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Cited by 527

The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.

An information-based sequence distance and its application to whole mitochondrial genome phylogeny

Open access
Li, Ming, Badger, Jonathan H., Chen, Xin, Kwong, Sam, Kearney, Paul, Zhang, Haoyong·2001·Bioinformatics

Abstract

Motivation: Traditional sequence distances require an alignment and therefore are not directly applicable to the problem of whole genome phylogeny where events such as rearrangements make full length alignments impossible. We present a sequence distance that works on unaligned sequences using the information theoretical concept of Kolmogorov complexity and a program to estimate this distance. Results: We establish the mathematical foundations of our distance and illustrate its use by constructing a phylogeny of the Eutherian orders using complete unaligned mitochondrial genomes. This phylogeny is consistent with the commonly accepted one for the Eutherians. A second, larger mammalian dataset is also analyzed, yielding a phylogeny generally consistent with the commonly accepted one for the mammals. Availability: The program to estimate our sequence distance, is available at http://www.cs.cityu.edu.hk/~cssamk/gencomp/GenCompress1.htm. The distance matrices used to generate our phylogenies are available at http://www.math.uwaterloo.ca/~mli/distance.html Contact: mli@wh.math.uwaterloo.ca * To whom correspondence should be addressed.

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Metadata

Authors
Li, M., Badger, J. H., Chen, X., Kwong, S., Kearney, P., & Zhang, H.
Venue
Bioinformatics
Published
2001-02-01
Volume
17
Issue
2
Pages
149-154
ISSN
  • 1367-4803 (ISSN-L)
  • 1367-4811
OpenAlex
W2125598538
Cited by
527
References
19
FWCI
7.60
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: An information-based sequence distance and its application to whole mitochondrial genome phylogeny. https://app.cochat.ai/papers/10.1093/bioinformatics/17.2.149
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Li, M., Badger, J. H., Chen, X., Kwong, S., Kearney, P., & Zhang, H. (2001). An information-based sequence distance and its application to whole mitochondrial genome phylogeny. Bioinformatics. https://doi.org/10.1093/bioinformatics/17.2.149

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