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ADVERSE REACTIONS TO PRESCRIBED DRUGS IN THE ELDERLY: A MULTICENTRE INVESTIGATION
Abstract
Of 1998 patients consecutively admitted to Geriatric Medicine Departments in England, Wales and Scotland in 1975--6, 81.3% were receiving prescribed drugs at time of admission. Adverse reactions were noted in 248 patients, representing 15.3% of prescribed drug takers. In 209 of these patients, it was thought that an adverse reaction had contributed to the need for admission to hospital. Full recovery from adverse reactions and sequelae occurred in 68% of those with such reactions. Hypotensive drugs, antiparkinsonian drugs and psychotropics carried the greatest risk of adverse reactions although the largest single number of adverse reactions (60) were due to diuretics which were by far the most commonly prescribed drugs (37.4% of sample).
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Citations
Cited by
Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients
Pirmohamed, M., James, S., Meakin, S., Green, C., Scott, A. K., Walley, T. J., Farrar, K., Park, B. K., & Breckenridge, A. M. (2004) · BMJ · doi:10.1136/bmj.329.7456.15 · Cited by 3,230
Bormate, A. B., Leboit, P. E., & McCalmont, T. H. (2008) · Archives of Dermatology · doi:10.1001/archderm.144.8.1020 · Cited by 731
Adverse drug reactions in elderly patients
Routledge, P. A., O'Mahony, M. S., & Woodhouse, K. W. (2004) · British Journal of Clinical Pharmacology · doi:10.1046/j.1365-2125.2003.01875.x · Cited by 476
Adverse drug events as a cause of hospital admission in the elderly
Chan, M., Nicklason, F., & Vial, J. H. (2001) · Internal Medicine Journal · doi:10.1046/j.1445-5994.2001.00044.x · Cited by 408
Management of drug therapy in the elderly
Desforges, J. F., Montamat, S. C., Cusack, B. J., & Vestal, R. E. (1989) · New England Journal of Medicine · doi:10.1056/nejm198908033210507 · Cited by 388
Metadata
- Authors
- WILLIAMSON, J., & CHOPIN, J. M.
- Venue
- Age and Ageing
- Publisher
- Oxford University Press (OUP)
- Published
- 1980
- Volume
- 9
- Issue
- 2
- Pages
- 73-80
- ISSN
- 0002-0729 (ISSN-L)
- 1468-2834
- OpenAlex
- W2143648744
- Cited by
- 418
- References
- 0
- FWCI
- 37.56
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: ADVERSE REACTIONS TO PRESCRIBED DRUGS IN THE ELDERLY: A MULTICENTRE INVESTIGATION. https://app.cochat.ai/papers/10.1093/ageing/9.2.73
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- WILLIAMSON, J., & CHOPIN, J. M. (1980). ADVERSE REACTIONS TO PRESCRIBED DRUGS IN THE ELDERLY: A MULTICENTRE INVESTIGATION. Age and Ageing. https://doi.org/10.1093/ageing/9.2.73
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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