The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
The Relationship Between Powder Inhaler Resistance and Peak Inspiratory Conditions in Healthy Volunteers — Implications for In Vitro Testing
Abstract
Despite the fact that powder inhaler devices have been available for over 3 decades there is still very little fundamental information as to how powder inhaler design interacts with the airway dynamics of patients. This paper documents the results of human volunteer investigations designed to elucidate this interaction. These data indicates that if 'maximum' inhalation effort is employed the flow rate attained through an inhaler is controlled by the maximum pressure drop developed by the chest muscles. If a moderate or 'comfortable' effort is used, however, the relationship is more complex. An equation for defining the 'respirable fraction' of an inhalation aerosol cloud as a function of inhalation flow rate is also proposed.
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Citations
Cites
Stratospheric sink for chlorofluoromethanes: chlorine atom-catalysed destruction of ozone
Molina, M. J., & Rowland, F. S. (1974) · Nature · doi:10.1038/249810a0 · Cited by 4,332
Dry Powder Aerosols I: A New Powder Inhalation Device
Bell, J. H., Hartley, P. S., & Cox, J. S. G. (1971) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600601028 · Cited by 202
Cited by
Labiris, N. R., & Dolovich, M. B. (2003) · British Journal of Clinical Pharmacology · doi:10.1046/j.1365-2125.2003.01893.x · Cited by 451
Evolution of dry powder inhaler design, formulation, and performance
NEWMAN, S. P., & BUSSE, W. W. (2002) · Respiratory Medicine · doi:10.1053/rmed.2001.1276 · Cited by 340
Choosing inhaler devices for people with asthma: Current knowledge and outstanding research needs
Haughney, J., Price, D., Barnes, N. C., Virchow, J. C., Roche, N., & Chrystyn, H. (2010) · Respiratory Medicine · doi:10.1016/j.rmed.2010.04.012 · Cited by 190
Metadata
- Authors
- CLARK, A. R., & HOLLINGWORTH, A. M.
- Venue
- Journal of Aerosol Medicine
- Publisher
- SAGE Publications
- Published
- 1993-01
- Volume
- 6
- Issue
- 2
- Pages
- 99-110
- ISSN
- 0894-2684 (ISSN-L)
- 1557-9026
- OpenAlex
- W2041601011
- Cited by
- 332
- References
- 2
- FWCI
- 4.61
- Type
- journal article
- Language
- en
- Open access
- closed
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- CLARK, A. R., & HOLLINGWORTH, A. M. (1993). The Relationship Between Powder Inhaler Resistance and Peak Inspiratory Conditions in Healthy Volunteers — Implications for In Vitro Testing. Journal of Aerosol Medicine. https://doi.org/10.1089/jam.1993.6.99
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
