The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Retinoic acid induces transforming growth factor-beta 2 in cultured keratinocytes and mouse epidermis.
Open accessAbstract
We have studied the functional interaction between retinoic acid and transforming growth factor-beta (TGF-beta), using the mouse epidermis as a model system. Treatment with retinoic acid increases expression of TGF-beta 2 in cultured keratinocytes in vitro, as well as in the epidermis in vivo. This TGF-beta 2 is secreted in a biologically active form that can bind to surface receptors, in contrast to most other conditions in which TGF-beta is secreted in a latent form. Specific antibodies to TGF-beta 2 partially reverse the ability of retinoic acid to inhibit DNA synthesis in cultured keratinocytes. The regulation of TGF-beta 2 expression by retinoic acid may have important physiological and pharmacological roles in the maintenance of epidermal homeostasis.
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Cites
A human retinoic acid receptor which belongs to the family of nuclear receptors
Petkovich, M., Brand, N. J., Krust, A., & Chambon, P. (1987) · Nature · doi:10.1038/330444a0 · Cited by 2,214
Identification of a receptor for the morphogen retinoic acid
Giguere, V., Ong, E. S., Segui, P., & Evans, R. M. (1987) · Nature · doi:10.1038/330624a0 · Cited by 1,965
Cited by
Mechanisms of photoaging and chronological skin aging
Fisher, G. J., Kang, S., Varani, J., Bata-Csorgo, Z., Wan, Y., Datta, S., & Voorhees, J. J. (2002) · Archives of Dermatology · doi:10.1001/archderm.138.11.1462 · Cited by 1,849
Epidermal differentiation: the bare essentials.
Fuchs, E. (1990) · The Journal of cell biology · doi:10.1083/jcb.111.6.2807 · Cited by 658
Transforming growth factor-β in cancer and metastasis
Jakowlew, S. B. (2006) · Cancer and Metastasis Reviews · doi:10.1007/s10555-006-9006-2 · Cited by 517
Millan, F. A., Denhez, F., Kondaiah, P., & Akhurst, R. J. (1991) · Development · doi:10.1242/dev.111.1.131 · Cited by 498
Sato, Y., Tsuboi, R., Lyons, R., Moses, H., & Rifkin, D. B. (1990) · The Journal of cell biology · doi:10.1083/jcb.111.2.757 · Cited by 444
Metadata
- Authors
- Glick, A. B., Flanders, K. C., Danielpour, D., Yuspa, S. H., & Sporn, M. B.
- Venue
- Cell Regulation
- Published
- 1989-11
- Volume
- 1
- Issue
- 1
- Pages
- 87-97
- ISSN
- 1044-2030 (ISSN-L)
- OpenAlex
- W1984172347
- Cited by
- 330
- References
- 2
- FWCI
- 10.54
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Retinoic acid induces transforming growth factor-beta 2 in cultured keratinocytes and mouse epidermis. https://app.cochat.ai/papers/10.1091/mbc.1.1.87
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- Glick, A. B., Flanders, K. C., Danielpour, D., Yuspa, S. H., & Sporn, M. B. (1989). Retinoic acid induces transforming growth factor-beta 2 in cultured keratinocytes and mouse epidermis. Cell Regulation. https://doi.org/10.1091/mbc.1.1.87
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
