The Latex-Fixation Test: III. Agglutination Test for C-Reactive Protein and Comparison with the Capillary Precipitin Method

Singer, Jacques M.; Plotz, Charles M.; Pader, Elmer; Elster, Samuel K.

doi:10.1093/ajcp/28.6.611

Cited by 72Biomarkers in Disease MechanismsClinical Laboratory Practices and Quality ControlInflammation biomarkers and pathways

The Latex-Fixation Test: III. Agglutination Test for C-Reactive Protein and Comparison with the Capillary Precipitin Method

Singer, Jacques M., Plotz, Charles M., Pader, Elmer, Elster, Samuel K.·1957·American Journal of Clinical Pathology

DOI 10.1093/ajcp/28.6.611

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Abstract

Jacques M. Singer, M.D., Charles M. Plotz, M.D., Elmer Pader, M.D., Samuel K. Elster, M.D.; The Latex-Fixation Test: III. Agglutination Test for C-Reactive

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“The concentrations of CRP levels in healthy adults are normally less than 10 mg/L and serum levels of CRP may increase over 1000-fold following inflammation or infection [6,26,27].”
Background
Mycoplasma-Latex Agglutination Reaction
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A gel diffusion precipitin method for the estimation of C-reactive protein
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Development and Evaluation of a Simple Latex Agglutination Test for Diagnosis of Tuberculosis
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“Many early researchers were not able to detect “acute phase” protein in normal human sera using precipitation with CPS (2), capillary immunoprecipitation (18), complement fixation (19), latex agglutination (20) or agarose gel electrophoresis (21).”
Method
C-reactive protein in Gambian Africans with special reference to P. falciparum malaria
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RHEUMATISM AND ARTHRITIS:
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“[26] using Accurate C-reactive protein reagent test kit (Spectrum Diagnostics, Inc.”
Method
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“0e C-reactive protein (CRP) was quantified using the latex technique [18], and the quantification of cholesterol [19, 20], high-density lipoprotein (HDL) [21], LDL [22], triglycerides [23, 24], and glucose [25] was carried out using enzymatic methods according to the indications of BioSystems S.”
Method
Liposome turbidimetric assay (LTA)
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Immunoassay for serum C-reactive protein employing fluorophore-labelled reactants
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“Serum C-reactive protein level was determined by the latex agglutination method [17] [18].”
Method
Clinical observation on the origin of C-reactive protein in blood
Tetsuo, U. E. T. E., Ogi, K., Fukazawa, S., et al. (1971) · Clinical Biochemistry · doi:10.1016/s0009-9120(71)90141-x · Cited by 3 · see citing works
LVI The Tonsils and Rheumatic Fever
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“Quantitation of CRP was performed by immunoturbidimetric assay using AVITEX® CRP latex agglutination test kit (Omega Diagnostics Ltd, Scotland, UK) according to the method described by Singer et al. (1957).”
Method
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Method
Renal Enzymes and Microglobulins in Patients with Rheumathoid Arthritis
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Authors: Singer, J. M., Plotz, C. M., Pader, E., & Elster, S. K.
Affiliations: Mount Sinai Hospital (US)
Venue: American Journal of Clinical Pathology
Publisher: Oxford University Press (OUP)
Published: 1957-12-01
Volume: 28
Issue: 6
Pages: 611-617
ISSN: 0002-9173 (ISSN-L)
1943-7722
DOI: 10.1093/ajcp/28.6.611
OpenAlex: W2326068767
Cited by: 71
References: 0
Citations by year: 2026: 3 · 2023: 1 · 2022: 2 · 2021: 2 · 2020: 1 · 2019: 2 · 2018: 2 · 2017: 1 · 2016: 1 · 2014: 4 · 2013: 2
FWCI: 0.97
Type: journal article
Language: en
Open access: closed
Locations: American Journal of Clinical Pathology (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Immunology and Microbiology › Immunology › Biomarkers in Disease Mechanisms
Health Sciences › Medicine › Physiology › Clinical Laboratory Practices and Quality Control
Life Sciences › Immunology and Microbiology › Immunology › Inflammation biomarkers and pathways
Keywords: latex fixation test, C-reactive protein, agglutination test, serum protein quantification, latex agglutination test
MeSH terms: Agglutination Tests, Blood Proteins, C-Reactive Protein, Capillaries, Humans, Latex, Latex Fixation Tests, Precipitins

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The Latex-Fixation Test: III. Agglutination Test for C-Reactive Protein and Comparison with the Capillary Precipitin Method

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