Predictors of very-long-term sociocognitive function after pediatric traumatic brain injury: evidence for the vulnerability of the immature “social brain”
Abstract
Emotion perception (EP) forms an integral part of social communication and is critical to attain developmentally appropriate goals. This skill, which emerges relatively early in development, is driven by increasing connectivity among regions of a distributed sociocognitive neural network and may be vulnerable to disruption from early-childhood traumatic brain injury (TBI). The present study aimed to evaluate the very-long-term effect of childhood TBI on EP, as well as examine the contribution of injury- and non-injury-related risk and resilience factors to variability in sociocognitive outcomes. Thirty-four young adult survivors of early-childhood TBI (mean [M], 20.62 years; M time since injury, 16.55 years) and 16 typically developing controls matched for age, gender, and socioeconomic status were assessed using tasks that required recognition and interpretation of facial and prosodic emotional cues. Survivors of severe childhood TBI were found to have significantly poorer emotion perception than controls and young adults with mild-to-moderate injuries. Further, poorer emotion perception was associated with reduced volume of the posterior corpus callosum, presence of frontal pathology, lower SES, and a less-intimate family environment. Our findings lend support to the vulnerability of the immature "social brain" network to early disruption and underscore the need for context-sensitive rehabilitation that optimizes early family environments to enhance recovery of EP skills after childhood TBI.
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Two main findings-that TBI was associated with subsequent adverse adulthood outcomes, and the dose-response relationship with injury severity-are consistent with previous research.
“Two main findings—that TBI was associated with subsequent adverse adulthood outcomes, and the dose-response relationship with injury severity—are consistent with previous research [17–20,44]”
Cites
Tabachnick, B. G., & Fidell, L. S. (1983) · Cited by 79,888 · see citing works
Dynamic mapping of human cortical development during childhood through early adulthood
Gogtay, N., Giedd, J. N., Lusk, L., Hayashi, K. M., Greenstein, D., Vaituzis, A. C., Nugent, T. F., Herman, D. H., Clasen, L. S., Toga, A. W., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402680101 · Cited by 5,604 · cited 13× · see citing works
“In our sample of 34 young adult survivors of early-childhood TBI, EP was related to injury-related risk factors; including injury SOCIOCOGNITIVE FUNCTION POST-PEDIATRIC TBI severity, posterior CC volume, and frontal pathology as well as environmental factors, including SES and family intimacy, that may represent sourc…”
InfluentialBrain development during childhood and adolescence: a longitudinal MRI study
Giedd, J. N., Blumenthal, J., Jeffries, N. O., Castellanos, F. X., Liu, H., Zijdenbos, A., Paus, T., Evans, A. C., & Rapoport, J. L. (1999) · Nature Neuroscience · doi:10.1038/13158 · Cited by 5,552 · see citing works
The neurobiology of social cognition
Adolphs, R. (2001) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(00)00202-6 · Cited by 1,432 · see citing works
WITELSON, S. F. (1989) · Brain · doi:10.1093/brain/112.3.799 · Cited by 1,424 · see citing works
Adolphs, R., Damasio, H., Tranel, D., Cooper, G., & Damasio, A. R. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-07-02683.2000 · Cited by 1,095 · see citing works
Functional brain development in humans
Johnson, M. H. (2001) · Nature Reviews Neuroscience · doi:10.1038/35081509 · Cited by 980 · see citing works
Mcdonald (2003) · doi:10.1097/00001199-200305000-00001 · Cited by 657 · see citing works
SOCIAL: An integrative framework for the development of social skills.
Beauchamp, M. H., & Anderson, V. A. (2010) · Psychological Bulletin · doi:10.1037/a0017768 · Cited by 647 · see citing works
Self-citationDo children really recover better? Neurobehavioural plasticity after early brain insult
Anderson, V. A., Spencer‐Smith, M. M., & WOOD, A. G. (2011) · Brain · doi:10.1093/brain/awr103 · Cited by 587 · see citing works
Self-citationTraumatically Induced Axonal Injury: Pathogenesis and Pathobiological Implications
Povlishock, J. (1991) · Brain Pathology · doi:10.1111/j.1750-3639.1991.tb00050.x · Cited by 475 · see citing works
Yeates, K. O., Bigler, E. D., Dennis, M., Gerhardt, C. A., Rubin, K. H., Stancin, T., Taylor, H. G., & Vannatta, K. A. (2007) · Psychological Bulletin · doi:10.1037/0033-2909.133.3.535 · Cited by 445 · see citing works
Short- and long-term social outcomes following pediatric traumatic brain injury
YEATES, K. O., SWIFT, E., TAYLOR, H. G., WADE, S. L., DROTAR, D., STANCIN, T., & MINICH, N. (2004) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617704103093 · Cited by 421 · see citing works
Traumatically induced axonal injury: pathogenesis and pathobiological implications.
Povlishock, J. T. (1992) · PubMed · Cited by 420 · see citing works
Annual Research Review: Parenting and children’s brain development: the end of the beginning
Belsky, J., & de Haan, M. D. H. (2010) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2010.02281.x · Cited by 397 · see citing works
The emergence of the social brain network: evidence from typical and atypical development
JOHNSON, M. H., GRIFFIN, R., CSIBRA, G., HALIT, H., FARRONI, T., DE HAAN, M., TUCKER, L. A., BARON–COHEN, S., & RICHARDS, J. (2005) · Development and Psychopathology · doi:10.1017/s0954579405050297 · Cited by 369 · see citing works
Yeates, K. O., Taylor, H. G., Drotar, D., Wade, S. L., Klein, S. K., Stancin, T., & Schatschneider, C. W. (1997) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617797006176 · Cited by 307 · see citing works
Pediatric Neuropsychology : Research, Theory, and Practice
Yeates, K. O., Ris, M. D., & Taylor, H. G. (1999) · Cited by 295 · see citing works
McDonald, S., & Flanagan, S. (2004) · Neuropsychology · doi:10.1037/0894-4105.18.3.572 · Cited by 277 · see citing works
Milders, M. M., Fuchs, S. C. P. C., & Crawford, J. R. (2003) · Journal of Clinical and Experimental Neuropsychology · doi:10.1076/jcen.25.2.157.13642 · Cited by 274 · see citing works
Yeates, K. O., Taylor, H. G., Walz, N. C., Stancin, T., & Wade, S. L. (2010) · Neuropsychology · doi:10.1037/a0018387 · Cited by 260 · see citing works
Braga, L. W., Júnior, A. C. D. P., & Ylvisaker, M. (2005) · Brain Injury · doi:10.1080/02699050500110165 · Cited by 240 · see citing works
Wilde, E. A., Hunter, J. V., Newsome, M. R., Scheibel, R. S., Bigler, E. D., Johnson, J. L., Fearing, M. A., Cleavinger, H. B., Li, X., Swank, P. R., et al. (2005) · Journal of Neurotrauma · doi:10.1089/neu.2005.22.333 · Cited by 217 · see citing works
Words Speak Louder Than Actions: Understanding Deliberately False Remarks
Demorest, A. P., Meyer, C., Phelps, E., Gardner, H., & Winner, E. (1984) · Child Development · doi:10.2307/1130022 · Cited by 208 · see citing works
Bornhofen, C., & McDonald, S. (2008) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617708080703 · Cited by 184 · see citing works
Tonks, J., Williams, W. H., Frampton, I. J., et al. (2007) · Brain Injury · doi:10.1080/02699050701426865 · Cited by 175 · see citing works
Ewing‐Cobbs, L., Prasad, M. R., Swank, P. R., Kramer, L. A., Cox, C. S., Fletcher, J. M., Barnes, M. A., Zhang, X., & Hasan, K. M. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.06.031 · Cited by 166 · see citing works
Spikman, J. M., Timmerman, M. E., Milders, M. V., Veenstra, W. S., & van der Naalt, J. (2011) · Journal of Neurotrauma · doi:10.1089/neu.2011.2084 · Cited by 165 · see citing works
Deficits in facial emotion perception in adults with recent traumatic brain injury
Green, R. (2003) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2003.07.005 · Cited by 145 · see citing works
Pediatric Neuropsychology: Research, Theory, and Practice
Desira, F., & Lovell, M. (2011) · Child and Adolescent Mental Health · doi:10.1111/j.1475-3588.2011.00625_1.x · Cited by 135 · see citing works
Knox, L., & Douglas, J. M. (2008) · Brain and Cognition · doi:10.1016/j.bandc.2008.09.009 · Cited by 132 · see citing works
Social Information Processing in Adolescents
Turkstra, L. S., McDonald, S., & DePompei, R. (2001) · Journal of Head Trauma Rehabilitation · doi:10.1097/00001199-200110000-00006 · Cited by 112 · see citing works
Noller, P., Seth‐Smith, M., Bouma, R., et al. (1992) · Journal of Adolescence · doi:10.1016/0140-1971(92)90041-3 · Cited by 112 · see citing works
Longitudinal aspects of emotion recognition in patients with traumatic brain injury
Ietswaart, M., Milders, M. M., Crawford, J. R., Currie, D. G., & Scott, C. L. (2007) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2007.08.002 · Cited by 109 · see citing works
Recovery of memory function following traumatic brain injury in pre-school children
Vicki A. Anderson, C. C. (2000) · Brain Injury · doi:10.1080/026990500413704 · Cited by 107 · see citing works
Reduction of corpus callosum growth after severe traumatic brain injury in children
Levin, H. S., Benavidez, D. A., Verger-Maestre, K., Perachio, N., Song, J., Mendelsohn, D. B., & Fletcher, J. M. (2000) · Neurology · doi:10.1212/wnl.54.3.647 · Cited by 103 · see citing works
León‐Carrión, J., & Ramos, F. J. C. (2003) · Brain Injury · doi:10.1080/0269905021000010249 · Cited by 101 · see citing works
Traumatic brain injury among Australian prisoners: Rates, recurrence and sequelae
Schofield, P. W., Butler, T. G., Hollis, S. J., Smith, N. E., Lee, S. J., & Kelso, W. M. (2006) · Brain Injury · doi:10.1080/02699050600664749 · Cited by 99 · see citing works
Interpreting facial expression and communication competence following severe traumatic brain injury
Watts, A., & Douglas, J. M. (2006) · Aphasiology · doi:10.1080/02687030500489953 · Cited by 79 · see citing works
How Children with Head Injury Represent Real and Deceptive Emotion in Short Narratives
Dennis, M., Barnes, M. A., Wilkinson, M., & Humphreys, R. P. (1998) · Brain and Language · doi:10.1006/brln.1997.1886 · Cited by 76 · see citing works
Holdnack, J. A., Goldstein, G., & Drozdick, L. W. (2011) · Assessment · doi:10.1177/1073191110394771 · Cited by 70 · see citing works
Tonks, J., Williams, W. H., Frampton, I. J., Yates, P., & Slater, A. M. (2007) · Brain Injury · doi:10.1080/02699050701426899 · Cited by 69 · see citing works
Schmidt, A., Hanten, G. R., Li, X., Orsten, K. D., & Levin, H. S. (2010) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2010.05.029 · Cited by 68 · see citing works
Benavidez, D. A., Fletcher, J. M., Hannay, H. J., et al. (1999) · Cortex · doi:10.1016/s0010-9452(08)70803-7 · Cited by 67 · see citing works
Vulnerability of the Anterior Commissure in Moderate to Severe Pediatric Traumatic Brain Injury
Wilde, E. A., Bigler, E. D., Haider, J. M., Chu, Z. D., Levin, H. S., Li, X., & Hunter, J. V. (2006) · Journal of Child Neurology · doi:10.1177/08830738060210090201 · Cited by 62 · see citing works
Head Circumference and Brain and Hippocampal Volume after Severe Traumatic Brain Injury in Childhood
Tasker, R. C., Salmond, C. H., Westland, A. G., Peña, A., Gillard, J. H., Sahakian, B. J., & Pickard, J. D. (2005) · Pediatric Research · doi:10.1203/01.pdr.0000169965.08854.25 · Cited by 60 · see citing works
Developmental Trajectories of the Corpus Callosum in Attention-Deficit/Hyperactivity Disorder
Gilliam, M., Stockman, M., Malek, M., Sharp, W., Greenstein, D., Lalonde, F., Clasen, L., Giedd, J., Rapoport, J., & Shaw, P. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.11.024 · Cited by 56 · see citing works
Dimoska, A., McDonald, S., Pell, M. D., Tate, R. L., & James, C. (2010) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617709991445 · Cited by 56 · see citing works
Sengpiel, F. (2007) · Current Biology · doi:10.1016/j.cub.2007.06.017 · Cited by 53 · see citing works
Impairment in the recognition of emotion across different media following traumatic brain injury
Williams, C., & Wood, R. L. (2009) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/13803390902806543 · Cited by 48 · see citing works
Extent and Distribution of Vascular Brain Injury in Pediatric Road Fatalities
Gorrie, C. A., Duflou, J. A., Brown, J. K., Gibson, T., & Waite, P. M. E. (2001) · Journal of Neurotrauma · doi:10.1089/089771501750451776 · Cited by 28 · see citing works
Emotion Labeling and Socio-Emotional Outcomes 18 Months after Early Childhood Traumatic Brain Injury
Tlustos, S. J., Chiu, C.-Y. P., Walz, N. C., Taylor, H. G., Yeates, K. O., & Wade, S. L. (2011) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617711001202 · Cited by 26 · see citing works
Family environment influences emotion recognition following paediatric traumatic brain injury
Schmidt, A., Orsten, K. D., Hanten, G. R., Li, X., & Levin, H. S. (2010) · Brain Injury · doi:10.3109/02699052.2010.523047 · Cited by 24 · see citing works
Tonks, J., Williams, W. H., Frampton, I. J., Yates, P., & Slater, A. M. (2007) · Brain Impairment · doi:10.1375/brim.8.2.143 · Cited by 18 · see citing works
Focal thinning of the posterior corpus callosum: Normal variant or post-traumatic?
Beauchamp, M. H., Ditchfield, M. R., Catroppa, C., et al. (2011) · Brain Injury · doi:10.3109/02699052.2011.589791 · Cited by 17 · see citing works
Self-citationICPS Family Functioning Scales
Noller, P. (1988) · PsycTESTS Dataset · doi:10.1037/t26345-000 · Cited by 14 · see citing works
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Sariaslan, A., Sharp, D. J., D’Onofrio, B. M., Larsson, H., & Fazel, S. (2016) · PLOS Medicine · doi:10.1371/journal.pmed.1002103 · Cited by 262 · see citing works
“Previous work suggests that TBI in children contributes to poorer measures of emotion perception and social interaction [17,18], employment, and quality of life [19,20].”
Background
- Authors
- Ryan, N. P., Anderson, V., Godfrey, C., Beauchamp, M. H., Coleman, L., Eren, S., Rosema, S., Taylor, K., & Catroppa, C.
- Affiliations
- The University of Melbourne (AU)
- Royal Children's Hospital (AU)
- CHU Sainte-Justine Research Center (CA)
- Murdoch Children's Research Institute (AU)
- Corresponding author
- Ryan, Nicholas P.
- ORCID
- Venue
- Journal of Neurotrauma
- Publisher
- SAGE Publications
- Published
- 2014-04
- Volume
- 31
- Issue
- 7
- Pages
- 649-657
- ISSN
- 0897-7151 (ISSN-L)
- 1557-9042
- OpenAlex
- W1968002435
- Cited by
- 107
- References
- 56
- Citations by year
- 2026: 3 · 2025: 1 · 2024: 11 · 2023: 4 · 2022: 11 · 2021: 15 · 2020: 8 · 2019: 8 · 2018: 9 · 2017: 11 · 2016: 9 · 2015: 12 · 2014: 4
- FWCI
- 6.07
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Neurotrauma (publishedVersion)
- PubMed (publishedVersion)
- Funders
- State Government of Victoria
- National Health and Medical Research Council
- National Medical Research Council
- Topics
- Health Sciences › Medicine › Epidemiology › Traumatic Brain Injury Research
- Health Sciences › Medicine › Neurology › Traumatic Brain Injury and Neurovascular Disturbances
- Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
- Keywords
- pediatric traumatic brain injury, emotion perception, social brain network, corpus callosum volume, frontal lobe pathology, socioeconomic status, family environment, resilience factors, facial emotion recognition, long-term outcomes, young adults
- MeSH terms
- Brain Injuries, Child, Female, Humans, Male, Neuropsychological Tests, Survivors, Young Adult, Emotional Intelligence
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