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THE EFFECTS OF MODERATE ALCOHOL CONSUMPTION ON FEMALE HORMONE LEVELS AND REPRODUCTIVE FUNCTION
Abstract
Studies that have investigated the effect of moderate alcohol consumption on the level of oestrogens and progesterone in both pre- and post-menopausal women are reviewed. It is concluded that several lines of evidence point to an alcohol-induced rise in natural or synthetic oestrogen levels in women. Proposed mechanisms include an increased rate of aromatization of testosterone or a decreased rate of oxidation of oestradiol to oestrone. Moderate alcohol consumption has also been linked to decreased progesterone levels in pre-menopausal women. The relevance of these findings to female health, fertility and the timing of the menopause is considered.
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Citations
Cites
Alcohol and caffeine consumption and decreased fertility
Hakim, R. B., Gray, R. H., & Zacur, H. (1998) · Fertility and Sterility · doi:10.1016/s0015-0282(98)00257-x · Cited by 205
Cited by
Erol, A., & Karpyak, V. M. (2015) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2015.08.023 · Cited by 1,022
Homan, G. F., Davies, M., & Norman, R. (2007) · Human Reproduction Update · doi:10.1093/humupd/dml056 · Cited by 546
Smoke, alcohol and drug addiction and male fertility
Sansone, A., Di Dato, C., de Angelis, C., Menafra, D., Pozza, C., Pivonello, R., Isidori, A., & Gianfrilli, D. (2018) · Reproductive Biology and Endocrinology · doi:10.1186/s12958-018-0320-7 · Cited by 324
Low identification of alcohol use disorders in general practice in England
Cheeta, S., Drummond, C., Oyefeso, A., Phillips, T., Deluca, P., Perryman, K., & Coulton, S. (2008) · Addiction · doi:10.1111/j.1360-0443.2008.02198.x · Cited by 62
Mendelian randomisation approaches to the study of prenatal exposures: A systematic review
Diemer, E. W., Labrecque, J. A., Neumann, A., Tiemeier, H., & Swanson, S. A. (2021) · Paediatric and Perinatal Epidemiology · doi:10.1111/ppe.12691 · Cited by 21
Metadata
- Authors
- Gill, J.
- Venue
- Alcohol and Alcoholism
- Publisher
- Oxford University Press (OUP)
- Published
- 2000-09-01
- Volume
- 35
- Issue
- 5
- Pages
- 417-423
- ISSN
- 0735-0414 (ISSN-L)
- 1464-3502
- OpenAlex
- W2165386266
- Cited by
- 197
- References
- 1
- FWCI
- 1.66
- Type
- journal article
- Language
- en
- Open access
- closed
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- The paper
- Gill, J. (2000). THE EFFECTS OF MODERATE ALCOHOL CONSUMPTION ON FEMALE HORMONE LEVELS AND REPRODUCTIVE FUNCTION. Alcohol and Alcoholism. https://doi.org/10.1093/alcalc/35.5.417
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.