From personalized medicine to personalized science: uniting science and medicine for patient-driven, goal-oriented research
Abstract
We developed a new model for initiating, coordinating, funding, and managing biomedical research projects. The concept involves engaging the patients with chronic conditions with no known cures into goal-oriented research activities. In this model, the patient seeks the help of a research organization to bring together a multidisciplinary team of research scientists and physicians to initiate research projects using the patient's grant funding, samples, as well as the management expertise. This model may be of interest to other research institutions because it has many benefits, including new sources of private research funding, when government funding is getting scarce, motivating scientists and physicians to work closely together on goal- and patient-oriented research projects, and using patients' management skills.
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None of the recent approaches to personalized medicine in oncology and other diseases are truly integrative on the population scale and compare the predictive nature and value of the various data types in the context of biomedicine.
“none of these approaches are truly integrative on the population scale and compare the predictive nature and value of the various data types in the context of biomedicine.”
From Converging blockchain and next-generation artificial intelligence technologies to decentralize and accelerate biomedical research and healthcare (2018) · cites this paper as [25]
Cites
Martinson, B. C., Anderson, M. S., & de Vries, R. (2005) · Nature · doi:10.1038/435737a · Cited by 1,096 · see citing works
Physicians in retainer (“Concierge”) practice
Alexander, G. C., Kurlander, J. E., & Wynia, M. K. (2005) · Journal of General Internal Medicine · doi:10.1111/j.1525-1497.2005.0233.x · Cited by 67 · see citing works
Luxury Primary Care — Market Innovation or Threat to Access?
Brennan, T. A. (2002) · New England Journal of Medicine · doi:10.1056/nejm200204113461513 · Cited by 35 · see citing works
Luxury primary care, academic medical centers, and the erosion of science and professional ethics
Donohoe, M. (2004) · Journal of General Internal Medicine · doi:10.1111/j.1525-1497.2004.20631.x · Cited by 20 · see citing works
Academic Retainer Medicine: An Innovative Business Model for Cross-Subsidizing Primary Care
Lucier, D. J., Frisch, N. B., Cohen, B. J., Wagner, M., Salem, D. N., & Fairchild, D. G. (2010) · Academic Medicine · doi:10.1097/acm.0b013e3181dbe19e · Cited by 13 · see citing works
Science in History: Volume 1 The Emergence of Science
Bernal, J. D. (1971) · Cited by 12 · see citing works
Concierge care and the future of general internal medicine
Brennan, T. A. (2005) · Journal of General Internal Medicine · doi:10.1111/j.1525-1497.2005.00276.x · Cited by 9 · see citing works
Signing Up for Contract Research And Development
Travis, J. P. (1994) · Science · doi:10.1126/science.265.5180.1915 · Cited by 1 · see citing works
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Mamoshina, P., Ojomoko, L., Yanovich, Y., Ostrovski, A., Botezatu, A., Prikhodko, P., Izumchenko, E., Aliper, A., Romantsov, K., Zhebrak, A., et al. (2018) · Oncotarget · doi:10.18632/oncotarget.22345 · Cited by 471 · see citing works
Self-citation
- Authors
- Zhavoronkov, A., & Cantor, C. R.
- Affiliations
- Moscow Institute of Physics and Technology (RU)
- Boston University (US)
- Corresponding author
- Zhavoronkov, Alex
- ORCID
- Zhavoronkov, Alex
- Venue
- Rejuvenation Research
- Publisher
- SAGE Publications
- Published
- 2013-10
- Volume
- 16
- Issue
- 5
- Pages
- 414-418
- ISSN
- 1094-5458 (ISSN-L)
- 1549-1684
- 1557-8577
- OpenAlex
- W1997683842
- Cited by
- 14
- References
- 8
- Citations by year
- 2025: 1 · 2022: 1 · 2020: 1 · 2017: 1 · 2016: 1 · 2015: 4 · 2014: 5
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Rejuvenation Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health and Medical Research Impacts
- Health Sciences › Health Professions › General Health Professions › Mental Health and Patient Involvement
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ethics in Clinical Research
- Keywords
- personalized medicine, chronic disease, patient engagement, research funding models, patient samples, multidisciplinary research teams, private research funding, research project management
- MeSH terms
- Goals, Humans, Research Support as Topic, Patient-Centered Care, Biomedical Research, Precision Medicine
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