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Myofibroblast Development Is Characterized by Specific Cell-Cell Adherens Junctions
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Myofibroblasts of wound granulation tissue, in contrast to dermal fibroblasts, join stress fibers at sites of cadherin-type intercellular adherens junctions (AJs). However, the function of myofibroblast AJs, their molecular composition, and the mechanisms of their formation are largely unknown. We demonstrate that fibroblasts change cadherin expression from N-cadherin in early wounds to OB-cadherin in contractile wounds, populated with α-smooth muscle actin (α-SMA)-positive myofibroblasts. A similar shift occurs during myofibroblast differentiation in culture and seems to be responsible for the homotypic segregation of α-SMA-positive and -negative fibroblasts in suspension. AJs of plated myofibroblasts are reinforced by α-SMA–mediated contractile activity, resulting in high mechanical resistance as demonstrated by subjecting cell pairs to hydrodynamic forces in a flow chamber. A peptide that inhibits α-SMA–mediated contractile force causes the reorganization of large stripe-like AJs to belt-like contacts as shown for enhanced green fluorescent protein-α–catenin-transfected cells and is associated with a reduced mechanical resistance. Anti-OB-cadherin but not anti-N-cadherin peptides reduce the contraction of myofibroblast-populated collagen gels, suggesting that AJs are instrumental for myofibroblast contractile activity.
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“indeed, during the fibroblast-tomyofibroblast transition a decrease of N-cadherin expression and an increase of OB-cadherin/cadherin-11 have been described [21].”
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Cites
Epithelial–mesenchymal transitions in tumour progression
Thiery, J. P. (2002) · Nature reviews. Cancer · doi:10.1038/nrc822 · Cited by 6,767
Myofibroblasts and mechano-regulation of connective tissue remodelling
Tomasek, J. J., Gabbiani, G., Hinz, B., Chaponnier, C., & Brown, R. A. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm809 · Cited by 4,290
Self-citationDesmoulière, A., Geinoz, A., Gabbiani, F., & Gabbiani, G. (1993) · The Journal of Cell Biology · doi:10.1083/jcb.122.1.103 · Cited by 2,269
The third helix of the Antennapedia homeodomain translocates through biological membranes.
Derossi, D., Joliot, A., Chassaing, G., & Prochiantz, A. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)34080-2 · Cited by 2,034
Skalli, O., Ropraz, P., Trzeciak, A. M., Benzonana, G., Gillessen, D., & Gabbiani, G. (1986) · The Journal of Cell Biology · doi:10.1083/jcb.103.6.2787 · Cited by 1,622
Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction
Gabbiani, G., Ryan, G. B., & Majno, G. (1971) · Experientia · doi:10.1007/bf02147594 · Cited by 1,485
Alpha-Smooth Muscle Actin Expression Upregulates Fibroblast Contractile Activity
Hinz, B., Celetta, G., Tomasek, J. J., Gabbiani, G., & Chaponnier, C. (2001) · Molecular Biology of the Cell · doi:10.1091/mbc.12.9.2730 · Cited by 1,288
Self-citationDarby, I. A., Skalli, O., & Gabbiani, G. (1990) · PubMed · Cited by 1,180
Bhowmick, N., Ghiassi, M., Bakin, A. V., Aakre, M., Lundquist, C., Engel, M., Arteaga, C., & Moses, H. (2001) · Molecular Biology of the Cell · doi:10.1091/mbc.12.1.27 · Cited by 1,087
Role of tissue stroma in cancer cell invasion
De Wever, O., & Mareel, M. (2003) · The Journal of Pathology · doi:10.1002/path.1398 · Cited by 1,042
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Items 101–200 of 231
Intestinal Myofibroblast TRPC6 Channel May Contribute to Stenotic Fibrosis in Crohnʼs Disease
Kurahara, L. H., Sumiyoshi, M., Aoyagi, K., Hiraishi, K., Nakajima, K., Nakagawa, M., Hu, Y., & Inoue, R. (2015) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000295 · Cited by 40
Morphological and molecular pathology of CCL4‐induced hepatic fibrosis in connexin43‐deficient mice
Cogliati, B., da Silva, T. C., Aloia, T. P. A., Chaible, L. M., Real‐Lima, M. A., Sanches, D. S., Matsuzaki, P., Hernandez‐Blazquez, F. J., & Dagli, M. L. (2010) · Microscopy Research and Technique · doi:10.1002/jemt.20926 · Cited by 39
Novel approaches to target fibroblast mechanotransduction in fibroproliferative diseases
Ezzo, M., & Hinz, B. (2023) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2023.108528 · Cited by 39
Self-citationWang, H., Leinwand, L. A., & Anseth, K. S. (2014) · The FASEB Journal · doi:10.1096/fj.14-254623 · Cited by 36
Beyond the epithelium: Cadherin function in fibrous connective tissues
Sayegh, T. Y. E., Kapùs, A., & McCulloch, C. A. (2007) · FEBS Letters · doi:10.1016/j.febslet.2006.12.029 · Cited by 36
Rizzo, S., Basso, C., Lazzarini, E., Celeghin, R., Paolin, A., Gerosa, G., Valente, M., Thiene, G., & Pilichou, K. (2015) · Cardiovascular Pathology · doi:10.1016/j.carpath.2015.07.009 · Cited by 36
Effects of TGF-β2 on Cadherins and β-Catenin in Human Trabecular Meshwork Cells
Wecker, T., Han, H., Börner, J., Grehn, F. J., & Schlunck, G. (2013) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.13-12669 · Cited by 35
Guo, X., José, P. A., & Chen, S. (2011) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00204.2010 · Cited by 34
Cell-cell junctions in developing and adult tendons
Theodossiou, S. K., Murray, J. B., & Schiele, N. R. (2019) · Tissue Barriers · doi:10.1080/21688370.2019.1695491 · Cited by 33
Mitochondrial fission and bioenergetics mediate human lung fibroblast durotaxis
Guo, T., Jiang, C., Yang, S., Zhu, Y., He, C., Carter, A. B., Antony, V. B., Peng, H., & Zhou, Y. (2022) · JCI Insight · doi:10.1172/jci.insight.157348 · Cited by 35
Rickelt, S., Winter‐Simanowski, S., Noffz, E., Kuhn, C., & Franke, W. W. (2009) · International Journal of Cancer · doi:10.1002/ijc.24552 · Cited by 32
Barth, M., Schumacher, H., Kuhn, C., Akhyari, P., Lichtenberg, A., & Franke, W. W. (2009) · Cell and Tissue Research · doi:10.1007/s00441-009-0806-x · Cited by 31
Aoyagi, K., Maeno, T., Matsui, H., Ueno, M., Hara, K., Aoki, Y., Aoki, F., Shimizu, T., Doi, H., Kawai‐Kowase, K., et al. (2010) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2009-0140oc · Cited by 31
Chen, S., Shiau, A., Li, Y., Lin, C., Jou, I., Liu, M.-F., Wu, C., & Wang, C. (2014) · Arthritis & Rheumatology · doi:10.1002/art.38899 · Cited by 30
Tozzi, P. (2013) · Journal of Bodywork and Movement Therapies · doi:10.1016/j.jbmt.2013.11.010 · Cited by 34
Myofibroblasts in interstitial lung diseases show diverse electron microscopic and invasive features
Karvonen, H. M., Lehtonen, S. T., Sormunen, R. T., Harju, T. H., Lappi‐Blanco, E., Bloigu, R., & Kaarteenaho, R. L. (2012) · Laboratory Investigation · doi:10.1038/labinvest.2012.95 · Cited by 30
Characterization of Cell Subpopulations Expressing Progenitor Cell Markers in Porcine Cardiac Valves
Wang, H., Sridhar, B. V., Leinwand, L. A., & Anseth, K. S. (2013) · PLoS ONE · doi:10.1371/journal.pone.0069667 · Cited by 32
Sustained delivery of growth factors with high loading efficiency in a layer by layer assembly
Damanik, F., Brunelli, M., Pastorino, L., Ruggiero, C., van Blitterswijk, C., Rotmans, J. I., & Moroni, L. (2019) · Biomaterials Science · doi:10.1039/c9bm00979e · Cited by 30
Myofibroblast specific targeting approaches to improve fibrosis treatment
Beaven, E., Kumar, R., Bhatt, H. N., Esquivel, S. V., & Nurunnabi, M. (2022) · Chemical Communications · doi:10.1039/d2cc04825f · Cited by 30
Balic, A., Perver, D., Pagella, P., Rehrauer, H., Stadlinger, B., Moor, A. E., Viola Vogel, B., & Mitsiadis, T. A. (2023) · International Journal of Oral Science · doi:10.1038/s41368-023-00238-z · Cited by 32
Isometric Contraction of Dupuytren’s Myofibroblasts Is Inhibited by Blocking Intercellular Junctions
Verhoekx, J. S. N., Verjee, L. S., Izadi, D., Chan, J. K.-K., Nicolaidou, V., Davidson, D., Midwood, K. S., & Nanchahal, J. (2013) · Journal of Investigative Dermatology · doi:10.1038/jid.2013.219 · Cited by 29
Teo, Z. Q., Chan, J. S. K., Chong, H. C., Sng, M. K., Choo, C. C., Phua, G. Z. M., Teo, D. J. R., Zhu, P., Choong, C. S. N., Wong, M. T. C., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-05869-x · Cited by 30
Rickelt, S., Franke, W. W., Dörflinger, Y., Goerdt, S., Brandner, J. M., & Peitsch, W. K. (2008) · Cell and Tissue Research · doi:10.1007/s00441-008-0704-7 · Cited by 28
Transition of asthmatic bronchial fibroblasts to myofibroblasts is inhibited by cell–cell contacts
Michalik, M., Pierzchalska, M., Włodarczyk, A., Wójcik‐Pszczoła, K., Czyż, J., Sanak, M., & Madeja, Z. (2011) · Respiratory Medicine · doi:10.1016/j.rmed.2011.04.009 · Cited by 29
Iacopino, F., Angelucci, C., & Sica, G. (2012) · PubMed · Cited by 27
Bi, J., Intriago, B., Koivisto, L., Jiang, G., Häkkinen, L., & Larjava, H. (2020) · Journal Of Clinical Periodontology · doi:10.1111/jcpe.13293 · Cited by 30
Molecular and Cellular Basis of Hypertrophic Scarring
Kwan, P. O., Desmoulière, A., & Tredget, E. E. (2018) · Elsevier eBooks · doi:10.1016/b978-0-323-47661-4.00045-9 · Cited by 28
Hofmann, I., Kuhn, C., & Franke, W. W. (2008) · Cell and Tissue Research · doi:10.1007/s00441-008-0725-2 · Cited by 25
Ultrastructural Features of Lung Fibroblast Differentiation into Myofibroblasts
Kaarteenaho–Wiik, R., Pääkkö, P. K., & Sormunen, R. T. (2009) · Ultrastructural Pathology · doi:10.1080/01913120802608430 · Cited by 23
Targeting of cadherin-11 decreases skin fibrosis in the tight skin-1 mouse model
Pedroza, M., Welschhans, R. L., & Agarwal, S. K. (2017) · PLoS ONE · doi:10.1371/journal.pone.0187109 · Cited by 24
Menezes, G. C., Miron-Mendoza, M., Ho, C.-H., Jiang, H., & Grinnell, F. (2008) · Experimental Cell Research · doi:10.1016/j.yexcr.2008.07.018 · Cited by 23
Gravesen, E., Mace, M. L., Nordholm, A., Hofman-Bang, J., Hruska, K. A., Nielsen, C. H., Kjær, A., Ølgaard, K., & Lewin, E. (2018) · PLoS ONE · doi:10.1371/journal.pone.0190820 · Cited by 22
Autocrine IL-6 drives cell and extracellular matrix anisotropy in scar fibroblasts
Kenny, F. N., Marcotti, S., de Freitas, D. B., Drudi, E. M., Leech, V., Bell, R. E., Easton, J., Díaz-de-la-Loza, M.-D.-C., Fleck, R. A., Allison, L., et al. (2023) · Matrix Biology · doi:10.1016/j.matbio.2023.08.004 · Cited by 25
Enhanced Adhesion of Stromal Cells to Invasive Cancer Cells Regulated by Cadherin 11
McAndrews, K. M., Yi, J., McGrail, D. J., & Dawson, M. (2015) · ACS Chemical Biology · doi:10.1021/acschembio.5b00353 · Cited by 21
Cadherin-11 and cardiac fibrosis: A common target for a common pathology
Riley, L. A., & Merryman, W. D. (2020) · Cellular Signalling · doi:10.1016/j.cellsig.2020.109876 · Cited by 21
The myofibroblast in connective tissue repair and regeneration
Hinz, B. (2010) · Elsevier eBooks · doi:10.1533/9781845697792.39 · Cited by 20
Self-citationWu, Y., Huang, Y., Wang, H., Yao, C. J., Sun, J., & Chao, Y. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms19010090 · Cited by 20
Suresh, R., Syamala, D., Janardhanan, M., Savithri, V., Anand, P., & Jose, A. (2016) · Journal of Oral and Maxillofacial Pathology · doi:10.4103/0973-029x.185898 · Cited by 20
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Eyden, B. P. (2009) · European Urology · doi:10.1016/j.eururo.2009.03.060 · Cited by 18
Cell–Cell Junctional Proteins in Cardiovascular Mechanotransduction
Michaelson, J., & Huang, H. (2011) · Annals of Biomedical Engineering · doi:10.1007/s10439-011-0439-6 · Cited by 18
Dupuytren's disease: a localised and accessible human fibrotic disorder
Layton, T. B., Williams, L. M., & Nanchahal, J. (2022) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2022.12.001 · Cited by 17
PTGES is involved in myofibroblast differentiation via HIF ‐1α‐dependent glycolysis pathway
Lin, M., Lee, Y., Liao, J., Chou, C., & Yang, Y. (2024) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.70157 · Cited by 17
Gardiner, J. C., & Cukierman, E. (2022) · Advances in cancer research · doi:10.1016/bs.acr.2022.01.004 · Cited by 16
Park, J. R., Ahn, J. H., Jung, M. H., Koh, J., Park, Y., Hwang, S., Jeong, Y., Kwak, C. H., Lee, Y. S., Seo, H. G., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0148510 · Cited by 16
Calcified Aortic Valve Disease in Patients With Familial Hypercholesterolemia
Hu, H., Cheng, J., Lin, S., Wang, S., & Chen, X. (2020) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0000000000000890 · Cited by 16
Metzger, W., Grenner, N., Motsch, S. E., Strehlow, R., Pohlemann, T., & Oberringer, M. (2007) · Tissue Engineering · doi:10.1089/ten.2007.0015 · Cited by 16
Aomatsu, E., Chosa, N., Nishihira, S., SUGIYAMA, Y., Miura, H., & Ishisaki, A. (2013) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2013.1607 · Cited by 15
Johnson, C. L., Riley, L. A., Bersi, M. R., Linton, M. F., & Merryman, W. D. (2021) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00263.2021 · Cited by 13
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Wang, Z., Ouyang, H., Chen, X., Yu, J., Abdalla, B. A., Chen, B., & Nie, Q. (2018) · Frontiers in Genetics · doi:10.3389/fgene.2018.00414 · Cited by 15
Lai, W., Wang, Y., Huang, C., Xu, H., Zheng, X., Li, K., Wang, J., & Lou, Z. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.116671 · Cited by 14
Youssef, J., Chen, P., Shenoy, V. B., & Morgan, J. R. (2012) · The FASEB Journal · doi:10.1096/fj.11-199414 · Cited by 14
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Devarasou, S., Kang, M., & Shin, J. H. (2024) · APL Bioengineering · doi:10.1063/5.0199024 · Cited by 12
Babu, P. K. V., Mirastschijski, U., Belge, G., & Radmacher, M. (2021) · European Biophysics Journal · doi:10.1007/s00249-021-01536-2 · Cited by 13
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Zhang, D., Feng, F., Liu, R., Zhu, W., & Yao, L. (2018) · Chinese Chemical Letters · doi:10.1016/j.cclet.2018.06.011 · Cited by 13
Cristià, E., Afzal‐Ahmed, I., Pérez‐Bosque, A., Amat, C., Naftalin, R. J., & Moretó, M. (2005) · The Journal of Membrane Biology · doi:10.1007/s00232-005-0773-4 · Cited by 13
Arena, S., Fazzari, C., Implatini, A., Torre, S., Villari, D., Arena, F., & Benedetto, V. D. (2009) · The Journal of Urology · doi:10.1016/j.juro.2009.02.059 · Cited by 12
Hata, J., Tanji, R., Onagi, A., Honda‐Takinami, R., Matsuoka, K., Hoshi, S., Sato, Y., Akaihata, H., Haga, N., & Kojima, Y. (2020) · International Journal of Urology · doi:10.1111/iju.14265 · Cited by 11
Cdh11: Roles in different diseases and potential value in disease diagnosis and treatment
Zhang, G., Wang, X., & Zhang, Q. (2023) · Biochemistry and Biophysics Reports · doi:10.1016/j.bbrep.2023.101576 · Cited by 10
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Hinz, B., Darby, I. A., Gabbiani, G., & Desmoulière, A. (2011) · Springer eBooks · doi:10.1007/978-94-007-0659-0_3 · Cited by 10
Self-citationLnc-ing NOTCH1 to Idiopathic Calcific Aortic Valve Disease
Merryman, W. D., & Clark, C. R. (2016) · Circulation · doi:10.1161/circulationaha.116.025601 · Cited by 10
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Ippolito, A., & Deshpande, V. S. (2022) · Biophysical Journal · doi:10.1016/j.bpj.2022.08.030 · Cited by 9
Clark, R. A. F. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-398358-9.00076-8 · Cited by 9
Proximate larval epidermal cell layer generates forces for Pupal thorax closure in Drosophila
Athilingam, T., Parihar, S. S., Bhattacharya, R., Rizvi, M. S., Kumar, A., & Sinha, P. (2022) · Genetics · doi:10.1093/genetics/iyac030 · Cited by 9
Kurahara, L. H., Hiraishi, K., Sumiyoshi, M., Doi, M., Hu, Y., Aoyagi, K., Jian, Y., & Inoue, R. (2016) · Journal of Smooth Muscle Research · doi:10.1540/jsmr.52.78 · Cited by 9
Li, J., Li, L., Yu, Y., Qin, R., Chen, Y., Chen, C., Dong, Y., Tan, Y., Liu, Y., & Liu, X. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1526828 · Cited by 8
Molecular and cellular basis of hypertrophic scarring
Kwan, P. O., Desmoulière, A., & Tredget, E. E. (2012) · Elsevier eBooks · doi:10.1016/b978-1-4377-2786-9.00045-x · Cited by 8
Generation of Cell-Instructive Collagen Gels through Thermodynamic Control
Liang, Y., Kong, H., & Tong, Y. W. (2013) · ACS Macro Letters · doi:10.1021/mz400512j · Cited by 8
Ultrastructural and functional characterization of myofibroblasts in lung diseases
Karvonen, H. M. (2014) · Cited by 7
Cadherin-11 integrates Piezo1 and interleukin-6 signaling to promote fibroblast activation
Astrab, L. R., & Caliari, S. R. (2026) · Biomaterials Science · doi:10.1039/d5bm01456e · Cited by 7
Piao, C., Zhuang, C., Ko, M. K., Hwang, D. W., & Lee, M. (2022) · Journal of drug targeting · doi:10.1080/1061186x.2022.2069781 · Cited by 7
BÜLOW, C. V., Oliveira‐Ferrer, L., Löning, T., Trillsch, F., Mahner, S., & Milde‐Langosch, K. (2015) · Molecular and Clinical Oncology · doi:10.3892/mco.2015.593 · Cited by 7
Yamamoto, A., Saito, T., Hosoya, T., Kawahata, K., Asano, Y., Sato, S., Mizoguchi, F., Yasuda, S., & Kohsaka, H. (2021) · Arthritis & Rheumatology · doi:10.1002/art.42042 · Cited by 7
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Kuijpers, K. A. J., Heesakkers, J. P. F. A., Hafmans, T. G. M., & Schalken, J. A. (2014) · BioMed Research International · doi:10.1155/2014/464217 · Cited by 7
OB‐cadherin cloning and expression in a model of wound repair in horses
Miragliotta, V., Lefebvre-Lavoie, J., Lussier, J. G., & Theoret, C. L. (2008) · Equine Veterinary Journal · doi:10.2746/042516408x322148 · Cited by 7
de la Torre, P., Pérez-Lorenzo, M. J., Alcazar-Garrido, A., Collado, J., Martínez-López, M., Acebal, L. F., Masero-Casasola, A. R., García, A., Gutiérrez-Vélez, M. C., Medina‐Polo, J., et al. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.1033080 · Cited by 7
White, M. J. V., Ozkan, M., Medellin, J. E. G., Raczy, M. M., Koss, K. M., Solanki, A., Zhang, Z. J., Alpar, A. T., Naved, B. A., Wertheim, J. A., et al. (2024) · Scientific Reports · doi:10.1038/s41598-024-70737-4 · Cited by 11
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Aljghami, M. E., Jeschke, M. G., & Amini‐Nik, S. (2019) · Journal of Anatomy · doi:10.1111/joa.12941 · Cited by 7
Tajima, H. (2009) · Oral Medicine & Pathology · doi:10.3353/omp.13.91 · Cited by 6
Transient expression of myofibroblast-like cells in rat rib fracture callus
McDonald, S. J., Dooley, P. C., McDonald, A. C., Schuijers, J. A., Ward, A. R., & Grills, B. L. (2012) · Acta Orthopaedica · doi:10.3109/17453674.2011.652891 · Cited by 6
Ghosh, K., & Clark, R. A. F. (2007) · Elsevier eBooks · doi:10.1016/b978-012370615-7/50080-9 · Cited by 6
Cadherin-11 targeted cell-specific liposomes enabled skin fibrosis treatment by inducing apoptosis
Bhatt, H. N., Diwan, R., Estevao, I. L., Dong, R., Smith, J., Xiao, C., Agarwal, S. K., & Nurunnabi, M. (2024) · Journal of Controlled Release · doi:10.1016/j.jconrel.2024.04.029 · Cited by 5
Greco, C. T., Akins, R. E., Epps, T. H. I., & Sullivan, M. O. (2017) · Advanced Biosystems · doi:10.1002/adbi.201700099 · Cited by 5
Selby, J. C. (2011) · Springer eBooks · doi:10.1007/978-1-4419-8083-0_9 · Cited by 5
White, M. J. V., Ozkan, M., Medellin, J. E. G., Solanki, A., & Hubbell, J. A. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.06.07.447403 · Cited by 5
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Shyer, J. A., Wehbe, F., Davidson, C. D., Bender, H. S., Thai, M., Cox, C., Missarova, A., Arlantico, A., Hall, B. M., Zhang, R., et al. (2026) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2536550123 · Cited by 4
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McCulloch, C. A., & Coelho, N. M. (2015) · Springer eBooks · doi:10.1007/978-3-319-17437-2_14 · Cited by 4
Takahashi, N. K., Chosa, N., Hasegawa, T., Nishihira, S., Okubo, N., Takahashi, M., Sugiyama, Y., Tanaka, M., & Ishisaki, A. (2011) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2011.07.013 · Cited by 4
Characterization of primary human leptomeningeal cells in 2D culture
Abubaker, M., Greaney, A. J., Newport, D. T., & Mulvihill, J. J. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e26744 · Cited by 4
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Mechanical and Matrix Regulation of Valvular Fibrosis
Blaser, M. C., & Simmons, C. A. (2015) · Springer eBooks · doi:10.1007/978-3-319-17437-2_3 · Cited by 3
Plakoglobin expression in fibroblasts and its role in idiopathic pulmonary fibrosis
Matthes, S. A., LaRouere, T. J., Horowitz, J. C., & White, E. S. (2015) · BMC Pulmonary Medicine · doi:10.1186/s12890-015-0137-5 · Cited by 3
Pontes‐Júnior, J., Nunes, R. L. V., Reis, S. T., Oliveira, L. C. N. D., Viana, N. I., Leite, K. R. M., Bruschini, H., & Srougi, M. (2013) · BMC Urology · doi:10.1186/1471-2490-13-50 · Cited by 3
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Metadata
- Authors
- Hinz, B., Pittet, P., Smith-Clerc, J., Chaponnier, C., & Meister, J.-J.
- Affiliations
- École Polytechnique Fédérale de Lausanne (CH)
- University of Geneva (CH)
- Venue
- Molecular Biology of the Cell
- Published
- 2004-09
- Volume
- 15
- Issue
- 9
- Pages
- 4310-4320
- ISSN
- 1059-1524 (ISSN-L)
- 1939-4586
- PMC
- PMC515361
- OpenAlex
- W2096945892
- Cited by
- 231
- References
- 80
- Citations by year
- 2026: 9 · 2025: 10 · 2024: 10 · 2023: 7 · 2022: 11 · 2021: 15 · 2020: 13 · 2019: 7 · 2018: 14 · 2017: 8 · 2016: 8 · 2015: 16 · 2014: 18 · 2013: 12 · 2012: 16
- FWCI
- 2.04
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Molecular Biology of the Cell (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Infoscience (Ecole Polytechnique Fédérale de Lausanne) (submittedVersion)
- Infoscience (Ecole Polytechnique Fédérale de Lausanne) (submittedVersion, cc-by-nc-nd)
- Archive ouverte UNIGE (University of Geneva) (submittedVersion)
- Archive ouverte UNIGE (University of Geneva) (submittedVersion, cc-by)
- Funders
- National Science Foundation
- Biogen
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (102150, 3100A0)
- Université de Genève
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular Mechanics and Interactions
- Health Sciences › Medicine › Surgery › Wound Healing and Treatments
- Health Sciences › Medicine › Immunology and Allergy › Cell Adhesion Molecules Research
- Keywords
- myofibroblast differentiation, adherens junctions, N-cadherin, alpha-smooth muscle actin, cell contractility, alpha-catenin, stress fibers, mechanical resistance, collagen gel contraction, fibroblast differentiation
- MeSH terms
- Actins, Animals, Biomechanical Phenomena, Cell Differentiation, Cells, Cultured, Collagen, Female, Fibroblasts, Gels, Models, Biological, Skin, Wound Healing, Cadherins, Rats, Wistar, Adherens Junctions, Myoblasts, Rats
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