Evaluation of blood pressure changes using vascular transit time
Open accessAbstract
Imbalance of the human haemodynamic system can provide a prognosis of syncope, dizziness or hypertension. This can be assessed by monitoring its responses to postural change. Examining variations in blood pressure (BP) is deemed an effective means to identify symptoms of this associated condition. However, conventional methods do not promote prolonged monitoring due to the discomfort caused to patients. Established correlations between BP and pulse wave transmission have shown its usefulness in clinical applications. In this study, photoplethysmography and phonocardiography were used to estimate BP changes via observed variations in delay transmission or vascular transit time (VTT) at the upper limb. Thirty-one healthy adults (21 male) were recruited to perform three test activities, namely the arm held at heart level, fully raised up and held down. Association of the three BP indices and heart rate variations with transit time changes was then computed. The results showed that observed VTT changes were related to systolic BP (R(2) = 0.820; p < 0.05), diastolic BP (R(2) = 0.517; p < 0.05), mean arterial pressure (R(2) = 0.673; p < 0.05) and heart rate (R(2) = 0.000; p > 0.05). As systolic BP had the strongest correlation, a regression equation was formulated to associate the two parameters. The non-invasive measuring nature of VTT can be more accommodating to patients, especially during continual monitoring. Moreover, it has the added advantage that the pre-ejection period is not included in its time-related derivations.
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FDA guidelines for RR monitors under 21 CFR 870.2375 do not specify accuracy requirements, but a 510(k) cleared bedside monitoring system (Siemens SC 6000) delivers a target accuracy of ±3 breaths per minute.
“FDA guidelines for RR monitors under 21 CFR 870.2375 does not specify requirements in terms of accuracy28, but a 510(k) cleared bedside monitoring system (Siemens SC 6000) delivers a target accuracy of ± 3 breath per minute.”
From Skin-interfaced biosensors for advanced wireless physiological monitoring in neonatal and pediatric intensive-care units (2020) · cites this paper as [28]
The Introduction and Experimental protocol discuss blood-pressure monitoring and the instruments used to measure it, not respiratory-rate monitor requirements. Searches for 21 CFR 870.2375, FDA accuracy requirements, Siemens SC 6000, and ±3 breaths per minute found no passage addressing the claim. (LLM, conf=0.76)
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References 33 · Cited by 62
- Authors
- Foo, J. Y. A., Lim, C. S., & Wang, P.
- Affiliations
- Nanyang Technological University (SG)
- Venue
- Physiological Measurement
- Publisher
- IOP Publishing
- Published
- 2006-05-26
- Volume
- 27
- Issue
- 8
- Pages
- 685-694
- ISSN
- 0967-3334 (ISSN-L)
- 1361-6579
- OpenAlex
- W2031137127
- Cited by
- 62
- References
- 33
- Citations by year
- 2024: 3 · 2023: 3 · 2022: 4 · 2021: 8 · 2020: 7 · 2019: 3 · 2018: 1 · 2017: 7 · 2016: 2 · 2015: 4 · 2013: 4 · 2012: 3
- FWCI
- 2.05
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Physiological Measurement (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Health Sciences › Medicine › Surgery › Hemodynamic Monitoring and Therapy
- Keywords
- blood pressure estimation, photoplethysmography, phonocardiography, postural changes, arm position, systolic blood pressure, non-invasive blood pressure monitoring, hemodynamic monitoring, syncope, dizziness, hypertension
- MeSH terms
- Adult, Blood Pressure, Blood Pressure Determination, Female, Heart Rate, Humans, Male, Phonocardiography, Time, Photoplethysmography
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