iPSC-Derived Forebrain Neurons from FXS Individuals Show Defects in Initial Neurite Outgrowth
Doers, Matthew E., Musser, Michael T., Nichol, Robert, Berndt, Erich R., Baker, Mei, Gomez, Timothy M., Zhang, Su-Chun, Abbeduto, Leonard, Bhattacharyya, Anita·2014·Stem Cells and Development
Cited by (165)
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- Progress in the molecular mechanisms of genetic epilepsies using patient‐induced pluripotent stem cellsRuijiao Zhou, Guohui Jiang, Xin Tian, Xuefeng Wang · 2018 · Epilepsia Open
- One-Step Generation of Seamless Luciferase Gene Knockin Using CRISPR/Cas9 Genome Editing in Human Pluripotent Stem CellsMeng Li, Jack F.V. Hunt, Anita Bhattacharyya, Xinyu Zhao · 2019 · Methods in molecular biology
- Using Induced Pluripotent Stem Cells to Investigate Complex Genetic Psychiatric DisordersStephanie J. Temme, Brady J. Maher, Kimberly M. Christian · 2016 · Current Behavioral Neuroscience Reports
- Activity of Human-Specific Interlaminar Astrocytes in a Chimeric Mouse Model of Fragile X SyndromeAlexandria Anding, Baiyan Ren, Ragunathan Padmashri, Maria E. Burkovetskaya, Anna Dunaevsky · 2025 · International Journal of Molecular Sciences
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- FMRP Regulates Neurogenesis In Vivo in Xenopus laevis TadpolesRegina L. Faulkner, Tyler J. Wishard, Christopher K. Thompson, Han-Hsuan Liu, Hollis T. Cline · 2015 · eNeuro
- Human Pluripotent Stem Cells in Modeling Human Disorders: the Case of Fragile X SyndromeDan Vershkov, Nissim Benvenisty · 2016 · Regenerative Medicine
- Antisense oligonucleotides to KIF1A polymorphisms expand targets and rescue patient-derived neurons in vitroMichael V. Zuccaro, Randee E. Young, Jiangyuan Hu, Patricia Lanzano, Ekaterina Semenova, Xiaoqi Lin, Alicja A. Skowronski, Yufeng Shen, Tae Hyun Kim, Danny E. Miller et al. · 2026 · Nature Communications
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- Modeling Fragile X Syndrome Using Human Pluripotent Stem CellsDan Vershkov, Tamir Ben‐Hur, Nissim Benvenisty · 2017 · Elsevier eBooks
- Using Human Induced Neural Precursor Cells to Define Early Neurodevelopmental Defects in Syndromic and Idiopathic AutismRobert Connacher, Emanuel M. DiCicco-Bloom, James H. Millonig · 2018 · Current Pharmacology Reports
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- Directly reprogrammed fragile X syndrome dorsal forebrain precursor cells generate cortical neurons exhibiting impaired neuronal maturationNicole Edwards, Catharina Combrinck, Amy McCaughey‐Chapman, Bronwen J. Connor · 2023 · Frontiers in Cellular Neuroscience
- Efficient generation of human induced pluripotent stem cells from urine samples of patients with Fragile X syndromeOlivier Dionne, Salomé Sabatié, Fléchère Fortin, François Corbin, Benoît Laurent · 2024 · Frontiers in Cell and Developmental Biology
- Células madre: limitaciones y oportunidades en el Perú.José Amiel-Pérez, Fanny Lys Casado · 2015 · Revista Peruana de Medicina Experimental y Salud Pública
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- Deep functional measurements of Fragile X syndrome human neurons reveal multiparametric electrophysiological disease phenotypeJames J. Fink, Nathaniel Delaney-Busch, Ryan P. Dawes, Evanthia Nanou, Christopher J. Folts, Karthiayani Harikrishnan, Chris Martin Hempel, Hansini Upadhyay, Trinh Mai Nguyen, Himali Shroff et al. · 2024 · Communications Biology
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- Fragile X Syndrome Patient–Derived Neurons Developing in the Mouse Brain Show FMR1-Dependent PhenotypesMarine Krzisch, Hao Wu, Bingbing Yuan, Troy W. Whitfield, X. Shawn Liu, Dongdong Fu, Carrie M. Garrett-Engele, Andrew S. Khalil, Tenzin Lungjangwa, Jennifer Shih et al. · 2021 · Biological Psychiatry
- Near-cognate initiation generates FMRpolyG from CGG repeats in Fragile X associated Tremor Ataxia SyndromeYuan Zhang, M. R. Glineburg, V. Basrur, K. Conlon, Deborah A. Hall, Peter K. Todd · 2020 · bioRxiv
- Unraveling the Role of Neuroligin3 in Autism Spectrum Disorders: Pathophysiological Insights and Targeted TherapiesFatima Azzahrae El Yacoubi, Mohamed Oukabli, Azeddine Ibrahimi, Hassan Kisra, Mounia Bensaid · 2023 · CNS & Neurological Disorders - Drug Targets
- EZH2 inhibition reactivates epigenetically silenced FMR1 and normalizes molecular and electrophysiological abnormalities in fragile X syndrome neuronsMinggang Fang, Sara K. Deibler, Pranathi Meda Krishnamurthy, Feng Wang, Paola María Rodríguez, Shahid Banday, Ching-Man A. Virbasius, Miguel Sena‐Esteves, Jonathan K. Watts, Michael R. Green · 2024 · Frontiers in Neuroscience
- Human iPSC Models: A Platform for Investigating Neurodevelopmental DiseasesCindy E. McKinney · 2014 · Journal of Molecular and Genetic Medicine
- Brain in a DishCleber A. Trujillo, Priscilla Davidson Negraes, Branka Hrvoj-Mihić, Mauro F.C. Lins, Katerina Semendeferi, Alysson Renato Muotri · 2016 · Elsevier eBooks
- Induced pluripotent stem cells as models of human neurodevelopmental disordersAlexandre Jourdon, Jessica Mariani, Soraya Scuderi, Anahita Amiri, Feinan Wu, Eunice Y. Yuen, Alexej S. Abyzov, Flora Maria Vaccarino · 2020 · Elsevier eBooks
- Stem Cell Epigenetics and Human DiseaseLeila Larijani, Derrick E. Rancourt · 2018 · Elsevier eBooks
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- Psychiatrische Erkrankungen mit Stammzelltechnologien verstehenRicarda Stock, Hansjürgen Volkmer · 2020 · BIOspektrum
- Human pluripotent stem cells in the research of Fragile X SyndromeMichael Telias · 2021 · Elsevier eBooks
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- Human iPSC-Derived Brain Cells, Organoids, and Organoids-on-Chips: Advancing Neurological Disease Modeling to Improve Clinical OutcomeGabriel Burdman, Marco Hanna, Adriana Yndart, Arti Vashist, Madepalli Krishnappa Lakshmana · 2026 · Cells