What Is Gender Dysphoria? A Critical Systematic Narrative Review
Open accessAbstract
In the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders, the American Psychiatric Association has changed the diagnosis of gender identity disorder to gender dysphoria (GD). In this critical narrative review we ask: What is gender dysphoria? We report on some of the inconsistencies in the articles that foreground distress while obfuscating the fact that not all trans and intersex people suffer stress or impaired functioning, and the inappropriate referencing to intersex people in the diagnostic criterion, claims about the GD diagnosis contributing to the depathologization of and reducing stigma surrounding trans people, the conceptualizations of “gender dysphoric” research subjects, and finally we question the etiological approaches using GD as a conceptual framework. We further suggest that there are a number of methodological issues that need to be resolved to be able to claim that the GD diagnosis can be validated. To shed light on these paradoxes and methodological issues in the DSM-5, we report on the content validity of GD by reviewing research articles postdiagnostic inception. These findings will contribute to the debate about the validity of GD as a diagnosis for the 21st century for those people who need to live a different gender to that assigned at birth.
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The dissonance between a person's gender and the gender assigned to them at birth can lead to negative effects, including distress, depression, and gender dysphoria, that can be alleviated through transitioning.
“The dissonance between a person's gender and the gender assigned to them at birth can lead to negative effects, including distress, depression, and gender dysphoria [21], that can be alleviated through transitioning.”
From Paradoxes of Openness: Trans Experiences in Open Source Software (2024) · cites this paper as [21]
In “Foregrounding ‘distress’” (page not provided), the review says incongruence can result in gender dysphoria and distress for a subset of transgender people. It does not identify depression as an effect of that incongruence. The review also cautions in “Not all trans and intersex people suffer from GD” (page not provided) that distress should not be presumed for everyone. (LLM, conf=0.86)
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Research works printed but not linked: 50
- [1]Davy Z, Sørlie A, Suess Schwend A Democratising diagnoses? The role of the depathologisation perspective in constructing corporeal trans citizenship. Crit Soc Policy 2017; 38: 13– 34
- [2]Drescher J Controversies in gender diagnoses. LGBT Health 2013; 1: 10– 14 26789504
- [7]Zucker KJ, Cohen-Kettenis PT, Drescher J, et al. Memo outlining evidence for change for gender identity disorder in the DSM-5. Arch Sex Behav 2013; 42: 901– 914 23868018
- [8]Schneider C, Cerwenka S, Nieder TO, et al. Measuring gender dysphoria: a multicenter examination and comparison of the Utrecht gender dysphoria scale and the gender identity/gender dysphoria questionnaire for adolescents and adults. Arch Sex Behav 2016; 45: 551– 558 26883025
- [10]Hird MJ A typical gender identity conference? Some disturbing reports from the therapeutic front lines. Fem Psychol 2003; 13: 181– 199
- [11]Miller SI, Fredericks M, Perino FJ Social science research and policymaking: Meta-analysis and paradox. Protosociology 2008; 25: 186– 205
- [12]Fisk NM Gender dysphoria syndrome—the conceptualization that liberalizes indications for total gender reorientation and implies a broadly based multi-dimensional rehabilitative regimen. West J Med 1974; 120: 386– 391 4839483 PMC1130142
- [13]Kutchins H, Kirk SA Making Us Crazy: DSM: The Psychiatric Bible and the Creation of Mental Disorders. New York: The Free Press, 1997
- [14]Davy Z The DSM-5 and the politics of diagnosing transpeople. Arch Sex Behav 2015; 44: 1165– 1176 26054486
- [15]Kutchins H, Kirk SA DSM-III-R: The conflict over new psychiatric diagnoses. Health Soc Work 1989; 14: 91– 101 2714710
- [16]Szasz TS Antipsychiatry: Quakery Squared. Syracuse NY: Syracuse University Press, 2009
- [17]Szasz TS The Manufacture of Madness: A Comparative Study of the Inquisition and the Mental Health Movement. Syracuse, NY: Syracuse University Press, 1997
- [18]Suess A, Espineira K, Walters PC Depathologization. Transgender Stud Q 2014; 1: 73– 77
- [21]Ansara YG, Hegarty P Cisgenderism in psychology: Pathologizing and misgendering children from 1999 to 2008. Psychol Sex 2012; 3: 137– 160
- [22]Silverstein C Wearing two hats: the pyschologist as activist and therapist. In: Activism and LGBT Psychology. (Glassgold JM, Drescher J; eds). New York: The Howarth Medical Press, 2007, pp. 9– 35
- [23]Suppe F Classifying sexual disorders: the diagnostic and statistical manual of the American Psychiatric Association. J Homosex 1984; 9: 9– 28 6491263
- [25]Hegarty P Toward an LGBT-informed paradigm for children who break gender norms: A comment on Drummond et al. (2008) and Rieger et al. (2008). Dev Psychol 2009; 45: 895– 900 19586166
- [26]Cohen-Kettenis PT, Pfäfflin F The DSM diagnostic criteria for gender identity disorder in adolescents and adults. Arch Sex Behav 2009; 39: 499– 513 19838784
- [27]Hill DB, Willoughby BLB The development and validation of the genderism and transphobia scale. Sex Roles 2005; 53: 531– 544
- [28]Lev AI Disordering gender identity: Gender identity disorder in the DSM-IV-TR. J Psychol Hum Sex 2006; 17: 35– 69
- [29]Meyer-Bahlburg HFL Male gender identity in an XX individual with congenital adrenal hyperplasia. J Sex Med 2009; 6: 297– 298 18761588
- [31]Zucker KJ The DSM diagnostic criteria for gender identity disorder in children. Arch Sex Behav 2010; 39: 477– 498 19842027
- [32]Zucker KJ The science and politics of DSM-5. In: Classifying Sex: Debating DSM-5. University of Cambridge, 2013
- [33]Lev AI Gender dysphoria: Two steps forward, one step back. Clin Soc Work J 2013; 41: 288– 296
- [34]Cohen-Kettenis PT, van Goozen SH Sex reassignment of adolescent transsexuals: a follow-up study. J Am Acad Child Adolesc Psychiatry 1997; 36: 263– 271 9031580
- [35]Smith YLS, Van Goozen SHM, Kuiper AJ, et al. Sex reassignment: Outcomes and predictors of treatment for adolescent and adult transsexuals. Psychol Med 2005; 35: 89– 99 15842032
- [36]Deogracias JJ, Johnson LL, Meyer-Bahlburg HFL, et al. The gender identity/gender dysphoria questionnaire for adolescents and adults. J Sex Res 2007; 44: 370– 379 18321016
- [37]Zucker KJ Reports from the DSM-V work group on sexual and gender identity disorders. Arch Sex Behav 2010; 39: 217– 220 19760144
- [38]Whittemore R, Chase SK, Mandle CL Validity in qualitative research. Qual Health Res 2001; 11: 522– 537 11521609
- [39]Hammersley M Some notes on the terms ‘validity’ and ‘reliability’. Br Educ Res J 1987; 13: 73– 82
- [40]Pyett PM Validation of qualitative research in the “real world.” Qual Health Res 2003; 13: 1170– 1179 14556426
- [41]Anastasi A, Urbina S Psychological Testing, 7th ed. Upper Saddle River: Prentice Hall, 1997
- [42]Gough D, Thomas J, Oliver S Clarifying differences between review designs and methods. Syst Rev 2012; 1: 1– 9 22681772 PMC3533815
- [43]Campbell MM, Artz L, Stein DJ Sexual disorders in DSM-5 and ICD-11: A conceptual framework. Curr Opin Psychiatry 2015; 28: 435– 439 26382166
- [44]Barry KM, Farrell B, Levi JL, et al. A bare desire to harm: transgender people and the equal protection clause. Boston Coll Law Rev 2016; 57: 507– 582
- [45]Bouman WP, Richards C Diagnostic and treatment issues for people with gender dysphoria in the United Kingdom. Sex Relationship Ther 2013; 28: 165– 171
- [46]Bachmann GA, Mussman B The aging population: imperative to uncouple sex and gender to establish “gender equal” health care. Maturitas 2015; 80: 421– 425 25771042
- [47]Atkinson SR, Russell D Gender dysphoria. Aust Fam Physician 2015; 44: 792– 796 26590617
- [49]Frank AW From sick role to narrative subject: an analytic memoir. Health 2016; 20: 9– 21 26582351
- [50]Zucker KJ, Lawrence AA, Kreukels BPC Gender dysphoria in adults. Annu Rev Clin Psychol 2016; 12: 217– 247 26788901
- [51]Arcelus J, Bouman WP, Van Den Noortgate W, et al. Systematic review and meta-analysis of prevalence studies in transsexualism. Eur Psychiatry 2015; 30: 807– 815 26021270
- [53]de Vries ALC, McGuire JK, Steensma TD, et al. Young adult psychological outcome after puberty suppression and gender reassignment. Pediatrics 2014; 134: 696– 704 25201798
- [54]Gijs L, Brewaeys A Surgical treatment of gender dysphoria in adults and adolescents: recent developments, effectiveness, and challenges. Annu Rev Sex Res 2007; 18: 178– 224
- [55]Allison R Aligning bodies with minds: the case for medical and surgical treatment of gender dysphoria. J Gay Lesbian Ment Health 2010; 14: 139– 144
- [56]Ahmad S, Barrett J, Beaini AY, et al. Gender dysphoria services: A guide for general practitioners and other healthcare staff. Sex Relationship Ther 2013; 28: 172– 185
- [57]Thyen U, Richter-Appelt H, Wiesemann C, et al. Deciding on gender in children with intersex conditions. Treatments Endocrinol 2005; 4: 1– 8 15649096
- [58]Benjamin H The Transsexual Phenomenon. New York: Julian Press, 1966 5233741
- [59]Bockting WO Vulnerability and resilience among gender-nonconforming children and adolescents: mental health professionals have a key role to play. J Am Acad Child Adolesc Psychiatry 2016; 55: 441– 443 27238062
- [60]Tamar-Mattis A, Diamond M Managing variation in sex development. J Pediatr Endocrinol Metab 2007; 20: 552– 553 17550222
- [61]Diamond M, Beh HG Variations of sex development instead of disorders of sex development. Arch Dis Child 2006; 92: 8 9
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Paradoxes of Openness: Trans Experiences in Open Source Software
Frluckaj, H., Stevens, N., Howison, J., & Dabbish, L. (2024) · Proceedings of the ACM on Human-Computer Interaction · doi:10.1145/3687047 · Cited by 5 · see citing works
- Authors
- Davy, Z., & Toze, M.
- Affiliations
- De Montfort University (GB)
- University of Lincoln (GB)
- Corresponding author
- Davy, Zowie
- Venue
- Transgender Health
- Publisher
- SAGE Publications
- Published
- 2018-11
- Volume
- 3
- Issue
- 1
- Pages
- 159-169
- ISSN
- 2380-193X (ISSN-L)
- PMC
- PMC6225591
- OpenAlex
- W2900181751
- Cited by
- 154
- References
- 0
- Citations by year
- 2026: 9 · 2025: 24 · 2024: 28 · 2023: 23 · 2022: 29 · 2021: 15 · 2020: 21 · 2019: 5
- FWCI
- 1.51
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- Transgender Health (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, other-oa)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Lincoln Repository (University of Lincoln) (acceptedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- DMU Open Research Archive (De Montfort University) (submittedVersion)
- Figshare (submittedVersion, cc-by)
- Topics
- Social Sciences › Psychology › Social Psychology › LGBTQ Health, Identity, and Policy
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Sexual Differentiation and Disorders
- Social Sciences › Gender Studies › Gender Roles and Identity Studies
- Keywords
- gender dysphoria, DSM-5, transgender people, intersex people, diagnostic validity, content validity, distress, depathologization, stigma, etiology, research subjects
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