Positive Provider Interactions, Adherence Self-Efficacy, and Adherence to Antiretroviral Medications Among HIV-Infected Adults: A Mediation Model
Open accessAbstract
Adherence to antiretroviral (ARV) therapy for HIV infection is critical for maximum benefit from treatment and for the prevention of HIV-related complications. There is evidence that many factors determine medication adherence, including adherence self-efficacy (confidence in one's ability to adhere) and relations with health care providers. However, there are no studies that examine how these two factors relate to each other and their subsequent influence on HIV medication adherence. The goal of the current analysis was to explore a model of medication adherence in which the relationship between positive provider interactions and adherence is mediated by adherence self-efficacy. Computerized self-administered and interviewer-administered self reported measures of medication adherence, demographic and treatment variables, provider interactions, and adherence self-efficacy were administered to 2765 HIV-infected adults on ARV. Criteria for mediation were met, supporting a model in which adherence self-efficacy is the mechanism for the relationship between positive provider interactions and adherence. The finding was consistent when the sample was stratified by gender, race, injection drug use history, and whether the participant reported receipt of HIV specialty care. Positive provider interactions may foster greater adherence self-efficacy, which is associated with better adherence to medications. Results suggest implications for improving provider interactions in clinical care, and future directions for clarifying interrelationships among provider interactions, adherence self-efficacy, and medication adherence are supported.
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Confidence in one's ability to pursue goals affects how well people adhere to medication across many long-term illnesses.
“Self-efficacy or confidence in one’s ability to successfully engage in goal-directed behavior has been shown to influence medication adherence across many chronic illnesses.”
From Reliability and validity of a self‐efficacy instrument for hepatitis C antiviral treatment regimens (2012) · cites this paper as [18]
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Reliability and validity of a self‐efficacy instrument for hepatitis C antiviral treatment regimens
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- Authors
- Johnson, M. O., Chesney, M. A., Goldstein, R. B., Remien, R. H., Catz, S., Gore-Felton, C., Charlebois, E., Morin, S. F., & NIMH Healthy Living Project Team
- Affiliations
- University of California, San Francisco (US)
- Center for Community Health, University of California, Los Angeles, Los Angeles, California.
- New York State Psychiatric Institute (US)
- Group Health Cooperative (US)
- Medical College of Wisconsin (US)
- Venue
- AIDS Patient Care and STDs
- Publisher
- SAGE Publications
- Published
- 2006-04
- Volume
- 20
- Issue
- 4
- Pages
- 258-268
- ISSN
- 1087-2914 (ISSN-L)
- 1557-7449
- PMC
- PMC2432422
- OpenAlex
- W1988785595
- Cited by
- 170
- References
- 50
- Citations by year
- 2026: 1 · 2024: 5 · 2023: 4 · 2022: 5 · 2021: 7 · 2020: 5 · 2019: 8 · 2018: 7 · 2017: 7 · 2016: 15 · 2015: 18 · 2014: 8 · 2013: 16 · 2012: 12
- FWCI
- 6.16
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- AIDS Patient Care and STDs (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (P30-MH43520, P30 MH57226, K08-MH01995, U10MH057615, U10MH057636, U10MH057616, U10 MH 57615, K08MH001995, U10-MH57616, U10MH057631, U10- MH57631, U10-MH57636, P30MH058107, P30MH062246, P30MH043520)
- Topics
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Health Sciences › Medicine › Epidemiology › HIV, Drug Use, Sexual Risk
- Keywords
- HIV, antiretroviral therapy, medication adherence, adherence self-efficacy, provider-patient interaction, mediation model, intravenous drug use, gender differences, racial differences
- MeSH terms
- Adult, Communication, Female, Health Personnel, Humans, Male, Middle Aged, Patient Compliance, Physician-Patient Relations, HIV Infections, Negotiating, Anti-HIV Agents, Self Efficacy
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