The DOI matches its Crossref record; 82 of the 82 references it cites were found in a registry or an index.
Causal Considerations on Alcohol and HIV/AIDS -- A Systematic Review
Abstract
AIM: The study aimed to explore the possible causal nature of the association between alcohol consumption and HIV/AIDS. METHODS: A review based on meta-analyses and reviews was conducted according to standard epidemiological criteria to distinguish causality from association, examining (i) the potential impact of alcohol on the incidence of HIV and (ii) alcohol's impact on worsening the disease course. RESULTS: In terms of incidence of HIV, although we found a consistent and strong association with consumption, there was not enough evidence for a causal connection. In particular, it is not clear whether personality traits such as sensation seeking or sexual compulsivity and psychiatric disorders such as antisocial personality disorder impact both alcohol consumption and risky sex, subsequently creating an association between both behaviors. In terms of worsening the disease course of HIV/AIDS, we found enough evidence for a causal impact of alcohol. Alcohol affects the immune system, thus contributing to a worsened course of HIV/AIDS. In addition, alcohol negatively impacts on behaviors that include support seeking and medication adherence. CONCLUSIONS: A randomized controlled clinical trial targeted toward at-risk HIV-negative individuals who live in areas with high HIV prevalence is suggested to test the effects of proven effective alcohol interventions on HIV incidence.
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Citations
Cites
The environment and disease: association or causation?
Hill, A. B. (2015) · Journal of the Royal Society of Medicine · doi:10.1177/0141076814562718 · Cited by 7,285
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Self-citationEzzati, M., López, A. D., Rodgers, A., & Murray, C. J. L. (2004) · Cited by 3,319
Adherence to Protease Inhibitor Therapy and Outcomes in Patients with HIV Infection
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Self-citationA System of Logic, Ratiocinative and Inductive
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Cited by
The relationship between different dimensions of alcohol use and the burden of disease—an update
Rehm, J., Gmel, G. E., Gmel, G., Hasan, O. S. M., Imtiaz, S., Popova, S., Probst, C., Roerecke, M., Room, R., Samokhvalov, A. V., et al. (2017) · Addiction · doi:10.1111/add.13757 · Cited by 1,204
Self-citationThe relation between different dimensions of alcohol consumption and burden of disease: an overview
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“While alcohol use is associated consistently with the prevalence and incidence of HIV [42–44], however, further research is needed to substantiate causality [45].”
Self-citationThe risks associated with alcohol use and alcoholism.
(2011) · PubMed Central · Cited by 556
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Self-citationWilliams, E. C., Hahn, J. A., Saitz, R., Bryant, K., Lira, M. C., & Samet, J. H. (2016) · Alcoholism: Clinical and Experimental Research · doi:10.1111/acer.13204 · Cited by 294
Metadata
- Authors
- Shuper, P. A., Neuman, M., Kanteres, F., Baliunas, D., Joharchi, N., & Rehm, J.
- Venue
- Alcohol and Alcoholism
- Publisher
- Oxford University Press (OUP)
- Published
- 2010-01-08
- Volume
- 45
- Issue
- 2
- Pages
- 159-166
- ISSN
- 0735-0414 (ISSN-L)
- 1464-3502
- OpenAlex
- W2000887305
- Cited by
- 306
- References
- 82
- FWCI
- 2.05
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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