CoChat
Sign Up
Cited by 110Air Quality and Health ImpactsOccupational and environmental lung diseasesCarcinogens and Genotoxicity Assessment

Exposure to Diesel and Gasoline Engine Emissions and the Risk of Lung Cancer

Parent, M.-E., Rousseau, M.-C., Boffetta, P., Cohen, A., Siemiatycki, J.·2006·American Journal of Epidemiology
DOI 10.1093/aje/kwj343
Open this paper in CoChat — free account

Abstract

Pollution from motor vehicles constitutes a major environmental health problem. The present paper describes associations between diesel and gasoline engine emissions and lung cancer, as evidenced in a 1979-1985 population-based case-control study in Montreal, Canada. Cases were 857 male lung cancer patients. Controls were 533 population controls and 1,349 patients with other cancer types. Subjects were interviewed to obtain a detailed lifetime job history and relevant data on potential confounders. Industrial hygienists translated each job description into indices of exposure to several agents, including engine emissions. There was no evidence of excess risks of lung cancer with exposure to gasoline exhaust. For diesel engine emissions, results differed by control group. When cancer controls were considered, there was no excess risk. When population controls were studied, the odds ratios, after adjustments for potential confounders, were 1.2 (95% confidence interval: 0.8, 1.8) for any exposure and 1.6 (95% confidence interval: 0.9, 2.8) for substantial exposure. Confidence intervals between risk estimates derived from the two control groups overlapped considerably. These results provide some limited support for the hypothesis of an excess lung cancer risk due to diesel exhaust but no support for an increase in risk due to gasoline exhaust.

Integrity signals

Registry

Crossref · 10.1093/aje/kwj343

Cites

66 of 66 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Using different controls in case-control studies has similar underlying principles to cross-context studies, but differences in exposure misclassification rather than confounding structures is the most common use.

    “Using different controls in case control studies22 has similar underlying principles to those described above for cross-context studies, but here differences in exposure misclassification (rather than confounding structures) is the most common use of this approach.22–24”

    From Triangulation in aetiological epidemiology (2017) · cites this paper as [24]

Cites

Flagged first, then by citations

4 of the 70 references couldn’t be matched to a known paper.

Cited by

Sorted by citations

Related

Authors
Parent, M.-E., Rousseau, M.-C., Boffetta, P., Cohen, A., & Siemiatycki, J.
Affiliations
  • Institut National de la Recherche Scientifique (CA)
  • Centre international de recherche sur le cancer (FR)
  • Health Effects Institute (US)
  • Université de Montréal (CA)
ORCID
Venue
American Journal of Epidemiology
Publisher
Oxford University Press (OUP)
Published
2006-10-13
Volume
165
Issue
1
Pages
53-62
ISSN
  • 0002-9262 (ISSN-L)
  • 1476-6256
DOI
10.1093/aje/kwj343
OpenAlex
W2106101493
Cited by
110
References
70
Citations by year
2026: 1 · 2025: 2 · 2024: 3 · 2022: 4 · 2021: 5 · 2020: 5 · 2019: 6 · 2018: 8 · 2017: 8 · 2016: 5 · 2015: 11 · 2014: 3 · 2013: 4 · 2012: 14
FWCI
3.81
Type
journal article
Language
en
Open access
closed
Locations
  • American Journal of Epidemiology (publishedVersion)
  • PubMed (publishedVersion)
  • Archivio istituzionale della ricerca (Alma Mater Studiorum Università di Bologna) (submittedVersion)
Funders
  • Health Effects Institute
  • Health Canada
Topics
  • Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Air Quality and Health Impacts
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Occupational and environmental lung diseases
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Carcinogens and Genotoxicity Assessment
Keywords
diesel exhaust, gasoline engine exhaust, lung cancer, occupational exposure, vehicle emissions, cancer risk
MeSH terms
Adult, Aged, Air Pollutants, Occupational, Vehicle Emissions, Gasoline, Health Surveys, Humans, Lung Neoplasms, Male, Middle Aged, Quebec, Surveys and Questionnaires, Risk Factors, Case-Control Studies, Occupational Exposure, Risk Assessment, Motor Vehicles

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review