The Role of Oxidative Stress and Hypoxia in Pancreatic Beta-Cell Dysfunction in Diabetes Mellitus

Gerber, Philipp A., Rutter, Guy A.·2017·Antioxidants & Redox Signaling
DOI 10.1089/ars.2016.6755

Cites (218)

Items 201–219 of 219

  1. Role of NADPH Oxidase and Calcium in Cerulein‐Induced Apoptosis
    Ji Hoon Yu, Kyung Hwan Kim, Hyeyoung Kim · 2006 · Annals of the New York Academy of Sciences
  2. Adventures with Insulin in the Islets of Langerhans
    Donald F. Steiner · 2011 · Journal of Biological Chemistry
  3. Insulin increases H2O2-induced pancreatic beta cell death
    Sanford R. Sampson, Efrat Dahan Bucris, Miriam Horovitz‐Fried, A. Parnas, Sarit Kahana, Guila Abitbol, Moria Chetboun, Tovit Rosenzweig, Chaya Brodie, S. Frankel · 2010 · APOPTOSIS
  4. Attenuation of zinc-induced intracellular dysfunction and neurotoxicity by a synthetic superoxide dismutase/catalase mimetic, in cultured cortical neurons
    Kevin Pong, Yongqi Rong, Susan R. Doctrow, Michel Baudry · 2002 · Brain Research
  5. Metabolic evolution suggests an explanation for the weakness of antioxidant defences in beta-cells
    Armin Rashidi, Thomas B. L. Kirkwood, Daryl P. Shanley · 2009 · Mechanisms of Ageing and Development
  6. Acute nutrient regulation of the mitochondrial glutathione redox state in pancreatic β-cells
    H Takahashi, Laila R.B. Santos, Letícia Prates Roma, Jessica Duprez, Christophe Broca, Anne Wojtusciszyn, Jean‐Christophe Jonas · 2014 · Biochemical Journal
  7. Dorothy Hodgkin Lecture 2014 Understanding genes identified by genome‐wide association studies for Type 2 diabetes
    Guy A. Rutter · 2014 · Diabetic Medicine
  8. Preventing p38 MAPK-mediated MafA degradation ameliorates β-cell dysfunction under oxidative stress.
    I. El Khattabi, Arun J. Sharma · 2013 · Molecular Endocrinology
  9. The Zinc Ion Chelating Agent TPEN Attenuates Neuronal Death/apoptosis Caused by Hypoxia/ischemia Via Mediating the Pathophysiological Cascade Including Excitotoxicity, Oxidative Stress, and Inflammation
    Wei‐Ming Wang, Zhao Liu, Ai‐Jun Liu, Yuxiang Wang, Honggang Wang, Di An, Bin Heng, Lai‐Hua Xie, Junli Duan, Yan‐qiang Liu · 2015 · CNS Neuroscience & Therapeutics
  10. Beta-Cell Defence and Repair Mechanisms in Human Pancreatic Islets
    Decio Laks Eizirik · 1996 · Hormone and Metabolic Research
  11. Different susceptibility of rat pancreatic alpha and beta cells to hypoxia
    Konstantin O. Bloch, Julia Vennäng, Daniel Lazard, Pnina Vardi · 2012 · Histochemistry and Cell Biology
  12. Usurping the mitochondrial supremacy: Extramitochondrial sources of reactive oxygen intermediates and their role in beta cell metabolism and insulin secretion
    Joshua P. Gray, Emma A. Heart · 2010 · Toxicology Mechanisms and Methods
  13. Oral Administration of Bis(aspirinato)zinc(II) Complex Ameliorates Hyperglycemia and Metabolic Syndrome-Like Disorders in Spontaneously Diabetic KK-Ay Mice: Structure-Activity Relationship on Zinc-Salicylate Complexes
    Yutaka Yoshikawa, Yusuke Adachi, Hiroyuki Yasui, Masakazu Hattori, Hiromu Sakurai · 2011 · Chemical and Pharmaceutical Bulletin
  14. Metallothionein-III Provides Neuronal Protection through Activation of Nuclear Factor-κB via the TrkA/Phosphatidylinositol-3 kinase/Akt Signaling Pathway
    Hyung Gyun Kim, Yong Pil Hwang, Eun Hee Han, Chul Yung Choi, Chang‐Yeol Yeo, Jin Young Kim, Kwang Youl Lee, Hye Gwang Jeong · 2009 · Toxicological Sciences
  15. Targeted expression of Cre recombinase to myelinating cells of the central nervous system in transgenic mice
    Michiko Niwa‐Kawakita, Vincent Abramowski, Michel Kalamarides, Gilles D. Thomas, Marco Giovannini · 2000 · genesis
  16. Hypoxia acts through multiple signaling pathways to induce metallothionein transactivation by the metal-responsive transcription factor-1 (MTF-1)
    Annie Dubé, Jean-François Harrisson, Geneviève Saint-Gelais, Carl Séguin · 2011 · Biochemistry and Cell Biology
  17. Zinc pyrithione inhibits caspase-3 activity, promotes ErbB1-ErbB2 heterodimerization and suppresses ErbB2 downregulation in cardiomyocytes subjected to ischemia/reperfusion
    Vijaya Lakshmi Bodiga, Sandhya Thokala, Praveen Kumar Vemuri, Sreedhar Bodiga · 2015 · Journal of Inorganic Biochemistry
  18. Prevention of cell death by the zinc ion chelating agent TPEN in cultured PC12 cells exposed to Oxygen–Glucose Deprivation (OGD)
    Zhao Liu, Yue-yang Huang, Yuxiang Wang, Hong‐Gang Wang, Fēi Dèng, Bin Heng, Lai‐Hua Xie, Yan‐qiang Liu · 2015 · Journal of Trace Elements in Medicine and Biology
  19. Oxygenation of Cultured Pancreatic Islets
    Richard F. Olsson, Per‐Ola Carlsson · 2006 · Springer eBooks