The DOI matches its Crossref record; 108 of the 108 references it cites were found in a registry or an index.
The Prevalence of Metabolic Syndrome in Children: A Systematic Review of the Literature
Abstract
BACKGROUND: Metabolic syndrome has been identified as a condition of childhood relatively recently. The aim in this study was to describe the prevalence of metabolic syndrome in children allowing for differences in metabolic syndrome definitions. METHODS: This was a systematic review of the OVID, EMBASE, and CINAHL databases, capturing details of overall prevalence and prevalence within groups categorized by obesity, gender, age, and ethnicity. RESULTS: In all, 378 studies published since 2003 were identified, and of these 85 papers were included in the present review. When all studies were considered, the median prevalence of metabolic syndrome in whole populations was 3.3% (range 0%-19.2%), in overweight children was 11.9% (range 2.8%-29.3%), and in obese populations was 29.2% (range 10%-66%). Within-study analyses confirmed higher prevalence for obese compared to overweight (P=0.012) and obese compared to nonobese, nonoverweight children (P<0.001). Within-study analyses also revealed higher median metabolic syndrome prevalence for boys compared to girls (5.1% versus 3.0%, P<0.001) and also in older compared with younger children (5.6% versus 2.9%, P=0.001). Limited evidence was found to suggest differences between ethnic groups, and there were insufficient studies to determine whether metabolic syndrome prevalence was increasing over time. CONCLUSIONS: This is the first systematic review of all of the relevant literature. It describes the magnitude of associations between metabolic syndrome and obesity, age, and gender. We find evidence that ethnicity and geography may be important to metabolic syndrome prevalence in children and these associations require further study.
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Role of Insulin Resistance in Human Disease
Reaven, G. M. (1988) · Diabetes · doi:10.2337/diab.37.12.1595 · Cited by 12,154
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The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men
Lakka, H.-M. (2002) · JAMA · doi:10.1001/jama.288.21.2709 · Cited by 5,033
Banting lecture 1988. Role of insulin resistance in human disease
Reaven, G. M. (1988) · Diabetes · doi:10.2337/diabetes.37.12.1595 · Cited by 3,811
Obesity and the Metabolic Syndrome in Children and Adolescents
Weiss, R., Dziura, J., Burgert, T. S., Tamborlane, W. V., Taksali, S. E., Yeckel, C. W., Allen, K., Lopes, M., Savoye, M., Morrison, J., et al. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa031049 · Cited by 3,459
Childhood obesity: public-health crisis, common sense cure
Ebbeling, C. B., Pawlak, D. B., & Ludwig, D. S. (2002) · The Lancet · doi:10.1016/s0140-6736(02)09678-2 · Cited by 2,980
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Novel Insights into the Pathogenesis and Management of the Metabolic Syndrome
Wang, H. H., Lee, D. K., Liu, M., Portincasa, P., & Wang, D. Q.-H. (2020) · Pediatric Gastroenterology, Hepatology & Nutrition · doi:10.5223/pghn.2020.23.3.189 · Cited by 281
Early-life exposure to perfluoroalkyl substances and childhood metabolic function
Fleisch, A. F., Rifas-Shiman, S. L., Mora, A. M., Calafat, A. M., Ye, X., Luttmann-Gibson, H., Gillman, M. W., Oken, E., & Sagiv, S. K. (2017) · Environmental Health Perspectives · doi:10.1289/ehp303 · Cited by 91
Tanvig, M., Vinter, C. A., Jørgensen, J. S., Wehberg, S., Ovesen, P. G., Beck-Nielsen, H., Christesen, H. T., & Jensen, D. M. (2015) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2014-2675 · Cited by 77
Yackobovitch‐Gavan, M., Wolf Linhard, D., Nagelberg, N., Poraz, I., Shalitin, S., Phillip, M., & Meyerovitch, J. (2018) · Pediatric Obesity · doi:10.1111/ijpo.12263 · Cited by 50
Herouvi, D., Vlachopapadopoulou, E. A., Vakaki, M., Gouriotis, D., Marmarinos, A., Kalpia, C., Kossiva, L., Tsolia, M., & Karavanaki, K. (2024) · Endocrine · doi:10.1007/s12020-024-04139-x · Cited by 5
Metadata
- Authors
- Friend, A., Craig, L., & Turner, S.
- Venue
- Metabolic Syndrome and Related Disorders
- Publisher
- SAGE Publications
- Published
- 2013-04
- Volume
- 11
- Issue
- 2
- Pages
- 71-80
- ISSN
- 1540-4196 (ISSN-L)
- 1557-8518
- OpenAlex
- W1996835915
- Cited by
- 354
- References
- 108
- FWCI
- 2.09
- Type
- journal article
- Language
- en
- Open access
- closed
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