The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Expression of Rat Liver Cytochrome P-450MC cDNA in Saccharomyces cerevisiae
Abstract
Rat liver cytochrome P-450MC cDNA was inserted between the ADH1 promoter and terminator regions of the yeast expression vector pAAH5. On introduction of the resulting recombinant plasmid pAMC1, Saccharomyces cerevisiae cells synthesized up to 8 X 10(5) molecules per cell of the cytochrome P-450MC protein, most of which was localized in yeast microsomes. Approximately half of the synthesized cytochrome contained heme in the enzyme molecule. These formed a functional electron-transport chain in the microsomes which exhibited aryl hydrocarbon hydroxylase activity toward benzo[a]pyrene.
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Citations
Cites
A rapid alkaline extraction procedure for screening recombinant plasmid DNA
Birnboim, H. C., & Doly, J. (1979) · Nucleic Acids Research · doi:10.1093/nar/7.6.1513 · Cited by 14,686
The Carbon Monoxide-binding Pigment of Liver Microsomes
Omura, T., & Sato, R. (1964) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)82244-3 · Cited by 11,781
Cited by
Guengerich, F. P. (1995) · Cytochrome P450 · doi:10.1007/978-1-4757-2391-5_14 · Cited by 728
17 beta-estradiol hydroxylation catalyzed by human cytochrome P450 1B1.
Hayes, C. L., Spink, D. C., Spink, B. C., Cao, J. Q., Walker, N. J., & Sutter, T. R. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.18.9776 · Cited by 632
Barnes, H. J., Arlotto, M. P., & Waterman, M. R. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.13.5597 · Cited by 558
Molecular genetics of the P-450 superfamily
Gonzalez, F. J. (1990) · Pharmacology & Therapeutics · doi:10.1016/0163-7258(90)90006-n · Cited by 493
Evidence That CYP2C19 is the Major (S)-Mephenytoin 4'-Hydroxylase in Humans
Goldstein, J. A., Faletto, M. B., Romkes-Sparks, M., Sullivan, T., Kitareewan, S., Raucy, J. L., Lasker, J. M., & Ghanayem, B. I. (1994) · Biochemistry · doi:10.1021/bi00173a017 · Cited by 360
Metadata
- Authors
- OEDA, K., SAKAKI, T., & OHKAWA, H.
- Venue
- DNA
- Publisher
- SAGE Publications
- Published
- 1985-06
- Volume
- 4
- Issue
- 3
- Pages
- 203-210
- ISSN
- 0198-0238 (ISSN-L)
- OpenAlex
- W1980829113
- Cited by
- 221
- References
- 2
- FWCI
- 8.62
- Type
- journal article
- Language
- en
- Open access
- closed
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- OEDA, K., SAKAKI, T., & OHKAWA, H. (1985). Expression of Rat Liver Cytochrome P-450MC cDNA in Saccharomyces cerevisiae. DNA. https://doi.org/10.1089/dna.1985.4.203
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
