The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Characterization of the folding degree of proteins
Open accessAbstract
Motivation: The characterization of the folding degree of chains is central to the elucidation of structure--function relationships in proteins. Here we present a new index for characterizing the folding degree of a (protein) chain. This index shows a range of features that are desirable for the study of the relation between structure and function in proteins. Results: A novel index characterizing the folding degree of (protein) chains is developed based on the spectral moments of a matrix representing the dihedral angles (φ, ω and ε) of the protein main chain. The proposed index is normalized to the chain size, is not correlated to the gyration radius of the backbone chain and is able to distinguish between structures for which the sum of the main-chain dihedral angles is identical. The index is well correlated to the percentages of helix and strand in proteins, shows a linear dependence with temperature changes, and is able to differentiate among protein families. Availability: On request from the author. Contact: estrada66@yahoo.com
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Kabsch, W., & Sander, C. (1983) · Biopolymers · doi:10.1002/bip.360221211 · Cited by 15,320
Introduction to Physical Polymer Science
Sperling, L. H. (2005) · doi:10.1002/0471757128 · Cited by 2,917
The relation between the divergence of sequence and structure in proteins.
Chothia, C., & Lesk, A. M. (1986) · The EMBO Journal · doi:10.1002/j.1460-2075.1986.tb04288.x · Cited by 2,458
Cited by
Some New Trends in Chemical Graph Theory
García-Domenech, R., Gálvez, J., de Julián-Ortiz, J. V., & Pogliani, L. (2008) · Chemical Reviews · doi:10.1021/cr0780006 · Cited by 302
Metadata
- Authors
- Estrada, E.
- Venue
- Bioinformatics
- Publisher
- Oxford University Press (OUP)
- Published
- 2002-05-01
- Volume
- 18
- Issue
- 5
- Pages
- 697-704
- ISSN
- 1367-4803 (ISSN-L)
- 1367-4811
- OpenAlex
- W2164412882
- Cited by
- 209
- References
- 3
- FWCI
- 1.19
- Type
- journal article
- Language
- en
- Open access
- bronze
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