Circumventing Antivector Immunity: Potential Use of Nonhuman Adenoviral Vectors

Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

Albert, M. L., Sauter, B., & Bhardwaj, N. (1998) · Nature · doi:10.1038/32183 · Cited by 2,350 · see citing works

Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer

Raper, S. E., Chirmule, N. B., Lee, F. S., Wivel, N. A., Bagg, A., Gao, G., Wilson, J. M., & Batshaw, M. L. (2003) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2003.08.016 · Cited by 1,502 · see citing works

Viruses and interferon: a fight for supremacy

Katze, M. G., He, Y., & Gale, M. (2002) · Nature Reviews Immunology · doi:10.1038/nri888 · Cited by 1,419 · see citing works

HCAR and MCAR: The human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses

Tomko, R. P., Xu, R., & Philipson, L. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.7.3352 · Cited by 1,200 · see citing works

Isolation of a Cytopathogenic Agent from Human Adenoids Undergoing Spontaneous Degeneration in Tissue Culture

Rowe, W. P., Huebner, R. J., Gilmore, L. K., Parrott, R. H., & Ward, T. G. (1953) · Experimental Biology and Medicine · doi:10.3181/00379727-84-20714 · Cited by 1,114 · see citing works

The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response

Muruve, D. A., Pétrilli, V., Zaiss, A. K., White, L. R., Clark, S. A., Ross, P. J., Parks, R. J., & Tschopp, J. (2008) · Nature · doi:10.1038/nature06664 · Cited by 936 · see citing works

Genetic content and evolution of adenoviruses

Davison, A. J., Benkő, M., & Harrach, B. (2003) · Journal of General Virology · doi:10.1099/vir.0.19497-0 · Cited by 700 · see citing works

Immune responses to transgene–encoded proteins limit the stability of gene expression after injection of replication–defective adenovirus vectors

Tripathy, S. K., Black, H. B., Goldwasser, E., & Leiden, J. M. (1996) · Nature Medicine · doi:10.1038/nm0596-545 · Cited by 627 · see citing works

A new adenoviral vector: Replacement of all viral coding sequences with 28 kb of DNA independently expressing both full-length dystrophin and beta-galactosidase.

Kochanek, S., Clemens, P. R., Mitani, K., Chen, H., Chan, S., & Caskey, C. T. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.12.5731 · Cited by 561 · see citing works

Comparative Seroprevalence and Immunogenicity of Six Rare Serotype Recombinant Adenovirus Vaccine Vectors from Subgroups B and D

Abbink, P., Lemckert, A. A. C., Ewald, B. A., Lynch, D. M., Denholtz, M., Smits, S., Holterman, L., Damen, I., Vogels, R., Thorner, A. R., et al. (2007) · Journal of Virology · doi:10.1128/jvi.02696-06 · Cited by 503 · see citing works

Hexon-chimaeric adenovirus serotype 5 vectors circumvent pre-existing anti-vector immunity

Roberts, D. M., Nanda, A., Havenga, M. J. E., Abbink, P., Lynch, D. M., Ewald, B. A., Liu, J., Thorner, A. R., Swanson, P. E., Gorgone, D. A., et al. (2006) · Nature · doi:10.1038/nature04721 · Cited by 490 · see citing works

Replication-Deficient Human Adenovirus Type 35 Vectors for Gene Transfer and Vaccination: Efficient Human Cell Infection and Bypass of Preexisting Adenovirus Immunity

Vogels, R., Zuijdgeest, D., van Rijnsoever, R., Hartkoorn, E., Damen, I., de Béthune, M., Kostense, S., Penders, G., Helmus, N., Koudstaal, W., et al. (2003) · Journal of Virology · doi:10.1128/jvi.77.15.8263-8271.2003 · Cited by 467 · see citing works

Accelerated vaccination for Ebola virus haemorrhagic fever in non-human primates

Sullivan, N. J., Geisbert, T. W., Geisbert, J. B., Xu, L., Yang, Z., Roederer, M., Koup, R. A., Jahrling, P. B., & Nabel, G. J. (2003) · Nature · doi:10.1038/nature01876 · Cited by 464 · see citing works

Adenovirus Binding to Blood Factors Results in Liver Cell Infection and Hepatotoxicity

Shayakhmetov, D. M., Gaggar, A., Ni, S., Li, Z.-Y., & Lieber, A. (2005) · Journal of Virology · doi:10.1128/jvi.79.12.7478-7491.2005 · Cited by 429 · see citing works

New Adenovirus Species Found in a Patient Presenting with Gastroenteritis

Jones, M. S., Balázs Harrach, B., Ganac, R. D., Gozum, M. M. A., Cruz, W. P. D., Riedel, B., Pan, C., Delwart, E., & Schnurr, D. P. (2007) · Journal of Virology · doi:10.1128/jvi.02650-06 · Cited by 384 · see citing works

Immunogenicity of Recombinant Adenovirus Serotype 35 Vaccine in the Presence of Pre-Existing Anti-Ad5 Immunity

Barouch, D. H., Pau, M. G., Custers, J. H. H. V., Koudstaal, W., Kostense, S., Havenga, M. J. E., Truitt, D. M., Sumida, S. M., Kishko, M., Arthur, J. C., et al. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.10.6290 · Cited by 383 · see citing works

Innate Immune Response to Adenoviral Vectors Is Mediated by both Toll-Like Receptor-Dependent and -Independent Pathways

Zhu, J., Huang, X., & Yang, Y. (2007) · Journal of Virology · doi:10.1128/jvi.02192-06 · Cited by 370 · see citing works

Neutralizing Antibodies to Adenovirus Serotype 5 Vaccine Vectors Are Directed Primarily against the Adenovirus Hexon Protein

Sumida, S. M., Truitt, D. M., Lemckert, A. A. C., Vogels, R., Custers, J. H. H. V., Addo, M. M., Lockman, S., PETER, T. F., Peyerl, F. W., Kishko, M., et al. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.174.11.7179 · Cited by 369 · see citing works

Efficient Gene Transfer into Human CD34 + Cells by a Retargeted Adenovirus Vector

Shayakhmetov, D. M., Papayannopoulou, T., Stamatoyannopoulos, G., & Lieber, A. (2000) · Journal of Virology · doi:10.1128/jvi.74.6.2567-2583.2000 · Cited by 367 · see citing works

Prevalence and Quantitation of Species C Adenovirus DNA in Human Mucosal Lymphocytes

Garnett‐Benson, C., Erdman, D. D., Xu, W., & Gooding, L. R. (2002) · Journal of Virology · doi:10.1128/jvi.76.21.10608-10616.2002 · Cited by 328 · see citing works

Analysis of 15 adenovirus hexon proteins reveals the location and structure of seven hypervariable regions containing serotype-specific residues

Crawford-Miksza, L. K., & Schnurr, D. P. (1996) · Journal of Virology · doi:10.1128/jvi.70.3.1836-1844.1996 · Cited by 326 · see citing works

Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes

Parker, A. L., Waddington, S. N., Nicol, C. G., Shayakhmetov, D. M., Buckley, S. M. K., Denby, L., Kemball‐Cook, G., Ni, S., Lieber, A., McVey, J. H., et al. (2006) · Blood · doi:10.1182/blood-2006-04-008532 · Cited by 297 · see citing works

Recent Advances in the Development of HIV-1 Vaccines Using Replication-Incompetent Adenovirus Vectors

Shiver, J. W., & Emini, E. A. (2004) · Annual Review of Medicine · doi:10.1146/annurev.med.55.091902.104344 · Cited by 280 · see citing works

Th1- and Th2-cell commitment during infectious disease: asymmetry in divergent pathways

Jankovic, D. L., Liu, Z., & Gause, W. C. (2001) · Trends in Immunology · doi:10.1016/s1471-4906(01)01975-5 · Cited by 272 · see citing works

Replication-Defective Vector Based on a Chimpanzee Adenovirus

Farina, S. F., Gao, G., Xiang, Z. Q., Rux, J. J., Burnett, R. M., Alvira, M. R., Marsh, J. A., Ertl, H. C. J., & Wilson, J. M. (2001) · Journal of Virology · doi:10.1128/jvi.75.23.11603-11613.2001 · Cited by 271 · see citing works

Targeting adenovirus to the serotype 3 receptor increases gene transfer efficiency to ovarian cancer cells.

Kanerva, A., Mikheeva, G., Krasnykh, V. N., Coolidge, C. J., Lam, J. T., Mahasreshti, P. J., Barker, S., Straughn, M. J., Barnes, M. N., Alvarez, R. D., et al. (2002) · PubMed · Cited by 255 · see citing works

Preferential transduction of neurons by canine adenovirus vectors and their efficient retrograde transport in vivo

Soudais, C., Laplace‐Builhé, C., Kissa, K., & Kremer, E. J. (2001) · The FASEB Journal · doi:10.1096/fj.01-0321fje · Cited by 250 · see citing works

Canine Adenovirus Vectors: an Alternative for Adenovirus-Mediated Gene Transfer

Kremer, E. J., Boutin, S., Chillón, M., & Danos, O. (2000) · Journal of Virology · doi:10.1128/jvi.74.1.505-512.2000 · Cited by 245 · see citing works

Adenovirus type 5 and 7 capsid chimera: fiber replacement alters receptor tropism without affecting primary immune neutralization epitopes

Gall, J. G. D., Kass-Eisler, A., Leinwand, L. A., & Falck-Pedersen, E. (1996) · Journal of Virology · doi:10.1128/jvi.70.4.2116-2123.1996 · Cited by 239 · see citing works

Evaluation of polyethylene glycol modification of first-generation and helper-dependent adenoviral vectors to reduce innate immune responses

Mok, H. S., Palmer, D. J., Ng, P., & Barry, M. A. (2004) · Molecular Therapy · doi:10.1016/j.ymthe.2004.09.015 · Cited by 232 · see citing works

Recombinant Adenovirus Serotype 26 (Ad26) and Ad35 Vaccine Vectors Bypass Immunity to Ad5 and Protect Nonhuman Primates against Ebolavirus Challenge

Geisbert, T. W., Bailey, M., Hensley, L. E., Asiedu, C. K., Geisbert, J. B., Stanley, D. A., Honko, A. N., Johnson, J. C., Mulangu, S., Pau, M. G., et al. (2011) · Journal of Virology · doi:10.1128/jvi.02407-10 · Cited by 224 · see citing works

Neutralization of adenoviruses: kinetics, stoichiometry, and mechanisms

Wohlfart, C. (1988) · Journal of Virology · doi:10.1128/jvi.62.7.2321-2328.1988 · Cited by 218 · see citing works

Virus Binding to a Plasma Membrane Receptor Triggers Interleukin-1α-Mediated Proinflammatory Macrophage Response In Vivo

Paolo, N. C. D., Miao, E. A., Iwakura, Y., Murali‐Krishna, K., Aderem, A. A., Flavell, R. A., Papayannopoulou, T., & Shayakhmetov, D. M. (2009) · Immunity · doi:10.1016/j.immuni.2009.04.015 · Cited by 206 · see citing works

“Sero-Switch” Adenovirus-Mediated In Vivo Gene Transfer: Circumvention of Anti-Adenovirus Humoral Immune Defenses Against Repeat Adenovirus Vector Administration by Changing the Adenovirus Serotype

Mastrangeli, A., Harvey, B., Yao, J., Wolff, G., Kovesdi, I., Crystal, R. G., & Falck-Pedersen, E. (1996) · Human Gene Therapy · doi:10.1089/hum.1996.7.1-79 · Cited by 204 · see citing works

Extended plasma circulation time and decreased toxicity of polymer-coated adenovirus

Green, N. K., Herbert, C. W., Hale, S. J. M., Hale, A., Mautner, V., Harkins, R. N., Hermiston, T. W., Ulbrich, K., Fisher, K., & Seymour, L. W. (2004) · Gene Therapy · doi:10.1038/sj.gt.3302295 · Cited by 204 · see citing works

Human erythrocytes bind and inactivate type 5 adenovirus by presenting Coxsackie virus-adenovirus receptor and complement receptor 1

Carlisle, R. C., Di, Y., Cerny, A., Sonnen, A. F. ‐., Sim, R. B., Green, N. K., Šubr, V., Ulbrich, K., Gilbert, R. J. C., Fisher, K., et al. (2009) · Blood · doi:10.1182/blood-2008-09-178459 · Cited by 203 · see citing works

Adenovirus receptors: implications for targeting of viral vectors

Arnberg, N. (2012) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2012.04.005 · Cited by 200 · see citing works

Clearance of Adenovirus by Kupffer Cells Is Mediated by Scavenger Receptors, Natural Antibodies, and Complement

Xu, Z., Tian, J., Smith, J. S., & Byrnes, A. P. (2008) · Journal of Virology · doi:10.1128/jvi.01320-08 · Cited by 199 · see citing works

Novel, Chimpanzee Serotype 68-Based Adenoviral Vaccine Carrier for Induction of Antibodies to a Transgene Product

Xiang, Z., Gao, G., Reyes‐Sandoval, A., Cohen, C. J., Li, Y., Bergelson, J. M., Wilson, J. M., & Ertl, H. C. J. (2002) · Journal of Virology · doi:10.1128/jvi.76.6.2667-2675.2002 · Cited by 194 · see citing works

Circumvention of Anti-Adenovirus Neutralizing Immunity by Administration of an Adenoviral Vector of an Alternate Serotype

Mack, C. A., Song, W., Carpenter, H., Wickham, T., Kovesdi, I., Harvey, B., Magovern, C. J., Isom, O. W., Rosengart, T. K., Falck-Pedersen, E., et al. (1997) · Human Gene Therapy · doi:10.1089/hum.1997.8.1-99 · Cited by 192 · see citing works

Signalling in viral entry

Greber, U. F. (2002) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-002-8453-3 · Cited by 186 · see citing works

Adenovirus Membrane Penetration Activates the NLRP3 Inflammasome

Barlan, A., Griffin, T., McGuire, K. A., & Wiethoff, C. M. (2010) · Journal of Virology · doi:10.1128/jvi.01265-10 · Cited by 181 · see citing works

Chimpanzee Adenovirus Antibodies in Humans, Sub-Saharan Africa

Xiang, Z., Li, Y., Cun, A., Yang, W. P., Ellenberg, S. S., Switzer, W. M., Kalish, M. L., & Ertl, H. C. J. (2006) · Emerging infectious diseases · doi:10.3201/eid1210.060078 · Cited by 178 · see citing works

Coagulation factor X shields adenovirus type 5 from attack by natural antibodies and complement

Xu, Z., Qiu, Q., Tian, J., Smith, J. S., Conenello, G. M., Morita, T., & Byrnes, A. P. (2013) · Nature Medicine · doi:10.1038/nm.3107 · Cited by 162 · see citing works

Type-Specific Epitope Locations Revealed by X-Ray Crystallographic Study of Adenovirus Type 5 Hexon

Rux, J. J., & Burnett, R. M. (2000) · Molecular Therapy · doi:10.1006/mthe.1999.0001 · Cited by 157 · see citing works

Novel Replication-Incompetent Vector Derived from Adenovirus Type 11 (Ad11) for Vaccination and Gene Therapy: Low Seroprevalence and Non-Cross-Reactivity with Ad5

Holterman, L., Vogels, R., van der Vlugt, R., Sieuwerts, M., Grimbergen, J. M., Kaspers, J., Geelen, E., van der Helm, E., Lemckert, A. A. C., Gillissen, G. F., et al. (2004) · Journal of Virology · doi:10.1128/jvi.78.23.13207-13215.2004 · Cited by 148 · see citing works

Adenovirus Serotype 5 Neutralizing Antibodies Target both Hexon and Fiber following Vaccination and Natural Infection

Bradley, R. R., Lynch, D. M., Iampietro, M. J., Borducchi, E. N., & Barouch, D. H. (2011) · Journal of Virology · doi:10.1128/jvi.06254-11 · Cited by 147 · see citing works

Molecular Evolution of Adenoviruses

Benkő, M., & Balázs Harrach, B. (2003) · Current topics in microbiology and immunology · doi:10.1007/978-3-662-05597-7_1 · Cited by 146 · see citing works

Conserved CTL epitopes on the adenovirus hexon protein expand subgroup cross-reactive and subgroup-specific CD8+ T cells

Leen, A. M., Sili, U., Vanin, E. F., Jewell, A. M., Xie, W., Vignali, D. A. A., Piedra, P. A., Brenner, M. K., & Rooney, C. M. (2004) · Blood · doi:10.1182/blood-2004-02-0646 · Cited by 143 · see citing works

Toll-like Receptor 9 Triggers an Innate Immune Response to Helper-dependent Adenoviral Vectors

Cerullo, V., Seiler, M. P., Mane, V. P., Brunetti‐Pierri, N., Clarke, C., Bertin, T., Rodgers, J. R., & Lee, B. (2007) · Molecular Therapy · doi:10.1038/sj.mt.6300031 · Cited by 143 · see citing works

Development of nonhuman adenoviruses as vaccine vectors

Bangari, D. S., & Mittal, S. K. (2005) · Vaccine · doi:10.1016/j.vaccine.2005.08.101 · Cited by 142 · see citing works

The adenovirus capsid: major progress in minor proteins

Vellinga, J., van der Heijdt, S., & Hoeben, R. C. (2005) · Journal of General Virology · doi:10.1099/vir.0.80877-0 · Cited by 140 · see citing works

A new adenoviral helper–dependent vector results in long-term therapeutic levels of human coagulation factor IX at low doses in vivo

Ehrhardt, A., & Kay, M. A. (2002) · Blood · doi:10.1182/blood.v99.11.3923 · Cited by 136 · see citing works

Modification of an Adenoviral Vector with Biologically Selected Peptides: A Novel Strategy for Gene Delivery to Cells of Choice

Romanczuk, H., Galer, C. E., Zabner, J., Barsomian, G., Wadsworth, S. C., & O’Riordan, C. R. (1999) · Human Gene Therapy · doi:10.1089/10430349950016654 · Cited by 134 · see citing works

Circumventing the immune response to adenovirus-mediated gene therapy.

Kass-Eisler, A., Leinwand, L. A., Gall, J. G. D., Bloom, B., & Falck-Pedersen, E. (1996) · PubMed · Cited by 134 · see citing works

Improved Adenovirus Vectors for Infection of Cardiovascular Tissues

Havenga, M. J. E., Lemckert, A. A. C., Grimbergen, J. M., Vogels, R., Huisman, L. G. M., Valerio, D., Bout, A., & Quax, P. H. A. (2001) · Journal of Virology · doi:10.1128/jvi.75.7.3335-3342.2001 · Cited by 133 · see citing works

Development of a Rapid Method for the PEGylation of Adenoviruses with Enhanced Transduction and Improved Stability under Harsh Storage Conditions

Croyle, M. A., Yu, Q.-C., & Wilson, J. M. (2000) · Human Gene Therapy · doi:10.1089/10430340050111368 · Cited by 132 · see citing works

The Cell Adhesion Molecule “CAR” and Sialic Acid on Human Erythrocytes Influence Adenovirus In Vivo Biodistribution

Seiradake, E., Henaff, D., Wodrich, H., Billet, O., Perreau, M., Hippert, C., Mennechet, F. J. D., Schoehn, G., Lortat‐Jacob, H., Dreja, H. S., et al. (2009) · PLoS Pathogens · doi:10.1371/journal.ppat.1000277 · Cited by 130 · see citing works

Development of adenovirus serotype 35 as a gene transfer vector

Reddy, P. S., Ganesh, S., Limbach, M. P., Brann, T. W., Pinkstaff, A., Kaloss, M., Kaleko, M., & Connelly, S. (2003) · Virology · doi:10.1016/s0042-6822(03)00161-2 · Cited by 130 · see citing works

Adenovirus receptors and their implications in gene delivery

Sharma, A., Li, X., Bangari, D. S., & Mittal, S. K. (2009) · Virus Research · doi:10.1016/j.virusres.2009.02.010 · Cited by 122 · see citing works

Canine Adenovirus Type 2 Attachment and Internalization: Coxsackievirus-Adenovirus Receptor, Alternative Receptors, and an RGD-Independent Pathway

Soudais, C., Boutin, S., Hong, S. S., Chillón, M., Danos, O., Bergelson, J. M., Boulanger, P. A., & Kremer, E. J. (2000) · Journal of Virology · doi:10.1128/jvi.74.22.10639-10649.2000 · Cited by 122 · see citing works

Tropism-Modification Strategies for Targeted Gene Delivery Using Adenoviral Vectors

Coughlan, L., Alba, R., Parker, A. L., Bradshaw, A. C., McNeish, I. A., Nicklin, S. A., & Baker, A. H. (2010) · Viruses · doi:10.3390/v2102290 · Cited by 120 · see citing works

Structure-Based Identification of a Major Neutralizing Site in an Adenovirus Hexon

Pichla-Gollon, S. L., Drinker, M. S., Zhou, X., Xue, F., Rux, J. J., Gao, G., Wilson, J. M., Ertl, H. C. J., Burnett, R. M., & Bergelson, J. M. (2006) · Journal of Virology · doi:10.1128/jvi.02023-06 · Cited by 115 · see citing works

Evidence of frequent recombination among human adenoviruses

Lukashev, A. N., Ivanova, O. E., Eremeeva, T. P., & Iggo, R. D. (2008) · Journal of General Virology · doi:10.1099/vir.0.83057-0 · Cited by 115 · see citing works

The Adenovirus Capsid Protein Hexon Contains a Highly Conserved Human CD4 + T-Cell Epitope

Olive, M., Eisenlohr, L. C., Flomenberg, N., Hsu, S. H., & Flomenberg, P. R. (2002) · Human Gene Therapy · doi:10.1089/104303402320138952 · Cited by 114 · see citing works

Effect of adenovirus serotype 5 fiber and penton modifications on in vivo tropism in rats

Nicol, C. G., Graham, D., Miller, W. H., White, S. J., Smith, T. A., Nicklin, S. A., Stevenson, S. C., & Baker, A. H. (2004) · Molecular Therapy · doi:10.1016/j.ymthe.2004.05.020 · Cited by 113 · see citing works

Circumvention of Immunity to the Adenovirus Major Coat Protein Hexon

Roy, S., Shirley, P. S., McClelland, A., & Kaleko, M. (1998) · Journal of Virology · doi:10.1128/jvi.72.8.6875-6879.1998 · Cited by 111 · see citing works

Purification and properties of chick embryo lethal orphan virus (an avian adenovirus)

Laver, W. G., Younghusband, H. B., & Wrigley, N. G. (1971) · Virology · doi:10.1016/0042-6822(71)90175-9 · Cited by 109 · see citing works

Comparative Analysis of the Magnitude, Quality, Phenotype, and Protective Capacity of Simian Immunodeficiency Virus Gag-Specific CD8+ T Cells following Human-, Simian-, and Chimpanzee-Derived Recombinant Adenoviral Vector Immunization

Quinn, K. M., Costa, A. D. S., Yamamoto, A., Berry, D., Lindsay, R. W. B., Darrah, P. A., Wang, L., Cheng, C., Kong, W., Gall, J. G. D., et al. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1202861 · Cited by 109 · see citing works

Phylogenetic Relationships among Adenovirus Serotypes

Bailey, A., & Mautner, V. (1994) · Virology · doi:10.1006/viro.1994.1664 · Cited by 108 · see citing works

Ovine Adenovirus Vectors Overcome Preexisting Humoral Immunity against Human Adenoviruses In Vivo

Hofmann, C., Löser, P., Cichon, G., Arnold, W., Both, G. W., & Strauss, M. (1999) · Journal of Virology · doi:10.1128/jvi.73.8.6930-6936.1999 · Cited by 108 · see citing works

Use of helper-dependent adenoviral vectors of alternative serotypes permits repeat vector administration

Parks, R. J., Evelegh, C. M., & Graham, F. L. (1999) · Gene Therapy · doi:10.1038/sj.gt.3300995 · Cited by 108 · see citing works

Computational Analysis of Two Species C Human Adenoviruses Provides Evidence of a Novel Virus

Walsh, M. P., Seto, J., Liu, E. B., Dehghan, S., Hudson, N. R., Lukashev, A. N., Ivanova, O. E., Chodosh, J., Dyer, D. W., Jones, M. S., et al. (2011) · Journal of Clinical Microbiology · doi:10.1128/jcm.00156-11 · Cited by 107 · see citing works

Construction and Characterization of Hexon-Chimeric Adenoviruses: Specification of Adenovirus Serotype

Gall, J. G. D., Crystal, R. G., & Falck-Pedersen, E. (1998) · Journal of Virology · doi:10.1128/jvi.72.12.10260-10264.1998 · Cited by 105 · see citing works

Evaluation of Biodistribution and Safety of Adenovirus Vectors Containing Group B Fibers After Intravenous Injection into Baboons

Ni, S., Bernt, K. M., Gaggar, A., Li, Z.-Y., Kiem, H., & Lieber, A. (2005) · Human Gene Therapy · doi:10.1089/hum.2005.16.664 · Cited by 104 · see citing works

Construction and Characterization of Adenovirus Serotype 5 Packaged by Serotype 3 Hexon

Wu, H., Dmitriev, I. P., Kashentseva, E. A., Seki, T., Wang, M., & Curiel, D. T. (2002) · Journal of Virology · doi:10.1128/jvi.76.24.12775-12782.2002 · Cited by 104 · see citing works

1364. Adenoviral Gene Therapy for Renal Cancer Requires Retargeting to Alternative Cellular Receptors

Haviv, Y. S., Blackwell, J. L., Kanerva, A., Nagi, P. A., Krasnykh, V. N., Dmitriev, I. P., Wang, M., Naito, S., Lei, X., Hemminki, A., et al. (2002) · Molecular Therapy · doi:10.1016/s1525-0016(16)44194-8 · Cited by 104 · see citing works

Adenovirus efficiently transduces plasmacytoid dendritic cells resulting in TLR9‐dependent maturation and IFN‐α production

Basner‐Tschakarjan, E., Gaffal, E., O’Keeffe, M. A., Tormo, D., Limmer, A., Wagner, H., Hochrein, H., & Tüting, T. (2006) · The Journal of Gene Medicine · doi:10.1002/jgm.964 · Cited by 102 · see citing works

Development and Assessment of Human Adenovirus Type 11 as a Gene Transfer Vector

Stone, D., Ni, S., Li, Z.-Y., Gaggar, A., Paolo, N. C. D., Feng, Q., Sandig, V., & Lieber, A. (2005) · Journal of Virology · doi:10.1128/jvi.79.8.5090-5104.2005 · Cited by 102 · see citing works

An Update on Canine Adenovirus Type 2 and Its Vectors

Bru, T., Salinas, S., & Kremer, E. J. (2010) · Viruses · doi:10.3390/v2092134 · Cited by 99 · see citing works

Intravenous Administration of Polyethylene Glycol-Coated (PEGylated) Proteins and PEGylated Adenovirus Elicits an Anti-PEG Immunoglobulin M Response

Shimizu, T., Ichihara, M., Yoshioka, Y., Ishida, T., Nakagawa, S., & Kiwada, H. (2012) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b12-00276 · Cited by 96 · see citing works

Adenovirus Serotype 5-Specific Neutralizing Antibodies Target Multiple Hexon Hypervariable Regions

Bradley, R. R., Maxfield, L. F., Lynch, D. M., Iampietro, M. J., Borducchi, E. N., & Barouch, D. H. (2011) · Journal of Virology · doi:10.1128/jvi.06165-11 · Cited by 95 · see citing works

Modification of Adenoviral Vectors With Polyethylene Glycol Modulates In Vivo Tissue Tropism and Gene Expression

Hofherr, S. E., Shashkova, E. V., Weaver, E. A., Khare, R., & Barry, M. A. (2008) · Molecular Therapy · doi:10.1038/mt.2008.86 · Cited by 95 · see citing works

Chromosomal Integration of Adenoviral Vector DNA In Vivo

Stephen, S. L., Montini, E., Sivanandam, V., Al-Dhalimy, M., Kestler, H., Finegold, M., Grompe, M., & Kochanek, S. (2010) · Journal of Virology · doi:10.1128/jvi.00751-10 · Cited by 92 · see citing works

Interaction of Adenovirus Type 5 Fiber with the Coxsackievirus and Adenovirus Receptor Activates Inflammatory Response in Human Respiratory Cells

Tamanini, A., Nicolis, E., Bonizzato, A., Bezzerri, V., Melotti, P., Assael, B. M., & Cabrini, G. (2006) · Journal of Virology · doi:10.1128/jvi.00721-06 · Cited by 91 · see citing works

Characterization of a Family of Chimpanzee Adenoviruses and Development of Molecular Clones for Gene Transfer Vectors

Roy, S., Gao, G., Lu, Y., Zhou, X., Lock, M. W., Calcedo, R., & Wilson, J. M. (2004) · Human Gene Therapy · doi:10.1089/10430340460745838 · Cited by 90 · see citing works

Mutational Analysis of the Avian Adenovirus CELO, Which Provides a Basis for Gene Delivery Vectors

Michou, A., Lehrmann, H., Saltik, M., & Cotten, M. L. (1999) · Journal of Virology · doi:10.1128/jvi.73.2.1399-1410.1999 · Cited by 90 · see citing works

Fowl adenovirus recombinant expressing VP2 of infectious bursal disease virus induces protective immunity against bursal disease

Sheppard, M., Werner, W., Tsatas, E., McCoy, R. J., Prowse, S. J., & Johnson, M. (1998) · Archives of Virology · doi:10.1007/s007050050342 · Cited by 89 · see citing works

Efficient gene transfer into human CD34+ cells by an adenovirus type 35 vector

Sakurai, F., Mizuguchi, H., & Hayakawa, T. (2003) · Gene Therapy · doi:10.1038/sj.gt.3301959 · Cited by 88 · see citing works

A Critical Role for Type I IFN–dependent NK Cell Activation in Innate Immune Elimination of Adenoviral Vectors In Vivo

Zhu, J., Huang, X., & Yang, Y. (2008) · Molecular Therapy · doi:10.1038/mt.2008.88 · Cited by 88 · see citing works

An improved helper-dependent adenoviral vector allows persistent gene expression after intramuscular delivery and overcomes preexisting immunity to adenovirus

Maione, D., Rocca, C. D., Giannetti, P., D’Arrigo, R., Liberatoscioli, L., Franlin, L. L., Sandig, V., Ciliberto, G., Monica, N. L., & Savino, R. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.101122498 · Cited by 88 · see citing works

Identification of Adenovirus Serotype 5 Hexon Regions That Interact with Scavenger Receptors

Khare, R., Reddy, V. S., Nemerow, G. R., & Barry, M. A. (2011) · Journal of Virology · doi:10.1128/jvi.05760-11 · Cited by 88 · see citing works

Role of MyD88 and TLR9 in the Innate Immune Response Elicited by Serotype 5 Adenoviral Vectors

Yamaguchi, T., Kawabata, K., Koizumi, N., Sakurai, F., Kaneda‐Nakashima, K., Sakurai, H., Sasaki, T., Okada, N., Yamanishi, K., & Mizuguchi, H. (2007) · Human Gene Therapy · doi:10.1089/hum.2007.016 · Cited by 87 · see citing works

Hexon Gene Switch Strategy for the Generation of Chimeric Recombinant Adenovirus

Youil, R., Toner, T. J., Su, Q., Chen, M., Tang, A., Bett, A. J., & Casimiro, D. R. (2002) · Human Gene Therapy · doi:10.1089/10430340252769824 · Cited by 87 · see citing works

A Novel Adenovirus Type 6 (Ad6)-Based Hepatitis C Virus Vector That Overcomes Preexisting Anti-Ad5 Immunity and Induces Potent and Broad Cellular Immune Responses in Rhesus Macaques

Capone, S., Meola, A., Ercole, B. B., Vitelli, A., Pezzanera, M., Ruggeri, L., Davies, M. E. M., Tafi, R., Santini, C., Luzzago, A., et al. (2006) · Journal of Virology · doi:10.1128/jvi.80.4.1688-1699.2006 · Cited by 87 · see citing works

Defining CAR as a cellular receptor for the avian adenovirus CELO using a genetic analysis of the two viral fibre proteins

Tan, P. K., Michou, A., Bergelson, J. M., & Cotten, M. L. (2001) · Journal of General Virology · doi:10.1099/0022-1317-82-6-1465 · Cited by 86 · see citing works

Virotherapy of Ovarian Cancer With Polymer-cloaked Adenovirus Retargeted to the Epidermal Growth Factor Receptor

Morrison, J., Briggs, S. S., Green, N. H., Fisher, K. D., Šubr, V., Ulbrich, K., Kehoe, S. T., & Seymour, L. W. (2007) · Molecular Therapy · doi:10.1038/sj.mt.6300363 · Cited by 86 · see citing works

Generation of a novel replication-incompetent adenoviral vector derived from human adenovirus type 49: manufacture on PER.C6 cells, tropism and immunogenicity

Lemckert, A. A. C., Grimbergen, J. M., Smits, S., Hartkoorn, E., Holterman, L., Berkhout, B., Barouch, D. H., Vogels, R., Quax, P. H. A., Goudsmit, J., et al. (2006) · Journal of General Virology · doi:10.1099/vir.0.82079-0 · Cited by 85 · see citing works

Scavenger Receptor A: A New Route for Adenovirus 5

Haisma, H. J., Boesjes, M., Beerens, A. M., van der Strate, B. W. A., Curiel, D. T., Plüddemann, A., Gordon, S., & Bellu, A. R. (2009) · Molecular Pharmaceutics · doi:10.1021/mp8000974 · Cited by 84 · see citing works

Human CD8+ cytotoxic T cell responses to adenovirus capsid proteins

Tang, J., Olive, M., Pulmanausahakul, R., Schnell, M. J., Flomenberg, N., Eisenlohr, L. C., & Flomenberg, P. R. (2006) · Virology · doi:10.1016/j.virol.2006.01.024 · Cited by 83 · see citing works

Mechanism of Ad5 Vaccine Immunity and Toxicity: Fiber Shaft Targeting of Dendritic Cells

Cheng, C., Gall, J. G. D., Kong, W., Sheets, R., Gomez, P. L., King, C. R., & Nabel, G. J. (2007) · PLoS Pathogens · doi:10.1371/journal.ppat.0030025 · Cited by 83 · see citing works

Seroprevalence of neutralizing antibodies to human adenoviruses type‐5 and type‐26 and chimpanzee adenovirus type‐68 in healthy Chinese adults

Zhang, S., Huang, W., Zhou, X., Zhao, Q., Wang, Q., & Jia, B. (2013) · Journal of Medical Virology · doi:10.1002/jmv.23546 · Cited by 82 · see citing works

Development of a bovine adenovirus type 3-based expression vector

Mittal, S. K., PREVEC, L., Graham, F. L., & Babiuk, L. A. (1995) · Journal of General Virology · doi:10.1099/0022-1317-76-1-93 · Cited by 82 · see citing works

Partial characterization of a new adenovirus lineage discovered in testudinoid turtles

Doszpoly, A., Wellehan, J. F. X., Childress, A. L., Tarján, Z. L., Kovács, E. R., Balázs Harrach, B., & Benkő, M. (2013) · Infection Genetics and Evolution · doi:10.1016/j.meegid.2013.03.049 · Cited by 80 · see citing works

A Recombinant E1-Deleted Canine Adenoviral Vector Capable of Transduction and Expression of a Transgene in Human-Derived Cells and In Vivo

Klonjkowski, B., Gilardi‐Hebenstreit, P., Hadchouel, J., Randrianarison-Huetz, V., Boutin, S., Yeh, P., Perricaudet, M., & Kremer, E. J. (1997) · Human Gene Therapy · doi:10.1089/hum.1997.8.17-2103 · Cited by 80 · see citing works

Human adenovirus type 35: nucleotide sequence and vector development

Gao, W., Robbins, P. D., & Gambotto, A. A. (2003) · Gene Therapy · doi:10.1038/sj.gt.3302097 · Cited by 80 · see citing works

Neutralizing antibodies to human and simian adenoviruses in humans and New-World monkeys

Ersching, J., Hernández, M. I. M., Cezarotto, F. S., Ferreira, J. D. S., Martins, A. B., Switzer, W. M., Xiang, Z., Ertl, H. C. J., Zanetti, C. R., & Pinto, A. R. (2010) · Virology · doi:10.1016/j.virol.2010.07.043 · Cited by 76 · see citing works

Effect of Neutralizing Sera on Factor X-Mediated Adenovirus Serotype 5 Gene Transfer

Parker, A. L., Waddington, S. N., Buckley, S. M. K., Custers, J. H. H. V., Havenga, M. J. E., van Rooijen, N., Goudsmit, J., McVey, J. H., Nicklin, S. A., & Baker, A. H. (2008) · Journal of Virology · doi:10.1128/jvi.01878-08 · Cited by 76 · see citing works

Sustained Improvement of Muscle Function One Year After Full-Length Dystrophin Gene Transfer into mdx Mice by a Gutted Helper-Dependent Adenoviral Vector

Dudley, R., Lu, Y., Gilbert, R., Matecki, S., Nalbantoglu, J. N., Petrof, B. J., & Karpati, G. (2004) · Human Gene Therapy · doi:10.1089/104303404772679959 · Cited by 72 · see citing works

Enhanced Adenovirus Infection of Melanoma Cells by Fiber-Modification: Incorporation of RGD Peptide or Ad5/3 Chimerism

Volk, A. L., Rivera, Á. A., Kanerva, A., Bauerschmitz, G. J., Dmitriev, I. P., Nettelbeck, D. M., & Curiel, D. T. (2003) · Cancer Biology & Therapy · doi:10.4161/cbt.2.5.440 · Cited by 72 · see citing works

Computational analysis of four human adenovirus type 4 genomes reveals molecular evolution through two interspecies recombination events

Dehghan, S., Seto, J., Liu, E. B., Walsh, M. P., Dyer, D. W., Chodosh, J., & Seto, D. (2013) · Virology · doi:10.1016/j.virol.2013.05.014 · Cited by 71 · see citing works

Three-Dimensional Structure of Canine Adenovirus Serotype 2 Capsid

Schoehn, G., Bakkouri, M. E., Fabry, C. M. S., Billet, O., Estrozi, L. F., Le, L. P., Curiel, D. T., Kajava, A. V., Ruigrok, R. W. H., & Kremer, E. J. (2008) · Journal of Virology · doi:10.1128/jvi.02393-07 · Cited by 71 · see citing works

Complex interactions with several arms of the complement system dictate innate and humoral immunity to adenoviral vectors

Appledorn, D., McBride, A. J., Seregin, S. S., Scott, J. M., Schuldt, N. J., Kiang, A., Godbehere, S., & Amalfitano, A. (2008) · Gene Therapy · doi:10.1038/gt.2008.114 · Cited by 70 · see citing works

Development of porcine adenovirus-3 as an expression vector.

Reddy, P. S., Idamakanti, N., Hyun, B., Tikoo, S. K., & Babiuk, L. A. (1999) · Journal of General Virology · doi:10.1099/0022-1317-80-3-563 · Cited by 69 · see citing works

Host Immune Responses to Chronic Adenovirus Infections in Human and Nonhuman Primates

Calcedo, R., Vandenberghe, L. H., Roy, S., Somanathan, S., Wang, L., & Wilson, J. M. (2008) · Journal of Virology · doi:10.1128/jvi.02160-08 · Cited by 68 · see citing works

Distribution of Mouse Adenovirus Type 1 in Intraperitoneally and Intranasally Infected Adult Outbred Mice

Kajon, A. E., Brown, C. C., & Spindler, K. R. (1998) · Journal of Virology · doi:10.1128/jvi.72.2.1219-1223.1998 · Cited by 67 · see citing works

Elimination of Innate Immune Responses and Liver Inflammation by PEGylation of Adenoviral Vectors and Methylprednisolone

Geest, B. D., Snoeys, J., Linthout, S. V., Lievens, J., & Collen, D. (2005) · Human Gene Therapy · doi:10.1089/hum.2005.16.1439 · Cited by 67 · see citing works

Chimpanzee adenovirus CV-68 adapted as a gene delivery vector interacts with the coxsackievirus and adenovirus receptor

Cohen, C. J., Xiang, Z., Gao, G., Ertl, H. C. J., Wilson, J. M., & Bergelson, J. M. (2002) · Journal of General Virology · doi:10.1099/0022-1317-83-1-151 · Cited by 67 · see citing works

Ad5:Ad48 Hexon Hypervariable Region Substitutions Lead to Toxicity and Increased Inflammatory Responses Following Intravenous Delivery

Coughlan, L., Bradshaw, A. C., Parker, A. L., Robinson, H. G., White, K. M., Custers, J. H. H. V., Goudsmit, J., van Roijen, N., Barouch, D. H., Nicklin, S. A., et al. (2012) · Molecular Therapy · doi:10.1038/mt.2012.162 · Cited by 67 · see citing works

Lysosomal localization and mechanism of membrane penetration influence nonenveloped virus activation of the NLRP3 inflammasome

Barlan, A., Danthi, P., & Wiethoff, C. M. (2011) · Virology · doi:10.1016/j.virol.2011.01.019 · Cited by 65 · see citing works

Characteristics of neutralizing antibodies to adenovirus capsid proteins in human and animal sera

Yu, B., Dong, J., Wang, C., Zhan, Y., Zhang, H., Wu, J., Kong, W., & Yu, X. (2013) · Virology · doi:10.1016/j.virol.2012.12.014 · Cited by 65 · see citing works

Incorporation of a laminin-derived peptide (SIKVAV) on polymer-modified adenovirus permits tumor-specific targeting via α6-integrins

Stevenson, M., Hale, A., Hale, S. J. M., Green, N. K., Black, G. C. M., Fisher, K., Ulbrich, K., Fabra, À., & Seymour, L. W. (2007) · Cancer Gene Therapy · doi:10.1038/sj.cgt.7701022 · Cited by 65 · see citing works

Gene therapy for prostate cancer delivered by ovine adenovirus and mediated by purine nucleoside phosphorylase and fludarabine in mouse models

Voeks, D. J., Martiniello‐Wilks, R., Madden, V., Smith, K., Bennetts, E., Both, G. W., & Russell, P. J. (2002) · Gene Therapy · doi:10.1038/sj.gt.3301698 · Cited by 63 · see citing works

Comparative transduction efficiencies of human and nonhuman adenoviral vectors in human, murine, bovine, and porcine cells in culture

Bangari, D. S., Shukla, S., & Mittal, S. K. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.12.099 · Cited by 63 · see citing works

Genomic and Bioinformatics Analysis of HAdV-4, a Human Adenovirus Causing Acute Respiratory Disease: Implications for Gene Therapy and Vaccine Vector Development

Purkayastha, A., Ditty, S. E., Su, J., McGraw, J., Hadfield, T. L., Tibbetts, C., & Seto, D. (2005) · Journal of Virology · doi:10.1128/jvi.79.4.2559-2572.2005 · Cited by 62 · see citing works

Human Dendritic Cell Maturation by Adenovirus Transduction Enhances Tumor Antigen-Specific T-Cell Responses

Schumacher, L., Ribas, A., Dissette, V. B., McBride, W. H., Mukherji, B., Economou, J. S., & Butterfield, L. H. (2004) · Journal of Immunotherapy · doi:10.1097/00002371-200405000-00003 · Cited by 60 · see citing works

Antiviral Antibodies Target Adenovirus to Phagolysosomes and Amplify the Innate Immune Response

Zaiss, A. K., Vilaysane, A., Cotter, M. J., Clark, S. A., Meijndert, H. C., Colarusso, P., Yates, R. M., Pétrilli, V., Tschopp, J., & Muruve, D. A. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0804269 · Cited by 58 · see citing works

Construction of Ovine Adenovirus Recombinants by Gene Insertion or Deletion of Related Terminal Region Sequences

Xu, Z. Z., Hyatt, A. D., Boyle, D. B., & Both, G. W. (1997) · Virology · doi:10.1006/viro.1997.8452 · Cited by 58 · see citing works

Porcine adenoviral vectors evade preexisting humoral immunity to adenoviruses and efficiently infect both human and murine cells in culture

Bangari, D. S., & Mittal, S. K. (2004) · Virus Research · doi:10.1016/j.virusres.2004.05.003 · Cited by 57 · see citing works

Replacing adenoviral vector HVR1 with a malaria B cell epitope improves immunogenicity and circumvents preexisting immunity to adenovirus in mice

Shiratsuchi, T., Rai, U., Krause, A., Worgall, S., & Tsuji, M. (2010) · Journal of Clinical Investigation · doi:10.1172/jci39812 · Cited by 55 · see citing works

Adenovirus type 5 with modified hexons induces robust transgene‐specific immune responses in mice with pre‐existing immunity against adenovirus type 5

Abe, S., Okuda, K., Ura, T., Kondo, A., Yoshida, A., Yoshizaki, S., Mizuguchi, H., Klinman, D. M., & Shimada, M. (2009) · The Journal of Gene Medicine · doi:10.1002/jgm.1332 · Cited by 53 · see citing works

Antibody response and virus tissue distribution in chickens inoculated with wild-type and recombinant fowl adenoviruses

Ojkić, D., & Nagy, É. (2003) · Vaccine · doi:10.1016/s0264-410x(03)00544-9 · Cited by 52 · see citing works

Bovine adenovirus serotype 3 utilizes sialic acid as a cellular receptor for virus entry

Li, X., Bangari, D. S., Sharma, A., & Mittal, S. K. (2009) · Virology · doi:10.1016/j.virol.2009.06.029 · Cited by 50 · see citing works

The Long Repeat Region Is Dispensable for Fowl Adenovirus Replication in Vitro

Ojkić, D., & Nagy, É. (2001) · Virology · doi:10.1006/viro.2000.0890 · Cited by 50 · see citing works

Bioprocess development for canine adenovirus type 2 vectors

Fernandes, P., Peixoto, C., Santiago, V. M., Kremer, E. J., Coroadinha, A. S., & Alves, P. M. (2012) · Gene Therapy · doi:10.1038/gt.2012.52 · Cited by 50 · see citing works

Porcine adenovirus-3 as a helper-dependent expression vector

Reddy, P. S., Idamakanti, N., Babiuk, L. A., Mehtali, M., & Tikoo, S. K. (1999) · Journal of General Virology · doi:10.1099/0022-1317-80-11-2909 · Cited by 49 · see citing works

Comparative analysis of vector biodistribution, persistence and gene expression following intravenous delivery of bovine, porcine and human adenoviral vectors in a mouse model

Sharma, A., Bangari, D. S., Tandon, M., Pandey, A., HogenEsch, H., & Mittal, S. K. (2009) · Virology · doi:10.1016/j.virol.2009.01.008 · Cited by 48 · see citing works

Mouse Adenovirus Type-1 Replication Is Restricted to Vascular Endothelium in the CNS of Susceptible Strains of Mice

Charles, P. C., Guida, J. D., Brosnan, C. F., & Horwitz, M. S. (1998) · Virology · doi:10.1006/viro.1998.9180 · Cited by 47 · see citing works

Construction of Avian Adenovirus CELO Recombinants in Cosmids

François, A., Eterradossi, N., Delmas, B., Payet, V., & Langlois, P. (2001) · Journal of Virology · doi:10.1128/jvi.75.11.5288-5301.2001 · Cited by 47 · see citing works

Construction and characterization of human adenovirus serotype 3 packaged by serotype 7 hexon

Tian, X., Su, X., Li, H., Li, X., Zhou, Z., Liu, W., & Zhou, R. (2011) · Virus Research · doi:10.1016/j.virusres.2011.06.017 · Cited by 44 · see citing works

Creation of a panel of vectors based on ape adenovirus isolates

Roy, S., Medina‐Jaszek, A., Wilson, M. J., Sandhu, A. K., Calcedo, R., Lin, J., & Wilson, J. M. (2010) · The Journal of Gene Medicine · doi:10.1002/jgm.1530 · Cited by 43 · see citing works

Bovine adenovirus type 3 internalization is independent of primary receptors of human adenovirus type 5 and porcine adenovirus type 3

Bangari, D. S., Sharma, A., & Mittal, S. K. (2005) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2005.04.058 · Cited by 43 · see citing works

Novel Human Gene Transfer Vectors: Evaluation of Wild-Type and Recombinant Animal Adenoviruses in Human-Derived Cells

Rasmussen, U. B., Benchaibi, M., Meyer, V., Schlesinger, Y., & Schughart, K. (1999) · Human Gene Therapy · doi:10.1089/10430349950016636 · Cited by 42 · see citing works

Enhanced gene transfer activity of peptide-targeted gene-delivery vectors

Parker, A. L., Fisher, K. D., Oupický, D., Read, M. L., Nicklin, S. A., Baker, A. H., & Seymour, L. W. (2005) · Journal of drug targeting · doi:10.1080/10611860400020449 · Cited by 42 · see citing works

Influence of Fiber Detargeting on Adenovirus-Mediated Innate and Adaptive Immune Activation

Schoggins, J. W., Nociari, M., Philpott, N. J., & Falck-Pedersen, E. (2005) · Journal of Virology · doi:10.1128/jvi.79.18.11627-11637.2005 · Cited by 40 · see citing works

Optimized PEGylated Adenovirus Vector Reduces the Anti-vector Humoral Immune Response against Adenovirus and Induces a Therapeutic Effect against Metastatic Lung Cancer

Eto, Y., Yoshioka, Y., Ishida, T., Yao, X., Morishige, T., Narimatsu, S., Mizuguchi, H., Mukai, Y., Okada, N., Kiwada, H., et al. (2010) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.33.1540 · Cited by 40 · see citing works

Cetuximab Retargeting of Adenovirus via the Epidermal Growth Factor Receptor for Treatment of Intraperitoneal Ovarian Cancer

Morrison, J., Briggs, S. S., Green, N. K., Thoma, C., Fisher, K. D., Kehoe, S. T., & Seymour, L. W. (2009) · Human Gene Therapy · doi:10.1089/hum.2008.167 · Cited by 40 · see citing works

Human adenovirus type 35 vector for gene therapy of brain cancer: improved transduction and bypass of pre-existing anti-vector immunity in cancer patients

Brouwer, E., Havenga, M. J. E., Ophorst, O. J. A. E., de Leeuw, B., Gijsbers, L., Gillissen, G. F., Hoeben, R. C., ter Horst, M., Nanda, D., Dirven, C. M. F., et al. (2006) · Cancer Gene Therapy · doi:10.1038/sj.cgt.7701010 · Cited by 40 · see citing works

Modification of Ad5 Hexon Hypervariable Regions Circumvents Pre-Existing Ad5 Neutralizing Antibodies and Induces Protective Immune Responses

Bruder, J. T., Semenova, E. A., Chen, P., Limbach, K. J., Patterson, N. B., Stefaniak, M. E., Konovalova, S., Thomas, C. A., Hamilton, M. M., King, C. R., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0033920 · Cited by 40 · see citing works

Novel Immunocompetent Murine Tumor Model for Evaluation of Conditionally Replication-Competent (Oncolytic) Murine Adenoviral Vectors

Robinson, M. J., Li, B., Ge, Y. C., Ko, D., Yendluri, S., Harding, T. A., VanRoey, M. J., Spindler, K. R., & Jooss, K. U. (2009) · Journal of Virology · doi:10.1128/jvi.02561-08 · Cited by 40 · see citing works

Biodistribution and inflammatory profiles of novel penton and hexon double-mutant serotype 5 adenoviruses

Bradshaw, A. C., Coughlan, L., Miller, A. M., Alba, R., van Rooijen, N., Nicklin, S. A., & Baker, A. H. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.05.025 · Cited by 39 · see citing works

Gene‐directed enzyme prodrug therapy for prostate cancer in a mouse model that imitates the development of human disease

Martiniello‐Wilks, R., Dane, A. P., Voeks, D. J., Jeyakumar, G., Mortensen, E., Shaw, J. M., Wang, X. Y., Both, G. W., & Russell, P. J. (2004) · The Journal of Gene Medicine · doi:10.1002/jgm.474 · Cited by 39 · see citing works

Targeting adenovirus to CD80 and CD86 receptors increases gene transfer efficiency to malignant glioma cells

Ulasov, I. V., Rivera, Á. A., Han, Y., Curiel, D. T., Zhu, Z. B., & Lesniak, M. S. (2007) · Journal of neurosurgery · doi:10.3171/jns-07/09/0617 · Cited by 39 · see citing works

Trafficking and Propagation of Canine Adenovirus Vectors Lacking a Known Integrin-Interacting Motif

Chillón, M., & Kremer, E. J. (2001) · Human Gene Therapy · doi:10.1089/104303401750476302 · Cited by 39 · see citing works

Use of chimeric adenoviral vectors to assess capsid neutralization determinants

Roy, S., Clawson, D. S., Calcedo, R., Lebherz, C., Sanmiguel, J. C., Wu, D., & Wilson, J. M. (2005) · Virology · doi:10.1016/j.virol.2004.12.029 · Cited by 38 · see citing works

The ups and downs of adenovirus vectors.

Ginsberg, H. S. (1996) · Europe PMC (PubMed Central) · Cited by 37 · see citing works

Pseudopackaging of Adenovirus Type 5 Genomes into Capsids Containing the Hexon Proteins of Adenovirus Serotypes B, D, or E

Ostapchuk, P., & Hearing, P. (2001) · Journal of Virology · doi:10.1128/jvi.75.1.45-51.2001 · Cited by 37 · see citing works

Inhibitory effects of human sera on adenovirus-mediated gene transfer into rat liver.

Kuriyama, S., Tominaga, K., Kikukawa, M., Nakatani, T., Tsujinoue, H., Yamazaki, M., Nagao, S., Toyokawa, Y., Mitoro, A., & Fukui, H. (1998) · PubMed · Cited by 37 · see citing works

Porcine adenovirus as a delivery system for swine vaccines and immunotherapeutics

Hammond, J. M., & Johnson, M. A. (2003) · The Veterinary Journal · doi:10.1016/j.tvjl.2003.09.007 · Cited by 36 · see citing works

Mouse Adenovirus Type 1 Infection in SCID Mice: an Experimental Model for Antiviral Therapy of Systemic Adenovirus Infections

Lenaerts, L., Verbeken, E. K., Clercq, E. D., & Naesens, L. M. J. (2005) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.49.11.4689-4699.2005 · Cited by 35 · see citing works

Ovine atadenovirus: a review of its biology, biosafety profile and application as a gene delivery vector

Both, G. W. (2004) · Immunology and Cell Biology · doi:10.1046/j.0818-9641.2004.01223.x · Cited by 33 · see citing works

Gene Expression by Atypical Recombinant Ovine Adenovirus Vectors during Abortive Infection of Human and Animal Cellsin Vitro

Khatri, A., Xu, Z. Z., & Both, G. W. (1997) · Virology · doi:10.1006/viro.1997.8861 · Cited by 33 · see citing works

Akt/Protein Kinase B Activation by Adenovirus Vectors Contributes to NFκB-Dependent CXCL10 Expression

Liu, Q., White, L. R., Clark, S. A., Heffner, D. J., Winston, B. W., Tibbles, L. A., & Muruve, D. A. (2005) · Journal of Virology · doi:10.1128/jvi.79.23.14507-14515.2005 · Cited by 33 · see citing works

Regulation of antigen presentation machinery in human dendritic cells by recombinant adenovirus

Vujanovic, L. N., Whiteside, T. L., Potter, D. M., Chu, J., Ferrone, S., & Butterfield, L. H. (2008) · Cancer Immunology Immunotherapy · doi:10.1007/s00262-008-0533-2 · Cited by 32 · see citing works

Protection of adenovirus from neutralizing antibody by cationic PEG derivative ionically linked to adenovirus

Sun, X., Han, H., Zhao, Gong, T., Zhi-RongZhang, & Sun, X. (2012) · International Journal of Nanomedicine · doi:10.2147/ijn.s27526 · Cited by 32 · see citing works

Ovine adenovirus vectors mediate efficient gene transfer to skeletal muscle

Löser, P., Hillgenberg, M., Arnold, W., Both, G. W., & Hofmann, C. (2000) · Gene Therapy · doi:10.1038/sj.gt.3301260 · Cited by 32 · see citing works

Potential viral vectors for the stimulation of mucosal antibody responses against enteric viral antigens in pigs

Tuboly, T., Nagy, É., & Derbyshire, J. B. (1993) · Research in Veterinary Science · doi:10.1016/0034-5288(93)90133-z · Cited by 31 · see citing works

Altered Tropism of an Ovine Adenovirus Carrying the Fiber Protein Cell Binding Domain of Human Adenovirus Type 5

Xu, Z. Z., & Both, G. W. (1998) · Virology · doi:10.1006/viro.1998.9261 · Cited by 31 · see citing works

Adenoviruses 16 and CV23 Efficiently Transduce Human Low-passage Brain Tumor and Cancer Stem Cells

Skog, J., Edlund, K., Bergenheim, A. T., & Wadell, G. (2007) · Molecular Therapy · doi:10.1038/sj.mt.6300315 · Cited by 30 · see citing works

The non-essential left end region of the fowl adenovirus 9 genome is suitable for foreign gene insertion/replacement

Corredor, J. C., & Nagy, É. (2010) · Virus Research · doi:10.1016/j.virusres.2010.01.014 · Cited by 28 · see citing works

Construction and Transfection of Ovine Adenovirus Genomic Clones to Rescue Modified Viruses

Vrati, S., MacAvoy, E. S., Xu, Z. Z., SMOLE, C., Boyle, D. B., & Both, G. W. (1996) · Virology · doi:10.1006/viro.1996.0300 · Cited by 28 · see citing works

The Number of Toll-Like Receptor 9-Agonist Motifs in the Adenovirus Genome Correlates with Induction of Dendritic Cell Maturation by Adenovirus Immune Complexes

Perreau, M., Welles, H. C., Pellaton, C., Gjoksi, B., Potin, L., Martin, R., Harari, A., Bett, A. J., Casimiro, D. R., Gall, J. G. D., et al. (2012) · Journal of Virology · doi:10.1128/jvi.00123-12 · Cited by 28 · see citing works

Altered tropism of recombinant bovine adenovirus type-3 expressing chimeric fiber

Wu, Q. (2003) · Virus Research · doi:10.1016/j.virusres.2003.09.009 · Cited by 27 · see citing works

The Conundrum Between Immunological Memory to Adenovirus and Their Use as Vectors in Clinical Gene Therapy

Perreau, M., & Kremer, E. J. (2006) · Molecular Biotechnology · doi:10.1385/mb:34:2:247 · Cited by 27 · see citing works

Restoration of p53 tumor-suppressor activity in human tumor cells in vitro and in their xenografts in vivo by recombinant avian adenovirus CELO-p53

Logunov, D. Y., Ilyinskaya, G. W., Черенова, Л. В., Verhovskaya, L., Шмаров, М. М., Chumakov, P. M., Kopnin, B. P., & Naroditsky, B. S. (2003) · Gene Therapy · doi:10.1038/sj.gt.3302146 · Cited by 27 · see citing works

Decreased immune reactivity towards a knobless, affibody-targeted adenovirus type 5 vector

Myhre, S., Henning, P., Granio, O., Tylö, A. S., Nygren, P., Olofsson, S. ‐., Boulanger, P. A., Lindholm, L., & Hong, S.-S. (2006) · Gene Therapy · doi:10.1038/sj.gt.3302875 · Cited by 27 · see citing works

Construction, Rescue, and Characterization of Vectors Derived from Ovine Atadenovirus

Löser, P., Hofmann, C., Both, G. W., Uckert, W., & Hillgenberg, M. (2003) · Journal of Virology · doi:10.1128/jvi.77.22.11941-11951.2003 · Cited by 27 · see citing works

Genomic and bioinformatics analysis of HAdV-7, a human adenovirus of species B1 that causes acute respiratory disease: implications for vector development in human gene therapy

Purkayastha, A., Su, J., Carlisle, S., Tibbetts, C., & Seto, D. (2004) · Virology · doi:10.1016/j.virol.2004.10.041 · Cited by 26 · see citing works

Efficient Transduction of Human Monocyte-Derived Dendritic Cells by Chimpanzee-Derived Adenoviral Vector

Varnavski, A. N., Schlienger, K., Bergelson, J. M., Gao, G., & Wilson, J. M. (2003) · Human Gene Therapy · doi:10.1089/104303403764539323 · Cited by 26 · see citing works

Porcine adenovirus serotype 3 internalization is independent of CAR and αvβ3 or αvβ5 integrin

Bangari, D. S., & Mittal, S. K. (2004) · Virology · doi:10.1016/j.virol.2004.11.010 · Cited by 26 · see citing works

Helper-dependent canine adenovirus vector-mediated transgene expression in a neurodegenerative lysosomal storage disorder

Lau, A. A., Rozaklis, T., Ibanes, S., Luck, A. J., Beard, H., Hassiotis, S., Mazouni, K., Hopwood, J. J., Kremer, E. J., & Hemsley, K. M. (2011) · Gene · doi:10.1016/j.gene.2011.09.004 · Cited by 26 · see citing works

Chromatography Purification of Canine Adenoviral Vectors

Segura, M. M., Puig, M., Monfar, M., & Chillón, M. (2012) · Human Gene Therapy Methods · doi:10.1089/hgtb.2012.058 · Cited by 25 · see citing works

The transduction of Coxsackie and Adenovirus Receptor-negative cells and protection against neutralizing antibodies by HPMA-co-oligolysine copolymer-coated adenovirus

Wang, C.-H. K., Chan, L. W., Johnson, R. N., Chu, D. S. H., Shi, J., Schellinger, J. G., Lieber, A., & Pun, S. H. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.08.069 · Cited by 24 · see citing works

Combined Antiapoptotic and Antioxidant Approach to Acute Neuroprotection for Stroke in Hypertensive Rats

Ord, E., Shirley, R. B., McClure, J., McCabe, C., Kremer, E. J., Macrae, I. M., & Work, L. M. (2013) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2013.70 · Cited by 24 · see citing works

Canine Adenovirus Type 2 Vector Generation via I-Sce1-Mediated Intracellular Genome Release

Ibanes, S., & Kremer, E. J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0071032 · Cited by 24 · see citing works

Biology of Ovine Adenovirus Infection of Nonpermissive Cells

Kümin, D., Hofmann, C., Rudolph, M., Both, G. W., & Löser, P. (2002) · Journal of Virology · doi:10.1128/jvi.76.21.10882-10893.2002 · Cited by 24 · see citing works

Avian adenovirus vector CELO-TK displays anticancer activity in human cancer cells and suppresses established murine melanoma tumors

Shashkova, E. V., Черенова, Л. В., Kazansky, D. B., & Doronin, K. (2005) · Cancer Gene Therapy · doi:10.1038/sj.cgt.7700822 · Cited by 23 · see citing works

Influence of chimeric human-bovine fibers on adenoviral uptake by liver cells and the antiviral immune response

Rogée, S., Grellier, E., Bernard, C., Jouy, N., Loyens, A., Beauvillain, J., Fender, P., Corjon, S., Hong, S. S., Boulanger, P. A., et al. (2010) · Gene Therapy · doi:10.1038/gt.2010.37 · Cited by 23 · see citing works

Analysis of early region 3 mutants of mouse adenovirus type 1

Beard, C. W., & Spindler, K. R. (1996) · Journal of Virology · doi:10.1128/jvi.70.9.5867-5874.1996 · Cited by 22 · see citing works

Usage of Integrin and Heparan Sulfate as Receptors for Mouse Adenovirus Type 1

Raman, S., Hsu, T.-H., Ashley, S. L., & Spindler, K. R. (2009) · Journal of Virology · doi:10.1128/jvi.02368-08 · Cited by 22 · see citing works

Sequential administration of bovine and human adenovirus vectors to overcome vector immunity in an immunocompetent mouse model of breast cancer

Tandon, M., Sharma, A., Vemula, S. V., Bangari, D. S., & Mittal, S. K. (2011) · Virus Research · doi:10.1016/j.virusres.2011.09.031 · Cited by 21 · see citing works

Differentiated Neuroprogenitor Cells Incubated with Human or Canine Adenovirus, or Lentiviral Vectors Have Distinct Transcriptome Profiles

Piersanti, S., Astrologo, L., Licursi, V., Costa, R., Roncaglia, E., Gennetier, A., Ibanes, S., Chillón, M., Negri, R., Tagliafico, E., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0069808 · Cited by 21 · see citing works

A region at the left end of the fowl adenovirus 9 genome that is non-essential in vitro has consequences in vivo

Corredor, J. C., & Nagy, É. (2009) · Journal of General Virology · doi:10.1099/vir.0.013839-0 · Cited by 21 · see citing works

Mouse adenovirus (MAV-1) expression in primary human endothelial cells and generation of a full-length infectious plasmid

Nguyen, T. T., Nery, J. P., Joseph, S., Rocha, C. E., Carney, G. E., Spindler, K. R., & Villarreal, L. P. (1999) · Gene Therapy · doi:10.1038/sj.gt.3300949 · Cited by 21 · see citing works

Interaction between Mouse Adenovirus Type 1 and Cell Surface Heparan Sulfate Proteoglycans

Lenaerts, L., van Dam, W., Persoons, L., & Naesens, L. M. J. (2012) · PLoS ONE · doi:10.1371/journal.pone.0031454 · Cited by 20 · see citing works

Development of an Ad7 cosmid system and generation of an Ad7ΔE1ΔE3HIVMN env/rev recombinant virus

Nan, X., Peng, B., Hahn, T.-W., Richardson, E., Lizonová, A., Kovesdi, I., & Robert-Guroff, M. (2003) · Gene Therapy · doi:10.1038/sj.gt.3301903 · Cited by 19 · see citing works

Characterization of human adenovirus 35 and derivation of complex vectors

McVey, D., Zuber, M., Ettyreddy, D., Reiter, C. D., Brough, D. E., Nabel, G. J., King, C. R., & Gall, J. G. D. (2010) · Virology Journal · doi:10.1186/1743-422x-7-276 · Cited by 19 · see citing works

In Vitro and In Vivo Characterization of a Mouse Adenovirus Type 1 Early Region 3 Null Mutant

Cauthen, A. N., Brown, C. C., & Spindler, K. R. (1999) · Journal of Virology · doi:10.1128/jvi.73.10.8640-8646.1999 · Cited by 18 · see citing works

Antibody fragments, expressed by a fowl adenovirus vector, are able to neutralize infectious bursal disease virus

Greenall, S. A., Tyack, S. G., Johnson, M. A., & Sapats, S. I. (2010) · Avian Pathology · doi:10.1080/03079457.2010.507239 · Cited by 18 · see citing works

Human papillomavirus vaccine against cervical cancer: Opportunity and challenge

Wang, R., Pan, W. D., Lei, J., Huang, W., Li, Y., Wu, D., Gao, C., Ma, D., & Liao, S. (2019) · Cancer Letters · doi:10.1016/j.canlet.2019.11.039 · Cited by 510 · see citing works

Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, and <i>Toxoplasma gondii</i> challenges with a single dose

Chahal, J. S., Khan, O. F., Cooper, C. L., McPartlan, J. S., Tsosie, J. K., Tilley, L. D., Sidik, S. M., Lourido, S., Langer, R., Bavari, S., et al. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1600299113 · Cited by 414 · see citing works

Unmodified mRNA in LNPs constitutes a competitive technology for prophylactic vaccines

Lutz, J., Lazzaro, S., Habbeddine, M., Schmidt, K. E., Baumhof, P., Mui, B. L., Tam, Y. K., Madden, T. D., Hope, M. J., Heidenreich, R., et al. (2017) · npj Vaccines · doi:10.1038/s41541-017-0032-6 · Cited by 257 · see citing works

Viral Vectors for the in Vivo Delivery of CRISPR Components: Advances and Challenges

Mengstie, M. A. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.895713 · Cited by 140 · see citing works

Viral and Non-Viral Systems to Deliver Gene Therapeutics to Clinical Targets

Taghdiri, M., & Mussolino, C. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25137333 · Cited by 126 · see citing works

Development of Novel Adenoviral Vectors to Overcome Challenges Observed With HAdV-5–based Constructs

Alonso-Padilla, J., Papp, T., Kaján, G. L., Benkő, M., Havenga, M. J. E., Lemckert, A. A. C., Balázs Harrach, B., & Baker, A. H. (2015) · Molecular Therapy · doi:10.1038/mt.2015.194 · Cited by 106 · see citing works

Oncolytic Adenovirus: Strategies and Insights for Vector Design and Immuno-Oncolytic Applications

Uusi-Kerttula, H. K., Hulin-Curtis, S. L., Davies, J. A., & Parker, A. L. (2015) · Viruses · doi:10.3390/v7112923 · Cited by 86 · see citing works

Oncolytic adenovirus: A tool for cancer therapy in combination with other therapeutic approaches

Goradel, N. H., Mohajel, N., Malekshahi, Z. V., Jahangiri, S., Najafi, M., Farhood, B., Mortezaee, K., Negahdari, B., & Arashkia, A. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.27850 · Cited by 79 · see citing works

Interaction of adenovirus with antibodies, complement, and coagulation factors

Allen, R. J., & Byrnes, A. P. (2019) · FEBS Letters · doi:10.1002/1873-3468.13649 · Cited by 56 · see citing works

Vector engineering, strategies and targets in cancer gene therapy

Singh, V., Khan, N., & Jayandharan, G. R. (2021) · Cancer Gene Therapy · doi:10.1038/s41417-021-00331-7 · Cited by 51 · see citing works

Adenovirus vector‐based prime‐boost vaccination via heterologous routes induces cervicovaginal CD8+ T cell responses against HPV16 oncoproteins

Çuburu, N., Khan, S., Thompson, C. D., Kim, R., Vellinga, J., Zahn, R. C., Lowy, D. R., Scheper, G. C., & Schiller, J. T. (2017) · International Journal of Cancer · doi:10.1002/ijc.31166 · Cited by 49 · see citing works

Safety and Immunogenicity of a Novel Recombinant Simian Adenovirus ChAdOx2 as a Vectored Vaccine

Folegatti, P. M., Bellamy, D. G., Roberts, R., Powlson, J., Edwards, N. J., Mair, C., Bowyer, G., Poulton, I. D., Mitton, C. H., Green, N., et al. (2019) · Vaccines · doi:10.3390/vaccines7020040 · Cited by 31 · see citing works

Getting genetic access to natural adenovirus genomes to explore vector diversity

Zhang, W., & Ehrhardt, A. (2017) · Virus Genes · doi:10.1007/s11262-017-1487-2 · Cited by 30 · see citing works

Overcoming the Delivery Challenges in CRISPR/Cas9 Gene Editing for Effective Cancer Treatment: A Review of Delivery Systems

Tang, S., Chen, X.-Y., Tong, X.-M., & Zhu, L.-F. (2025) · International Journal of Medical Sciences · doi:10.7150/ijms.112724 · Cited by 23 · see citing works

The influence of delivery vectors on HIV vaccine efficacy

Ondondo, B. (2014) · Frontiers in Microbiology · doi:10.3389/fmicb.2014.00439 · Cited by 29 · see citing works

Hitting the nail on the head: combining oncolytic adenovirus-mediated virotherapy and immunomodulation for the treatment of glioma

Panek, W. K., KANE, J. R., Young, J. S., Rashidi, A., Kim, J. W., Kanojia, D., & Lesniak, M. S. (2017) · Oncotarget · doi:10.18632/oncotarget.20810 · Cited by 28 · see citing works

Orf Virus-Based Vaccine Vector D1701-V Induces Strong CD8+ T Cell Response against the Transgene but Not against ORFV-Derived Epitopes

Reguzova, A., Ghosh, M., Müller, M., Rziha, H.-J., & Amann, R. (2020) · Vaccines · doi:10.3390/vaccines8020295 · Cited by 28 · see citing works

Recent Advancements in Cardiovascular Gene Therapy and Vascular Biology

Laakkonen, J. P., & Ylä‐Herttuala, S. (2015) · Human Gene Therapy · doi:10.1089/hum.2015.095 · Cited by 26 · see citing works

A Dendritic Cell-Targeted Adenoviral Vector Facilitates Adaptive Immune Response Against Human Glioma Antigen (CMV-IE) and Prolongs Survival in a Human Glioma Tumor Model

Kim, J. W., KANE, J. R., Panek, W. K., Young, J. S., Rashidi, A., Yu, D., Kanojia, D., Hasan, T., Miska, J. M., Gómez-Lim, M. Á., et al. (2018) · Neurotherapeutics · doi:10.1007/s13311-018-0650-3 · Cited by 26 · see citing works

Exploring the Potential and Challenges of CRISPR Delivery and Therapeutics for Genetic Disease Treatment

Yang, X., Bui, T. A., Mei, H., Aksoy, Y. A., Deng, F., Hutvágner, G., & Deng, W. (2024) · Advanced Functional Materials · doi:10.1002/adfm.202402630 · Cited by 25 · see citing works

Structure of a Reptilian Adenovirus Reveals a Phage Tailspike Fold Stabilizing a Vertebrate Virus Capsid

Menéndez-Conejero, R., Nguyen, T. H., Singh, A. K., Condezo, G. N., Marschang, R. E., van Raaij, M. J., & Martı́n, C. S. (2017) · Structure · doi:10.1016/j.str.2017.08.007 · Cited by 22 · see citing works

Meeting vaccine formulation challenges in an emergency setting: Towards the development of accessible vaccines

Peletta, A., Lemoine, C., Courant, T., Collin, N., & Borchard, G. (2023) · Pharmacological Research · doi:10.1016/j.phrs.2023.106699 · Cited by 21 · see citing works

Near-atomic structure of an atadenovirus reveals a conserved capsid-binding motif and intergenera variations in cementing proteins

Marabini, R., Condezo, G. N., Krupovìč, M., Menéndez-Conejero, R., Gómez-Blanco, J., & Martı́n, C. S. (2021) · Science Advances · doi:10.1126/sciadv.abe6008 · Cited by 21 · see citing works

Genome analysis of four Old World monkey adenoviruses supports the proposed species classification of primate adenoviruses and reveals signs of possible homologous recombination

Podgorski, I. I., Pantó, L., Papp, T., Balázs Harrach, B., & Benkő, M. (2016) · Journal of General Virology · doi:10.1099/jgv.0.000465 · Cited by 21 · see citing works

Longevity of adenovirus vector immunity in mice and its implications for vaccine efficacy

Sayedahmed, E. E., Kumari, R., Shukla, S., Hassan, A. O., Mohammed, S. I., York, I. A., Gangappa, S., Sambhara, S. R., & Mittal, S. K. (2018) · Vaccine · doi:10.1016/j.vaccine.2018.09.031 · Cited by 17 · see citing works

Novel hybrid silicon-lipid nanoparticles deliver a siRNA to cure autosomal dominant osteopetrosis in mice. Implications for gene therapy in humans

Maurizi, A., Patrizii, P., Teti, A. M., Sutera, F. M., Rachwalska, P., Burns, C., Nandi, U., Welsh, M. J., Torabi‐Pour, N., Dehsorkhi, A., et al. (2023) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2023.08.020 · Cited by 17 · see citing works

Cardiac Nerve Growth Factor Overexpression Induces Bone Marrow–derived Progenitor Cells Mobilization and Homing to the Infarcted Heart

Meloni, M., Cesselli, D., Caporali, A., Mangialardi, G., Avolio, E., Reni, C., Fortunato, O., Martini, S., Madeddu, P. R., Valgimigli, M., et al. (2015) · Molecular Therapy · doi:10.1038/mt.2015.167 · Cited by 16 · see citing works

Restriction-Assembly: A Solution to Construct Novel Adenovirus Vector

Guo, X., Sun, Y., Chen, J., Zou, X., Hou, W., Tan, W., Hung, T., & Lu, Z. (2022) · Viruses · doi:10.3390/v14030546 · Cited by 15 · see citing works

Immunogenicity of High-Dose MVA-Based MERS Vaccine Candidate in Mice and Camels

Alharbi, N. K., Aljamaan, F., Aljami, H. A., Alenazi, M. W., Albalawi, H., Almasoud, A. S., Alharthi, F. J., Azhar, E. I., Barhoumi, T., Bosaeed, M., et al. (2022) · Vaccines · doi:10.3390/vaccines10081330 · Cited by 14 · see citing works

Fiber modifications enable fowl adenovirus 4 vectors to transduce human cells

Zhang, W., Guo, X., Yin, F., Zou, X., Hou, W., & Lu, Z. (2021) · The Journal of Gene Medicine · doi:10.1002/jgm.3368 · Cited by 14 · see citing works

Next-generation biological vector platforms for in vivo delivery of genome editing agents

Leclerc, D., Siroky, M. D., & Miller, S. M. (2023) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2023.103040 · Cited by 15 · see citing works

Bioprocessing and the Production of Antiviral Biologics in the Prevention and Treatment of Viral Infectious Disease

Meade, E., Rowan, N. J., & Garvey, M. (2023) · Vaccines · doi:10.3390/vaccines11050992 · Cited by 11 · see citing works

Suppression of hepatitis B virus antigen production and replication by wild-type HBV dependently replicating HBV shRNA vectors in vitro and in vivo

Li, B., Sun, S., Li, M., Cheng, X., Li, H., Kang, F., Kang, J., Dörnbrack, K., Nassal, M., & Sun, D. (2016) · Antiviral Research · doi:10.1016/j.antiviral.2016.08.007 · Cited by 11 · see citing works

Small-size recombinant adenoviral hexon protein fragments for the production of virus-type specific antibodies

Pačesa, M., Hendrickx, R., Bieri, M., Flatt, J. W., Greber, U. F., & Hemmi, S. (2017) · Virology Journal · doi:10.1186/s12985-017-0822-5 · Cited by 11 · see citing works

Crystal structure of the fibre head domain of bovine adenovirus 4, a ruminant atadenovirus

Nguyen, T. H., Vidovszky, M. Z., Ballmann, M. Z., Sanz‐Gaitero, M., Singh, A. K., Balázs Harrach, B., Benkő, M., & van Raaij, M. J. (2015) · Virology Journal · doi:10.1186/s12985-015-0309-1 · Cited by 10 · see citing works

Xenogenic Adenoviral Vectors

Mittal, S. K., Ahi, Y. S., & Vemula, S. V. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-800276-6.00019-x · Cited by 9 · see citing works

Upstream Bioprocess for Adenovirus Vectors

Fernandes, P., Silva, A. C., Coroadinha, A. S., & Alves, P. M. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-800276-6.00006-1 · Cited by 8 · see citing works

Encapsulation of Adenovirus BMP2-Transduced Cells with PEGDA Hydrogels Allows Bone Formation in the Presence of Immune Response

Alvarez, P., Davis, E. L., Sonnet, C., Henslee, G., Gugala, Z., Strecker, E. V., Linscheid, L. J., Cuchiara, M. L., West, J. L., Davis, A. R., et al. (2016) · Tissue Engineering Part A · doi:10.1089/ten.tea.2016.0277 · Cited by 8 · see citing works

Optoelectronic control of cardiac rhythm: Toward shock‐free ambulatory cardioversion of atrial fibrillation

Portero, V., Deng, S., Boink, G. J. J., Zhang, G., de Vries, A. A. F., & Pijnappels, D. A. (2023) · Journal of Internal Medicine · doi:10.1111/joim.13744 · Cited by 8 · see citing works

Immunoinformatic construction of an adenovirus-based modular vaccine platform and its application in the design of a SARS-CoV-2 vaccine

Porto, P. S., dos Anjos, D. C. C., Dábilla, N., Fonseca, S. G., & Souza, M. B. L. D. (2020) · Infection Genetics and Evolution · doi:10.1016/j.meegid.2020.104489 · Cited by 7 · see citing works

CELO Fiber1 Knob Is a Promising Candidate to Modify the Tropism of Adenoviral Vectors

Sun, Y., Zou, X., Guo, X., Yang, C., Hung, T., & Lu, Z. (2022) · Genes · doi:10.3390/genes13122316 · Cited by 5 · see citing works

Plasma from some cancer patients inhibits adenoviral Ad5f35 vector transduction of dendritic cells

Jin, P., Chen, W., Ren, J., Chen, S., Wood, L. V., Zhao, Y., Remaley, A. T., Pham, C., Lian, S., Liu, S., et al. (2018) · Cytotherapy · doi:10.1016/j.jcyt.2018.03.001 · Cited by 5 · see citing works

Cancer Gene Therapy

Akbulut, H., Ocal, M., & Sonugur, G. (2015) · InTech eBooks · doi:10.5772/61775 · Cited by 44 · see citing works

Adenovirus as Tools in Animal Health

Rojas, J. M., Sevilla, N., & Martı́n, V. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.79132 · Cited by 5 · see citing works

Antibodies against Adenoviruses

Byrnes, A. P. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-800276-6.00015-2 · Cited by 4 · see citing works

Engineered Sleeping Beauty Transposon as Efficient System to Optimize Chimp Adenoviral Production

Baldassarri, S., Benati, D., D’Alessio, F., Patrizi, C., Cattin, E., Gentile, M., Raggioli, A., & Recchia, A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23147538 · Cited by 3 · see citing works

The future of interleukin gene therapy in head and neck cancers

Hoch, C. C., Hachani, K., Han, Y., Schmidl, B., Wirth, M., Multhoff, G., Dezfouli, A. B., & Wollenberg, B. (2024) · Expert Opinion on Biological Therapy · doi:10.1080/14712598.2024.2405568 · Cited by 3 · see citing works

Characterization of monkey adenoviruses with three fiber genes

Podgorski, I. I., Balázs Harrach, B., Benkő, M., & Papp, T. (2023) · Infection Genetics and Evolution · doi:10.1016/j.meegid.2023.105403 · Cited by 2 · see citing works

Methods to Mitigate Immune Responses to Adenoviral Vectors

Aldhamen, Y. A., & Amalfitano, A. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-800276-6.00016-4 · Cited by 2 · see citing works

Adenovirus Vectors

Ayalew, L. E., Gaba, A., Wang, W., & Tikoo, S. K. (2020) · Springer eBooks · doi:10.1007/978-3-030-51927-8_5 · Cited by 2 · see citing works

Generation of mRNA Vaccine: An Analysis of Two Types of Vectors

Ohanube, G. A. K., & Obeta, U. M. (2021) · International Journal of Pharmaceutical and Phytopharmacological Research · doi:10.51847/0nhpnuouhg · Cited by 2 · see citing works

Oncolytic Bacterial and Viral Therapies as Cancer Prevention and Treatment Options: A Comprehensive Review

Ghalavand, M., Parandin, F., Lutfi, E., Lotfi, H., Yazdi, N. S., Dorostkar, R., Farzanehpour, M., & Ghaleh, H. E. G. (2022) · Iranian Red Crescent Medical Journal · doi:10.32592/ircmj.2022.24.8.1990 · Cited by 2 · see citing works

Why Acute Inflammatory Response Can Happen After Adenoviral Vector Vaccines; Is the Interleukin 6 the Secret and How Circumvent that, Is by Adding Polyethylene Glycol (PEG)?

Ahmed, A. K. K., Shora, H., Mohamed, A. A. M., & Ibrahim, S. (2021) · Acta Scientific Medical Sciences · doi:10.31080/asms.2020.05.0953 · Cited by 2 · see citing works

Transfection of Cultured Primary Neurons

Rossi, A., Dahm, R., & Macchi, P. (2017) · Neuromethods · doi:10.1007/978-1-4939-7024-7_4 · Cited by 1 · see citing works

Immunogenicity of Rabies Virus G-Protein mRNA Formulated with Muscle-Targeting Lipid Nanoparticles in Mice

Li, Q., Bai, H., Yu, X., Liu, Q., & Hu, R. (2025) · Vaccines · doi:10.3390/vaccines13030217 · Cited by 1 · see citing works

Animal Models of Gene Therapy for Cardiovascular Disease

Laakkonen, J. P., & Ylä‐Herttuala, S. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-800276-6.00028-0

A systemically-delivered stem cell therapy for dry age related macular degeneration

Pay, S. L. (2017) · IUScholarWorks (Indiana University) · doi:10.7912/c2006q

Why acute inflammatory response can happen after Adenoviral Vector Vaccines; Is the interleukin 6 the secret and how circumvent that, Is by adding polyethylene glycol (PEG)?Preprint

Ahmed, A. K. K., Shora, H., Mohamed, A. A. M., & Ibrahim, S. (2021) · doi:10.14293/s2199-1006.1.sor-.ppyj404.v1

Faculty Opinions recommendation of Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, and Toxoplasma gondii challenges with a single dose.

Tomalia, D. A. (2019) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.726487211.793560191

Gene Therapy on Cancer Diseases

Khan, Z., & Maske, A. P. (2024) · International Journal of Advanced Research in Science Communication and Technology · doi:10.48175/ijarsct-22733

Utility of adenoviral vectors in animal models—CV disease

Laakkonen, J. P., & Ylä‐Herttuala, S. (2025) · Elsevier eBooks · doi:10.1016/b978-0-323-89821-8.00022-x

Xenogenic adenoviral vectors as vaccines

Coughlan, L. (2025) · Elsevier eBooks · doi:10.1016/b978-0-323-89821-8.00016-4

Comparative Analysis of Two Vector Systems in mRNA Vaccine Development

Ohanube, G. A. K., & Obeta, U. M. (2021) · Interdisciplinary Research in Medical Sciences Specialty · doi:10.51847/xcjuchjjzh

Séroprévalence des anticorps neutralisants dirigés contre les adénovirus de types C5, D26 et B35 au Burkina Faso et au Tchad : impacts sur l’utilisation de vecteurs dérivés des Adénovirus dans un contexte de vaccination

Ouoba, T. (2021) · doi:10.70675/2191bb60zcd55z42a3zb9ddz096fdace9d13

Porcine Adenovirus-Based Viral Vectors for Swine Vaccines: A Scoping Review and Future Perspectives

Sthitmatee, N., Suanpat, K., Sington, Y., Muenthaisong, A., Sangkakam, K., Nambooppha, B., Rittipornlertrak, A., Apinda, N., Koonyosying, P., Varinrak, T., et al. (2026) · Animals · doi:10.3390/ani16203247

Development of nonhuman adenoviruses as vaccine vectors

Bangari, D. S., & Mittal, S. K. (2005) · Vaccine · doi:10.1016/j.vaccine.2005.08.101 · Cited by 142 · see citing works

Adenoviral Vector Immunity: Its Implications and Circumvention Strategies

Ahi, Y. S., Bangari, D. S., & Mittal, S. K. (2011) · Current Gene Therapy · doi:10.2174/156652311796150372 · Cited by 190 · see citing works

Ovine Adenovirus Vectors Overcome Preexisting Humoral Immunity against Human Adenoviruses In Vivo

Hofmann, C., Löser, P., Cichon, G., Arnold, W., Both, G. W., & Strauss, M. (1999) · Journal of Virology · doi:10.1128/jvi.73.8.6930-6936.1999 · Cited by 108 · see citing works

Circumvention of Vector-Specific Neutralizing Antibody Response by Alternating Use of Human and Non-Human Adenoviruses: Implications in Gene Therapy

Moffatt, S., Hays, J. P., HogenEsch, H., & Mittal, S. K. (2000) · Virology · doi:10.1006/viro.2000.0350 · Cited by 100 · see citing works

Current Strategies and Future Directions for Eluding Adenoviral Vector Immunity

Bangari, D. S., & Mittal, S. K. (2006) · Current Gene Therapy · doi:10.2174/156652306776359478 · Cited by 154 · see citing works