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Homology modeling, model and software evaluation: three related resources.
Open accessAbstract
MOTIVATION: Homology modeling is rapidly becoming the method of choice for obtaining three-dimensional coordinates for proteins because genome projects produce sequences at a much higher rate than NMR and X-ray laboratories can solve the three-dimensional structures. The quality of protein models will not be immediately clear to novices and support with the evaluation seems to be needed. Expert users are sometimes interested in evaluating the quality of modeling programs rather than the quality of the models themselves. RESULTS: Three servers have been made available to the scientific community: a homology modeling server, a model quality evaluation server and a server that evaluates models built of proteins for which the structure is already known, thereby implicitly evaluating the quality of the modeling program. AVAILABILITY: The modeling-related servers and several structure analysis servers are freely available at http://swift.embl-heidelberg.de/servers/ CONTACT: gert.vriend@embl-heidelberg.de
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Cited by
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Metadata
- Authors
- Rodriguez, R., Chinea, G., Lopez, N., Pons, T., & Vriend, G.
- Venue
- Bioinformatics
- Publisher
- Oxford University Press (OUP)
- Published
- 1998-01-01
- Volume
- 14
- Issue
- 6
- Pages
- 523-528
- ISSN
- 1367-4803 (ISSN-L)
- 1367-4811
- OpenAlex
- W2148131811
- Cited by
- 345
- References
- 0
- FWCI
- 2.48
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Rodriguez, R., Chinea, G., Lopez, N., Pons, T., & Vriend, G. (1998). Homology modeling, model and software evaluation: three related resources. Bioinformatics. https://doi.org/10.1093/bioinformatics/14.6.523
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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.