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Ultra-processed food consumption is associated with increased risk of all-cause and cardiovascular mortality in the Moli-sani Study
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In the Moli-sani cohort, renal biomarkers explained 8-20% of associations with all-cause and cardiovascular mortality.
“In the Moli-sani cohort, renal biomarkers explained 8-20% of associations with all-cause and cardiovascular mortality.52”
From Ultra-processed foods and human health: the main thesis and the evidence (2025) · cites this paper as [52]
The Moli-sani study found that 20-33% of associations with all-cause and cardiovascular mortality were mediated by sugar intake, whereas saturated fats and sodium intake had minimal effects.
“The Moli-sani study found that 20-33% of associations with all-cause and cardiovascular mortality were mediated by sugar intake, whereas saturated fats and sodium intake had minimal effects.52”
From Ultra-processed foods and human health: the main thesis and the evidence (2025) · cites this paper as [52]
Cross-sectional analyses of cohort studies found a similar inverse relationship between the share of UPFs and protective foods.
“Cross-sectional analyses of cohort studies found a similar inverse relationship between the share of UPFs and these protective foods.[50][51][52]”
From Ultra-processed foods and human health: the main thesis and the evidence (2025) · cites this paper as [52]
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Cited by
Sorted by citations
Lichtenstein, A. H., Appel, L. J., Vadiveloo, M., Hu, F. B., Kris-Etherton, P. M., Rebholz, C. M., Sacks, F. M., Thorndike, A. N., Van Horn, L., Wylie-Rosett, J., et al. (2021) · Circulation · doi:10.1161/cir.0000000000001031 · Cited by 1,065
Martini, D., Godos, J., Bonaccio, M., Vitaglione, P., & Grosso, G. (2021) · Nutrients · doi:10.3390/nu13103390 · Cited by 481
Self-citationUltra-processed foods and human health: the main thesis and the evidence
Monteiro, C. A., Louzada, M. L., Steele-Martinez, E., Cannon, G., Andrade, G. C., Baker, P., Bes-Rastrollo, M., Bonaccio, M., Gearhardt, A. N., Khandpur, N., et al. (2025) · The Lancet · doi:10.1016/s0140-6736(25)01565-x · Cited by 339
Self-citationZhang, S., Gan, S., Zhang, Q., Liu, L., Meng, G., Yao, Z., Wu, H., Gu, Y., Wang, Y., Zhang, T., et al. (2022) · International Journal of Epidemiology · doi:10.1093/ije/dyab174 · Cited by 113
Metadata
- Authors
- Bonaccio, M., Di Castelnuovo, A., Costanzo, S., De Curtis, A., Persichillo, M., Sofi, F., Cerletti, C., Donati, M. B., de Gaetano, G., & Iacoviello, L.
- ORCID
- Bonaccio, Marialaura
- Venue
- The American Journal of Clinical Nutrition
- Publisher
- Elsevier BV
- Published
- 2021-02
- Volume
- 113
- Issue
- 2
- Pages
- 446-455
- ISSN
- 0002-9165
- Cited by
- 181
- References
- 5
- Language
- en
- Licence
- Funders
- Italian Ministry of Health (GR-2013-02356060)
- Italian Association for Cancer Research (12237)
- European Commission Seventh Framework Programme (HEALTH-F2-2011-278913)
- Pfizer Foundation
- Italian Ministry of University and Research (12237)
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