2026: 2 · 2025: 6 · 2024: 2 · 2023: 5 · 2022: 7 · 2021: 8 · 2020: 12 · 2019: 13 · 2018: 13 · 2017: 12 · 2016: 17 · 2015: 29 · 2014: 22 · 2013: 35 · 2012: 20
FWCI
19.05
Type
journal article
Language
en
Open access
Locations
  • Physics in Medicine and Biology (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
  • arXiv (Cornell University) (submittedVersion)
  • arXiv (Cornell University)
Funders
  • Nvidia
  • National Institutes of Health
  • National Cancer Institute (F32CA154045, R21CA141833, R21CA128230, T32CA119930)
Topics
  • Physical Sciences › Physics and Astronomy › Radiation › Advanced Radiotherapy Techniques
  • Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Medical Image Segmentation Techniques
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Radiation Dose and Imaging
Keywords
deformable image registration, Demons algorithm, GPU acceleration, online adaptive radiotherapy, image segmentation, 4D-CT, lung CT, CUDA
MeSH terms
Algorithms, Computer Graphics, Humans, Image Processing, Computer-Assisted, Lung, Time Factors, Tomography, X-Ray Computed, Databases as Topic, Imaging, Three-Dimensional

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review