Cited by 506Chronic Disease Management StrategiesClinical practice guidelines implementationPharmaceutical Practices and Patient Outcomes

Guidelines for People Not for Diseases: The Challenges of Applying UK Clinical Guidelines to People with Multimorbidity

Hughes, L. D., McMurdo, M. E. T., Guthrie, B.·2013·Age and Ageing

Abstract

Background currently one of the major challenges facing clinical guidelines is multimorbidity. Current guidelines are not designed to consider the cumulative impact of treatment recommendations on people with several conditions, nor to allow comparison of relative benefits or risks. This is despite the fact that multimorbidity is a common phenomenon. Objective to examine the extent to which National Institute of Health and Clinical Excellence (NICE) guidelines address patient comorbidity, patient centred care and patient compliance to treatment recommendations. Methods five NICE clinical guidelines were selected for review (type-2 diabetes mellitus, secondary prevention for people with myocardial infarction, osteoarthritis, chronic obstructive pulmonary disease and depression) as these conditions are common causes of comorbidity and the guidelines had all been produced since 2007. Two authors extracted information from each full guideline and noted the extent to which the guidelines accounted for patient comorbidity, patient centred care and patient compliance. The cumulative recommended treatment, follow-up and self-care regime for two hypothetical patients were then created to illustrate the potential cumulative impact of applying single disease recommendations to people with multimorbidity. Results comorbidity and patient adherence were inconsistently accounted for in the guidelines, ranging from extensive discussion to none at all. Patient centred care was discussed in ge…

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Registry

Crossref · 10.1093/ageing/afs100

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  • When multiple guidelines are used simultaneously, patients experience cumulative treatment burdens.

    “When multiple guidelines are used simultaneously, patients will experience cumulative treatment burdens.”
  • If clinicians were to adhere strictly to every NICE guideline for specific diseases, patients would face numerous appointments and be prescribed excessive medication.

    “If clinicians were to adhere strictly to every NICE guideline for specific diseases, patients would face numerous appointments and be prescribed excessive medication [155].”

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Authors
Hughes, L. D., McMurdo, M. E. T., & Guthrie, B.
Affiliations
University of Dundee (GB)
Corresponding author
Hughes, L. D.
Venue
Age and Ageing
Published
2012-08-21
Volume
42
Issue
1
Pages
62-69
ISSN
  • 0002-0729 (ISSN-L)
  • 1468-2834
OpenAlex
W2116189532
Cited by
506
References
4
Citations by year
2026: 16 · 2025: 29 · 2024: 43 · 2023: 34 · 2022: 40 · 2021: 36 · 2020: 42 · 2019: 41 · 2018: 35 · 2017: 42 · 2016: 42 · 2015: 43 · 2014: 39 · 2013: 20 · 2012: 2
FWCI
24.82
Type
journal article
Language
en
Open access
closed
Locations
  • Age and Ageing (publishedVersion)
  • PubMed (publishedVersion)
  • Discovery Research Portal (University of Dundee) (submittedVersion)
Topics
  • Health Sciences › Medicine › Epidemiology › Chronic Disease Management Strategies
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Clinical practice guidelines implementation
  • Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
Keywords
multimorbidity, clinical guidelines, NICE guidelines, comorbidities, patient-centered care, medication adherence, treatment burden, polypharmacy, type 2 diabetes, osteoarthritis, chronic obstructive pulmonary disease, depression, self-care
MeSH terms
Aged, Aged, 80 and over, Chronic Disease, United Kingdom, Humans, Patient Compliance, Self Care, Comorbidity, Practice Guidelines as Topic, Patient-Centered Care, Polypharmacy

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