Cited by 449Patient Safety and Medication ErrorsPharmaceutical Practices and Patient OutcomesPharmacovigilance and Adverse Drug Reactions

Comparison of methods for detecting medication errors in 36 hospitals and skilled-nursing facilities

Flynn, Elizabeth A., Barker, Kenneth N., Pepper, Ginette A., Bates, David W., Mikeal, Robert L.·2002·American Journal of Health-System Pharmacy

Abstract

The validity and cost-effectiveness of three methods for detecting medication errors were examined. A stratified random sample of 36 hospitals and skilled-nursing facilities in Colorado and Georgia was selected. Medication administration errors were detected by registered nurses (R.N.s), licensed practical nurses (L.P.N.s), and pharmacy technicians from these facilities using three methods: incident report review, chart review, and direct observation. Each dose evaluated was compared with the prescriber's order. Deviations were considered errors. Efficiency was measured by the time spent evaluating each dose. A pharmacist performed an independent determination of errors to assess the accuracy of each data collector. Clinical significance was judged by a panel of physicians. Observers detected 300 of 457 pharmacist-confirmed errors made on 2556 doses (11.7% error rate) compared with 17 errors detected by chart reviewers (0.7% error rate), and 1 error detected by incident report review (0.04% error rate). All errors detected involved the same 2556 doses. All chart reviewers and 7 of 10 observers achieved at least good comparability with the pharmacist's results. The mean cost of error detection per dose was $4.82 for direct observation and $0.63 for chart review. The technician was the least expensive observer at $2.87 per dose evaluated. R.N.s were the least expensive chart reviewers at $0.50 per dose. Of 457 errors, 35 (8%) were deemed potentially clinically significant; 71%…

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Crossref · 10.1093/ajhp/59.5.436

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  • A system redesign approach to changing physician behavior may be more effective and better accepted by physicians than traditional organizational efforts to improve quality using incentives.

    “A system redesign approach to changing physician behavior may not only be a more effective approach, but may be better accepted by physicians than traditional organizational efforts to improve quality using incentives.27”

    From Work system design for patient safety: the SEIPS model (2006) · cites this paper as [27]

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Authors
Flynn, E. A., Barker, K. N., Pepper, G. A., Bates, D. W., & Mikeal, R. L.
Affiliations
  • Auburn University (US)
  • School of Nursing, University of Colorado Health Sciences Center, Denver
  • Brigham and Women's Hospital (US)
  • DACE Company, West Monroe, LA
Corresponding author
Flynn, Elizabeth A.
Venue
American Journal of Health-System Pharmacy
Published
2002-03-01
Volume
59
Issue
5
Pages
436-446
ISSN
  • 1079-2082 (ISSN-L)
  • 1535-2900
OpenAlex
W2127264449
Cited by
449
References
0
Citations by year
2026: 2 · 2025: 2 · 2024: 11 · 2023: 8 · 2022: 12 · 2021: 11 · 2020: 11 · 2019: 18 · 2018: 18 · 2017: 25 · 2016: 17 · 2015: 23 · 2014: 31 · 2013: 30 · 2012: 26
FWCI
20.57
Type
journal article
Language
en
Open access
closed
Locations
  • American Journal of Health-System Pharmacy (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Health Professions › Emergency Medical Services › Patient Safety and Medication Errors
  • Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Pharmacovigilance and Adverse Drug Reactions
Keywords
medication errors, medication administration errors, direct observation, medical records review, cost-effectiveness, skilled nursing facilities, nurses, pharmacy technicians
MeSH terms
Colorado, Data Collection, Georgia, Humans, Medication Errors, Medication Systems, Hospital, Nursing Staff, Hospital, Pharmacy Technicians, Pharmacy Service, Hospital, Quality Control, Risk Management, Skilled Nursing Facilities, Chi-Square Distribution

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