NOX2 and NOX4 Mediate Proliferative Response in Endothelial Cells

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Items 101–200 of 242

  1. Nox4 overexpression activates reactive oxygen species and p38 MAPK in human endothelial cells
    Claudia Goettsch, Winfried Göettsch, Gregor M. Müller, Jochen Seebach, Hans‐Joachim Schnittler, Henning Morawietz · 2009 · Biochemical and Biophysical Research Communications
  2. The HIF1 target geneNOX2promotes angiogenesis through urotensin-II
    Isabel Diebold, Andreas Petry, Karim Sabrane, Talija Djordjevic, John Hess, Agnes Görlach · 2012 · Journal of Cell Science
  3. NADPH oxidase-derived ROS and the regulation of pulmonary vessel tone
    Giovanna Frazziano, Hunter C. Champion, Patrick J. Pagano · 2012 · American Journal of Physiology-Heart and Circulatory Physiology
  4. Lipopolysaccharide induced LOX-1 expression via TLR4/MyD88/ROS activated p38MAPK-NF-κB pathway
    Wenwen Zhao, Guixin Ma, Xiuping Chen · 2014 · Vascular Pharmacology
  5. Expression of NADPH oxidases and enhanced H2O2-generating activity in human coronary artery endothelial cells upon induction with tumor necrosis factor-α
    Yoshida, Lucia S., Tsunawaki, Shohko · 2008 · International Immunopharmacology
  6. Pharmacological strategies to lower crosstalk between nicotinamide adenine dinucleotide phosphate (NADPH) oxidase and mitochondria
    Nirmala Koju, Abdoh Taleb, Jifang Zhou, Lv Ge, Jie Yang, Xian Cao, Hui Lei, Qilong Ding · 2019 · Biomedicine & Pharmacotherapy
  7. Hydrogen peroxide derived from NADPH oxidase 4- and 2 contributes to the endothelium-dependent vasodilatation of intrarenal arteries
    Mercedes Muñoz, María Pilar Martínez, María Elvira López‐Oliva, Claudia Rodríguez, César Corbacho, Joaquı́n Carballido, Albino García‐Sacristán, Medardo Hernández, Luis Rivera, J. Sáenz Medina et al. · 2018 · Redox Biology
  8. Nox2 regulates endothelial cell cycle arrest and apoptosis via p21cip1 and p53
    Jian‐Mei Li, Lampson M. Fan, Vinoj T. George, Gavin Brooks · 2007 · Free Radical Biology and Medicine
  9. Regulation of Proliferation of Skeletal Muscle Precursor Cells By NADPH Oxidase
    Mahroo Mofarrahi, Ralf Peter Brandes, Agnes Görlach, Jörg Hänze, Lance S. Terada, Mark T. Quinn, Dominique Mayaki, Basil J. Petrof, Sabah N. A. Hussain · 2007 · Antioxidants and Redox Signaling
  10. Current status of NADPH oxidase research in cardiovascular pharmacology
    Ezequiel Álvarez, Rodiño-Janeiro, Paradela-Dobarro, Castiñeiras-Landeira, Sergio Raposeiras‐Roubín, José Ramón González‐Juanatey · 2013 · Vascular Health and Risk Management
  11. H2O2 Production Downstream of FLT3 Is Mediated by p22phox in the Endoplasmic Reticulum and Is Required for STAT5 Signalling
    John F. Woolley, Ruth Naughton, Joanna Stanicka, David R. Gough, Lavinia Bhatt, Bryan C. Dickinson, Christopher J. Chang, Thomas G. Cotter · 2012 · PLoS ONE
  12. Stress‐induced activation of Nox contributes to cell survival signalling via production of hydrogen peroxide
    Gillian Groeger, Ashley M. Mackey, Christopher A. Pettigrew, Lavinia Bhatt, Thomas G. Cotter · 2009 · Journal of Neurochemistry
  13. Role of extracellular DNA oxidative modification in radiation induced bystander effects in human endotheliocytes
    Svetlana V. Kostyuk, Aleksei V. Ermakov, Anna Yu. Alekseeva, Tatiana D. Smirnova, Kristina V. Glebova, Liudmila V. Efremova, Ancha V. Baranova, Н. Н. Вейко · 2011 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
  14. The NADPH Oxidase Complexes in Botrytis cinerea: Evidence for a Close Association with the ER and the Tetraspanin Pls1
    Ulrike Siegmund, Jens Heller, Jan A. L. van Kan, Paul Tudzynski · 2013 · PLoS ONE
  15. Involvement of NADPH oxidases in alkali burn-induced corneal injury
    XUE-JUN GU, Xian Liu, Yingying Chen, Yao Zhao, Man Xu, Xiao‐Jian Han, Qiuping Liu, Jinglin Yi, Jingming Li · 2016 · International Journal of Molecular Medicine
  16. NOX4 mediates activation of FoxO3a and matrix metalloproteinase-2 expression by urotensin-II
    Isabel Diebold, Andreas Petry, Maximilian Burger, John Hess, Agnes Görlach · 2011 · Molecular Biology of the Cell
  17. Transcriptional Regulation of Cystathionine-γ-Lyase in Endothelial Cells by NADPH Oxidase 4-Dependent Signaling
    Rajesh K. Mistry, Thomas V. Murray, Oleksandra D. Prysyazhna, Daniel Martin, Joseph Robert Burgoyne, Célio X.C. Santos, Philip Eaton, Ajay M. Shah, Alison C. Brewer · 2015 · Journal of Biological Chemistry
  18. NADPH Oxidase 4-Derived H 2 O 2 Promotes Aberrant Retinal Neovascularization via Activation of VEGF Receptor 2 Pathway in Oxygen-Induced Retinopathy
    Jingming Li, Joshua Jianxin Wang, Sarah Xin Zhang · 2015 · Journal of Diabetes Research
  19. NADPH Oxidases: New Regulators of Old Functions
    Kathy K. Griendling · 2006 · Antioxidants and Redox Signaling
  20. Ginsenoside Rb1 Attenuates High Glucose-Induced Oxidative Injury via the NAD-PARP-SIRT Axis in Rat Retinal Capillary Endothelial Cells
    Chunlan Fan, Qing Ma, Meng Qing Xu, Yuan Qiao, Yi Zhang, Pin Li, Yucong Bi, Minke Tang · 2019 · International Journal of Molecular Sciences
  21. Activation-dependent stabilization of the human thromboxane receptor: role of reactive oxygen species
    Stephen J. Wilson, Claire C. Cavanagh, Allison M. Lesher, Alexander J. Frey, Shane E. Russell, Emer M. Smyth · 2009 · Journal of Lipid Research
  22. Dihydrotanshinone I Attenuates Atherosclerosis in ApoE-Deficient Mice: Role of NOX4/NF-κB Mediated Lectin-Like Oxidized LDL Receptor-1 (LOX-1) of the Endothelium
    Wenwen Zhao, Chunxia Li, Hongwei Gao, Qin Wu, Jingshan Shi, Xiuping Chen · 2016 · Frontiers in Pharmacology
  23. Differential roles of NADPH oxidases in vascular physiology and pathophysiology
    Kathy K. Griendling · 2012 · Frontiers in Bioscience-Scholar
  24. Role of Reactive Oxygen Species in Neonatal Pulmonary Vascular Disease
    Stephen Wedgwood, Robin Heise Steinhorn · 2013 · Antioxidants and Redox Signaling
  25. NOX4: a potential therapeutic target for pancreatic cancer and its mechanism
    Ya‐Wei Bi, Xiao Lei, Ningli Chai, Enqiang Linghu · 2021 · Journal of Translational Medicine
  26. Translation-Linked mRNA Destabilization Accompanying Serum-Induced Nox4 Expression in Human Endothelial Cells
    Hitesh Peshavariya, Fan Jiang, Caroline J. Taylor, Stavros Selemidis, Catherine W.T. Chang, Gregory James Dusting · 2009 · Antioxidants and Redox Signaling
  27. Nox-4–Dependent Nuclear H 2 O 2 Drives DNA Oxidation Resulting in 8-OHdG as Urinary Biomarker and Hemangioendothelioma Formation
    Gayle M. Gordillo, Huiqing Fang, Hana Park, Sashwati Roy · 2009 · Antioxidants and Redox Signaling
  28. Inhibitory Effects of β-Caryophyllene on Helicobacter pylori Infection In Vitro and In Vivo
    Hyun Jun Woo, Ji Yeong Yang, Min Ho Lee, Hyun Woo Kim, Hye Jin Kwon, Min Park, Sung‐Kyu Kim, Soyoung Park, Jong‐Bae Kim, Jong‐Bae Kim · 2020 · International Journal of Molecular Sciences
  29. Isoform specific functions of Nox protein-derived reactive oxygen species in the vasculature
    Katrin Schröder · 2010 · Current Opinion in Pharmacology
  30. The NADPH oxidases NOX4 and DUOX2 regulate cell cycle entry via a p53-dependent pathway
    Annette E. Salmeen, B O Park, Tobias Meyer · 2010 · Oncogene
  31. Myofibroblast Differentiation: Main Features, Biomedical Relevance, and the Role of Reactive Oxygen Species
    Alessandro Siani, Nicola Tirelli · 2013 · Antioxidants and Redox Signaling
  32. SERPINA3K Protects against Oxidative Stress via Modulating ROS Generation/Degradation and KEAP1-NRF2 Pathway in the Corneal Epithelium
    Tong Zhou, Rongrong Zong, Zhoujing Zhang, Chengpeng Zhu, Fangyu Pan, Xinye Xiao, Zhen Liu, Hui He, Jian‐xing Ma, Zuguo Liu et al. · 2012 · Investigative Ophthalmology & Visual Science
  33. The regulation of cardiac intermediary metabolism by NADPH oxidases
    Adam Nabeebaccus, Christina Maria Reumiller, Jie Shen, Anna Zoccarato, Célio X.C. Santos, Ajay M. Shah · 2022 · Cardiovascular Research
  34. Apocynin improves oxygenation and increases eNOS in persistent pulmonary hypertension of the newborn
    Stephen Wedgwood, Satyan Lakshminrusimha, Kathryn N. Farrow, Lyubov Czech, Sylvia F. Gugino, Fernando Augusto Soares, James A. Russell, Robin Heise Steinhorn · 2011 · American Journal of Physiology-Lung Cellular and Molecular Physiology
  35. NADPH oxidases as electrochemical generators to produce ion fluxes and turgor in fungi, plants and humans
    Anthony Walter Segal · 2016 · Open Biology
  36. The role of NOX4 in pulmonary diseases
    Ziming Li, Sheng‐Ya Xu, Yi‐Zhuo Feng, Yu‐Rui Cheng, Jian‐Bing Xiong, Yong Zhou, Cha‐Xiang Guan · 2020 · Journal of Cellular Physiology
  37. Redox interactions-induced cardiac toxicity in cancer therapy
    Xiao Fu, Juan Tang, Ping Wen, Zezhi Huang, Masoud Najafi · 2021 · Archives of Biochemistry and Biophysics
  38. NADPH Oxidase Is Internalized by Clathrin-coated Pits and Localizes to a Rab27A/B GTPase-regulated Secretory Compartment in Activated Macrophages
    Patrick Ejlerskov, Dan Ploug Christensen, David Beyaie, James B. Burritt, Marie‐Hélène Paclet, Agnes Görlach, Bo van Deurs, Frederik Vilhardt · 2011 · Journal of Biological Chemistry
  39. Transcriptional Regulation of Serine/Threonine Kinase-15 (STK15) Expression by Hypoxia and HIF-1
    Alexandra M. Klein, Daniela Flügel, Thomas Kietzmann · 2008 · Molecular Biology of the Cell
  40. Long-Term Cyclic Strain Downregulates Endothelial Nox4
    Claudia Goettsch, Winfried Göettsch, Alexander Arsov, Lorenz Christian Hofbauer, Stefan Richard Bornstein, Henning Morawietz · 2009 · Antioxidants and Redox Signaling
  41. Inflammation and reactive oxygen species in cardiovascular disease
    Nannan Zhang · 2010 · World Journal of Cardiology
  42. Anthocyanins and Vascular Health: A Matter of Metabolites
    Joseph Festa, Aamir Hussain, Zakia Al-Hareth, Harprit Singh, Mariasole Da Boit · 2023 · Foods
  43. The NOX on Pulmonary Hypertension
    Karl A. Sanders, John R. Hoidal · 2007 · Circulation Research
  44. Oxidative and nitrosative stress during pulmonary ischemia-reperfusion injury: from the lab to the OR
    Jan F. Gielis, Paul A. J. Beckers, Jacob J. Briedé, Paul Cos, Paul E. Van Schil · 2017 · Annals of Translational Medicine
  45. Loss of USF2 promotes proliferation, migration and mitophagy in a redox-dependent manner
    Tabughang Franklin Chi, Fawzi Khoder‐Agha, Daniela Mennerich, Sakari Kellokumpu, Ilkka Miinalainen, Thomas Kietzmann, Elitsa Y. Dimova · 2020 · Redox Biology
  46. Vasoconstrictor Mechanisms in Chronic Hypoxia-Induced Pulmonary Hypertension: Role of Oxidant Signaling
    Simin Yan, Thomas C. Resta, Nikki L. Jernigan · 2020 · Antioxidants
  47. Inhibition of Notch signaling leads to increased intracellular ROS by up-regulating Nox4 expression in primary HUVECs
    Weixia Cai, Liang Liang, Li Wang, Juntao Han, Xiongxiang Zhu, Hua Han, Dahai Hu, Ping Zhang · 2014 · Cellular Immunology
  48. Protein Kinase C–Mediated Phosphorylation of p47phoxModulates Platelet-Derived Growth Factor–Induced H2O2Generation and Cell Proliferation in Human Umbilical Vein Endothelial Cells
    Felipe Simón, Andrés Stutzin · 2008 · Endothelium
  49. Correction: Targeting Vascular NADPH Oxidase 1 Blocks Tumor Angiogenesis through a PPARα Mediated Mechanism
    Sarah Garrido‐Urbani, Stéphane Jemelin, Christine Deffert, Stéphanie Carnésecchi, Olivier Basset, Cédric Szyndralewiez, Freddy Heitz, Patrick Page, Xavier Montet, Liliane Michalik et al. · 2011 · PLoS ONE
  50. Folic Acid Mitigates Angiotensin-II-Induced Blood Pressure and Renal Remodeling
    Sathnur Basappa Pushpakumar, Sourav Kundu, Naira S. Metreveli, Utpal Sen · 2013 · PLoS ONE
  51. Reactive oxygen species generation at the plasma membrane for antibody control
    F.L. Crane, Hans Löw · 2008 · Autoimmunity Reviews
  52. Pulmonary Endothelial Cell NOX
    Rachel L. Damico, Javier J. Zulueta, Paul M. Hassoun · 2012 · American Journal of Respiratory Cell and Molecular Biology
  53. Role of NADPH Oxidase-4 in Human Endothelial Progenitor Cells
    Nora Hakami, Amaresh Kumar Ranjan, Anandwardhan A. Hardikar, G. J. Dusting, Hitesh Peshavariya · 2017 · Frontiers in Physiology
  54. Regulation of NADPH Oxidases by G Protein-Coupled Receptors
    Andreas Petry, Agnes Görlach · 2018 · Antioxidants and Redox Signaling
  55. Proteomic Analysis of Endothelial Lipid Rafts Reveals a Novel Role of Statins in Antioxidation
    Mingxia Gu, Yi Fu, Xiaoli Sun, Yu-Zhu Ding, Chenghong Li, Wei Pang, Songqin Pan, Yi Zhu · 2012 · Journal of Proteome Research
  56. Molecular Characterization of the NADPH Oxidase Complex in the Ergot Fungus Claviceps purpurea : CpNox2 and CpPls1 Are Important for a Balanced Host-Pathogen Interaction
    Janine Schürmann, Dagmar Buttermann, Andrea Herrmann, Sabine Giesbert, Paul Tudzynski · 2013 · Molecular Plant-Microbe Interactions
  57. The NADPH oxidase NOX4 promotes the directed migration of endothelial cells by stabilizing vascular endothelial growth factor receptor 2 protein
    Kei Miyano, Shuichiro Okamoto, 明 山内, Chikage Kawai, Mizuho Kajikawa, Takuya Kiyohara, MINORU N. TAMURA, Masahiko Taura, Futoshi Kuribayashi · 2020 · Journal of Biological Chemistry
  58. High nuclear NADPH oxidase 4 expression levels are correlated with cancer development and poor prognosis in hepatocellular carcinoma
    Hyuk Soo Eun, Kwangsik Chun, In‐Sang Song, Cheong‐Hae Oh, In‐Ock Seong, Min‐Kyung Yeo, Kyung‐Hee Kim · 2019 · Pathology
  59. Evolutionary and structural analyses of the NADPH oxidase family in eukaryotes reveal an initial calcium dependency
    Marta Massari, Callum R. Nicoll, Sara Marchese, Andrea Mattevi, María Laura Mascotti · 2022 · Redox Biology
  60. Desbalanço redox: NADPH oxidase como um alvo terapêutico no manejo cardiovascular
    Luíza Antas Rabelo, Valéria Nunes de Souza, Lucas José Sá da Fonseca, Walkyria Oliveira Sampaio · 2010 · Arquivos Brasileiros de Cardiologia
  61. Volume-sensitive NADPH oxidase activity and taurine efflux in NIH3T3 mouse fibroblasts
    Martin Friis, Katrine Gribel Vorum, Ian Henry Lambert · 2008 · American Journal of Physiology-Cell Physiology
  62. SERPINA3K Plays Antioxidant Roles in Cultured Pterygial Epithelial Cells through Regulating ROS System
    Chengpeng Zhu, Fangyu Pan, Lianping Ge, Jing Zhou, Longlong Chen, Tong Zhou, Rongrong Zong, Xinye Xiao, Nuo Dong, Maomin Yang et al. · 2014 · PLoS ONE
  63. Imatinib and Nilotinib inhibit Bcr–Abl-induced ROS through targeted degradation of the NADPH oxidase subunit p22phox
    William D. Landry, John F. Woolley, Thomas G. Cotter · 2012 · Leukemia Research
  64. Prorenin receptor (PRR)-mediated NADPH oxidase (Nox) signaling regulates VEGF synthesis under hyperglycemic condition in ARPE-19 cells
    Rashidul Haque, Paul Michael Iuvone, Li He, Elizabeth H. Hur, Kimberly Su Chung Choi, Daniel Park, Annie Farrell, Ashley Ngo, Samantha Gokhale, Madiha Aseem et al. · 2017 · Journal of Receptors and Signal Transduction
  65. Antioxidant Mechanisms of the Oligopeptides (FWKVV and FMPLH) from Muscle Hydrolysate of Miiuy Croaker against Oxidative Damage of HUVECs
    Yuezhen Wang, Yumei Wang, Xin Yu Pan, Chang‐Feng Chi, Bin Wang · 2021 · Oxidative Medicine and Cellular Longevity
  66. NADPH-oxidases as potential pharmacological targets for thrombosis and depression comorbidity
    Patrizia Amadio, Leonardo Sandrini, Marta Zarà, Silvia Stella Barbieri, Alessandro Ieraci · 2024 · Redox Biology
  67. The transcriptional regulator CCCTC-binding factor limits oxidative stress in endothelial cells
    Anna R. Roy, Abdalla Ahmed, Peter V. DiStefano, Lijun Chi, Nadiya Khyzha, Niels Galjart, Michael D. Wilson, Jason E. Fish, Paul Delgado-Olguı́n · 2018 · Journal of Biological Chemistry
  68. Stabilization of p22phox by Hypoxia Promotes Pulmonary Hypertension
    Zuwen Zhang, Benjamin Trautz, Damir Kračun, Frederick Vogel, Michael Weitnauer, Katharina Hochkogler, Andreas Petry, Agnes Görlach · 2018 · Antioxidants and Redox Signaling
  69. Anti-Inflammatory CeO2 Nanoparticles Prevented Cytotoxicity Due to Exogenous Nitric Oxide Donors via Induction Rather Than Inhibition of Superoxide/Nitric Oxide in HUVE Cells
    Mohd Javed Akhtar, Maqusood Ahamed, Hisham A. Alhadlaq · 2021 · Molecules
  70. NADPH Oxidases, Angiogenesis, and Peripheral Artery Disease
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  71. TLR4 regulates pulmonary vascular homeostasis and remodeling via redox signaling
    Yabing Chen · 2015 · Frontiers in bioscience
  72. Advances in Fluorescence Techniques for the Detection of Hydroxyl Radicals near DNA and Within Organelles and Membranes
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  73. N-Acetylcysteine Modulates the Cytotoxic Effects of Paclitaxel
    Patricia Anne Lyle, Panagiotis Mitsopoulos, Zacharias E. Suntres · 2011 · Chemotherapy
  74. ROS-mediated Different Homeostasis of Murine Corneal Epithelial Progenitor Cell Line under Oxidative Stress
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  75. Nox4 promotes endothelial differentiation through chromatin remodeling
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  76. NOX1 Supports the Metabolic Remodeling of HepG2 Cells
    Katharina Bertram, Cristina‐Maria Vâlcu, Michael Weitnauer, Uwe Linne, Agnes Görlach · 2015 · PLoS ONE
  77. Endothelial Cell Reactive Oxygen Species and Ca2+ Signaling in Pulmonary Hypertension
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  78. Microvascular endothelial dysfunction in vascular senescence and disease
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  79. Laminar shear stress enhances endothelial cell survival through a NADPH oxidase 2-dependent mechanism
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    Nagendran Tharmalingam, Min Park, Min Ho Lee, Hyun Jun Woo, Hyun Woo Kim, Ji Yeong Yang, Ki-Jong Rhee, Jong Bae Kim · 2016 · PubMed Central
  82. Female mice lacking p47phoxhave altered adipose tissue gene expression and are protected against high fat-induced obesity
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  83. Endothelial Cell Dysfunction Due to Molecules Secreted by Macrophages in Sepsis
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  84. Correlation of Different NADPH Oxidase Homologues with Late Endothelial Progenitor Cell Senescence Induced by Angiotensin II: Effect of Telmisartan
    Hong Li, Qiang Liu, Ningfu Wang, Jian Xu · 2011 · Internal Medicine
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    Jie Hong, Murray B. Resnick, José Behar, Jack R. Wands, Ronald A. DeLellis, Weibiao Cao · 2011 · American Journal of Physiology-Cell Physiology
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  91. Lancemaside A from Codonopsis lanceolata prevents hypertension by inhibiting NADPH oxidase 2-mediated MAPK signalling and improving NO bioavailability in rats
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  92. A Cyclodiaryliodonium NOX Inhibitor for the Treatment of Pancreatic Cancer via Enzyme‐Activatable Targeted Delivery by Sulfated Glycosaminoglycan Derivatives
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  93. Cross Talk Between p22phox and ATF4 in the Endothelial Unfolded Protein Response
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  94. Inhibition of endothelial nitric oxyde synthase increases capillary formation via Rac1-dependent induction of hypoxia-inducible factor-1α and plasminogen activator inhibitor-1
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  95. Polysulfide nanoparticles inhibit fibroblast-to-myofibroblast transition via extracellular ROS scavenging and have potential anti-fibrotic properties
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