Development of a Full-Thickness Human Skin Equivalent In Vitro Model Derived from TERT-Immortalized Keratinocytes and Fibroblasts

Reijnders, Christianne M.A., van Lier, Amanda, Roffel, Sanne, Kramer, Duco, Scheper, Rik J., Gibbs, Susan·2015·Tissue Engineering Part A

Cited by (147)

Items 101–147 of 147

  1. Skin-on-Chip
    Deepa Chaturvedi, Sourav Mukherjee, Pooja Sawant, Prajakta Dandekar Jain, Abhijit Majumder · 2022 · Springer eBooks
  2. Highly Porous and Rigid, Full-thickness Human Skin Model from the Slime-webbed Fiber Scaffold
    Jae Jung Kim, Nam Keun Lee, Da Eun Ryu, Byoung Ho Ko, Ju‐Hyeon Kim, Jin‐Kyu Rhee, Jong Hwan Sung · 2023 · Biotechnology and Bioprocess Engineering
  3. Do Melanocytes Have a Role in Controlling Epidermal Bacterial Colonisation and the Skin Microbiome?
    Omera Bi, David Caballero‐Lima, Stephen K. Sikkink, Gillian Elizabeth Westgate, Söbia Kauser, Jacobo Elíes, Margaret Julie Thornton · 2025 · Experimental Dermatology
  4. Establishment and characterization of an immortalized human chondrocyte cell line
    Jia‐Shu Yang, Yuting Tang, Wensun Chen, Ming Zhang, Fangling Hong, Dawei Yang, Qianyi Bao, Ying Yang, Yucui Jin, Lingyun Li et al. · 2020 · Biotechnology Letters
  5. Extending In-Plane Impedance Measurements from 2D to 3D Cultures: Design Considerations
    Sorel E. De León, Lana Cleuren, Zay Yar Oo, Paul R. Stoddart, Sally L. McArthur · 2021 · Bioengineering
  6. Bioengineered Skin Substitutes
    Tanja Zidarič, Karin Stana Kleinschek, Uroš Maver, Tina Maver · 2023 · Springer briefs in molecular science
  7. Comparative analysis of N/TERT-1 and N/TERT-2G keratinocyte responses to oxidative stress and immune challenges
    Sholeem Griffin, Jefferson de Oliveira Mallia, Georgios Psakis, Juan Attard, Matthias Caruana, Ruben Gatt · 2025 · Cellular Signalling
  8. Advancements in in vitro psoriasis models: relevance for drug discovery and therapeutic development
    Devaraj, Deesha Jain, Sandeep Kr Maharana, Pavan Sawant, Aakanchha Jain · 2025 · International Journal of Pharmaceutics
  9. A New Ex Vivo Human Skin Burn Model
    Ania Labouchère, Daniel Haselbach, Murielle Michetti, Catherine Pythoud, Wassim Raffoul, Lee Ann Applegate, Nathalie Hirt‐Burri, Anthony de Buys Roessingh · 2023 · Journal of Burn Care & Research
  10. Evaluating blue light impact on reconstructed human epidermis using laser speckle imaging
    Léa Habib, Léa Abi Nassif, Marie Abboud, Rime Michael‐Jubeli, Ali M. Tfayli, Roger Lteif · 2025 · Journal of Biomedical Optics
  11. Generation of Pigmented Skin Grafts from Human Hair Follicles and Dermal Fibroblasts
    Marie Schneider, Mirjana Ziemer, Bernd Lethaus, Jan Christoph Simon, Vuk Savković · 2021 · Tissue Engineering Part A
  12. Skin-on-a-Chip Coupled with a Rapid Inflammation Detection System for Cosmetic Ingredient Screening
    Zijia Liu, Biao Wu, Yidong Tu, Tianbi Duan, Kang Cheng, Zhi Lv, Ruixue Yin, Honglin Li, Hongbo Zhang · 2024 · Biomedical Materials & Devices
  13. Development of Human Skin Equivalents with Inducible Ceramide Depletion for In Vitro Modeling of Lipid Impairment
    Durotimi O Dina, Miriam Maiellaro, Emanuela Camera, John T. Connelly · 2025 · JID Innovations
  14. Skin irritation testing using human iPSCs derived 3D skin equivalent model
    Hyewon Shin, Se-Eun Kim, C‐Yoon Kim, Suemin Lee, Ji-Heon Lee, Jieun Baek, Gujin Chung, Min Woo Kim, Jeong-Seop Oh, Shinhye Park et al. · 2025 · PLoS ONE
  15. Dynamic biomimicry in skin-on-a-chip: multi-scale construction to translational dermatology, drug screening and cosmetic evaluation
    Linwei Sang, Ajing Liu, Haochen Wang, W.L. Li, Qin Tu, Jinyi Wang · 2026 · Lab on a Chip
  16. Engineering a Pigmented Skin Equivalent That Is Responsive to External Stimuli
    Paola De Los Santos Gomez, Kirsty Goncalves, Victoria Maltman, Lucy A. Smith, Stefan Alexander Przyborski · 2025 · Methods in molecular biology
  17. Skin-on-a-Chip Microfluidic Devices: Production, Verification, and Uses in Cosmetic Toxicology
    Krishan Mistry, Michael H. Alexander · 2023 · Springer eBooks
  18. Advances in research methods for the mechanisms of transdermal drug absorption
    Weijia Liu, Mengjun Pan, Shuo Pan, Wanqing Dai, Zhengguang Li, Xiaoqin Chu · 2026 · Journal of Drug Delivery Science and Technology
  19. Bioenergetic profiling in the skin
    Daniel H. González Maglio, Timoteo Marchini, Eliana M. Cela, Natalia Magnani, Juliana Leoni, Mariela Laura Paz, Pablo Evelson · 2020 · Elsevier eBooks
  20. An automated high-throughput platform for experimental study of burn injuries - in vitro and ex vivo
    Nir Melnikov, Pascal Kobel, Tahir Detinis Zur, Ayelet Di Segni, Yael Leichtmann‐Bardoogo, Josef Haik, Ben Meir Maoz · 2022 · Burns
  21. Advances in skin-on-a-chip and skin tissue engineering
    Alberto Pappalardo, Alvarez Cespedes, Ha Linh Vu, Hasan Erbil Abaci · 2023 · Elsevier eBooks
  22. Effect of Adenovirus-mediated Decorin Gene Therapy on Fibrotic Remodeling in Tissue-engineered Skin
    Saahil Sanon · 2016 · ERA: Education and Research Archive (University of Alberta)
  23. Controlling fibroblast fibrinolytic activity allows for the bio-engineering of stable connective tissue equivalents
    Elea Boucard, Flora Coulon, Luciano Vidal, Jean-Yves Hascoët, Carlos Mota, Franck Albert Halary · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  24. Nanoparticules biodégradables et multifonctionnelles pour la régénération tissulaire de plaies cutanées profondes
    Morgane Berthet · 2017
  25. Vascularized human skin assembloids model compartmental skin organization and immune responsiveness in vitro
    Kim, Min-Ji, Lee, Seunghee, Kang, Kyung-Sun · 2026 · Experimental & Molecular Medicine
  26. Preclinical Models for Drug Screening and Target Validation
    Ivo J. H. M. de Vos, Julia Verbist, Maurice A. M. Van Steensel · 2019 · Wiley eBooks
  27. Evaluation of different models of tumor spheroid generation with CAL27 cells
    Leilane de Sousa Mendonça, Laura Luiza Moreira da Silva Dias, Herick Henrique Ferreira Koolen, Émerson Silva Lima, Marne Carvalho de Vasconcellos · 2023 · Peer Review
  28. Artificial Skin Models for Animal-Free Testing: 3D Skin Reconstruct Approach, a Journey in the Past Two Decades
    Ruchi Pandey, Shiv Poojan · 2023 · Springer eBooks
  29. Laser-printed 3D full-thickness skin equivalent morphology and metabolism monitoring by dual-mode OCT/Fluorescence system
    Sergei G. Sokolovski, Arooj Khalid, Дрёмин Виктор Владимирович, Ayman El-Tamer, Maria Surmina, Celine Lancelot, Рафаилов Эдик Урихаевич · 2023 · Research Square
  30. Biotechnology in dermatology: present and future
    Anna V. Vlasova, Andrey A. Martynov, Maria A. Martynova · 2024 · Vestnik dermatologii i venerologii
  31. Novel Approaches to 3D Skin Cancer Models Usability in Research
    Iryna Levkovych, Anna Sobiepanek · 2024 · Interdisciplinary cancer research
  32. Development of human skin equivalents with inducible ceramide depletion for in vitro modelling of lipid deficiency
    Durotimi O Dina, Miriam Maiellaro, Emanuela Camera, John T. Connelly · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  33. Establishment of immortalized human minor salivary gland cells and chemokine expression induced by IFN-γ, TNF-α, and IL-1β
    Takako Naruse, Kouji Ohta, Misaki Akagi, Miyuki Sakuma, Yoko Ishida, Chieko Niwata, Takayuki Nakagawa, Shigehiro Ono, Fumie Shiba, Toshinori Ando et al. · 2025 · Odontology
  34. Enhanced differentiation potential of pigmented human epidermal equivalents
    Yunlong Y. Jia, Julia Bajsert, Arinnae I. Kurdian, Jessica Shiu, Miguel Pérez‐Aso, Scott X. Atwood · 2026 · Scientific Reports
  35. Mixing vs. layering: How to make an in vivo like skin model
    Anna V. Kardosh, Daria P. Revokatova, Polina Bikmulina, Yuri M. Efremov, Alexey L. Fayzullin, Nastasia V. Kosheleva, Svetlana Kotova, Andrey А. Svistunov, Anastasia I. Shpichka, Peter S. Timashev · 2025 · Biomaterials Advances
  36. Advanced 3D spheroid-based skin models and deep-learning based image analysis enable in-depth investigation of keratinocyte differentiation and barrier function
    Tiziana Cesetti, Claudia Buerger, Nathalie Couturier, Elina Nürnberg, Roman Bruch, Victoria Lang, Mathias Hafner, Markus Reischl, Torsten Fauth, Rüdiger Rudolf · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  37. From single cells to organotypic cultures: Measuring and analyzing keratinocyte migration
    Mayuri Vaish, Benjamin A. Nanes · 2026 · Journal of Investigative Dermatology
  38. Les allergies cutanées aux fragrances : mécanisme d'action et rôle du facteur de transcription Nrf2. Du modèle 2D au modèle 3D.
    Chloé Raffalli · 2018 · theses.fr (ABES)
  39. Evaluation in vitro de la sensibilisation cutanée aux xénobiotiques : Pertinence d’un modèle de co-culture épiderme reconstruit humain/cellules THP-1
    A. Thélu · 2019 · theses.fr (ABES)
  40. Development of a novel tunable hydrogel to support tissue formation in the context of full-thickness skin equivalents
    Mariana Carrancá · 2020
  41. Open-air human skin equivalent platform enabling photobiological studies and topical product testing
    Suzuha Asano, Yuya Morimoto · 2026 · Biofabrication
  42. Nanocosmetics: Regulatory Frameworks and Safety Assessment from a One Health Perspective
    Patrícia Mazureki Campos, Fabíola Silva Garcia Praça, Bruna Horne Larocca, Brenda Alves Lopes, Marcela Novak Gumy, Wanessa Silva Garcia Medina, Patrícia Mathias Döll‐Boscardin · 2026 · Brazilian Archives of Biology and Technology
  43. Method and Analysis of High-Calcium Induced Differentiation of Human Primary Keratinocytes In Vitro
    Sarmistha Mahanty, Dharna Saini · 2026 · Methods and Protocols
  44. Combining advanced 3D spheroid-based skin models with deep-learning-based image analysis enables in-depth investigation of keratinocyte differentiation and barrier function
    Tiziana Cesetti, Claudia Buerger, Nathalie Couturier, Elina Nürnberg, Roman Bruch, Mario Vitacolonna, Victoria Lang, Mathias Hafner, Markus Reischl, Torsten Fauth et al. · 2026 · Frontiers in Bioengineering and Biotechnology
  45. IFN-κ directs antiviral immunity in human skin
    Jafira M. Johnson, Laurellee Payne, Pooja Parameswaran, Yongzhi Chen, Mrinal K. Sarkar, Anthony M. Coon, Joanne Michelle Kahlenberg, Johann Eli Gudjonsson, Katherine A. Fitzgerald, Mehdi Rashighi et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  46. Immortalized keratinocyte cell lines for tissue engineered 3D skin and epidermal modeling: prospects, challenges, and limitations
    Jaimy A Klijnhout, Stefania Paola Bruno, Núria Pell, Alessandro Paolini, Craig Murdoch, Sandrine Dubrac, James G. Rheinwald, Ellen H. J. van den Bogaard, Nsrein Ali, Andrea Masotti et al. · 2026 · Journal of Investigative Dermatology
  47. Biofabrication of Gingival and Alveolar Bone Equivalents: Current Strategies, Advances and Future Directions
    Mira Hammad, Iason Chatzimentor, Vasiliki Stefanidou, Petros T Koidis, Danae Anastasia Apatzidou, Pierre Layrolle · 2026 · Current Oral Health Reports