The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.
Imaging genomics
Abstract
The recent completion of a working draft of the human genome sequence promises to provide unprecedented opportunities to explore the genetic basis of individual differences in complex behaviours and vulnerability to neuropsychiatric illness. Functional neuroimaging, because of its unique ability to assay information processing at the level of brain within individuals, provides a powerful approach to such functional genomics. Recent fMRI studies have established important physiological links between functional genetic polymorphisms and robust differences in information processing within distinct brain regions and circuits that have been linked to the manifestation of various disease states such as Alzheimer's disease, schizophrenia and anxiety disorders. Importantly, all of these biological relationships have been revealed in relatively small samples of healthy volunteers and in the absence of observable differences at the level of behaviour, underscoring the power of a direct assay of brain physiology like fMRI in exploring the functional impact of genetic variation.
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Cites
Initial sequencing and analysis of the human genome
International Human Genome Sequencing Consortium, Whitehead Institute for Biomedical Research, C. F. G. R., Lander, E. S., Linton, L. M., Birren, B., Nusbaum, C., Zody, M. C., Baldwin, J., Devon, K., Dewar, K., et al. (2001) · Nature · doi:10.1038/35057062 · Cited by 24,216
The sequence of the human genome
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Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's disease
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The amygdala: vigilance and emotion
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Effect of COMT Val 108/158 Met genotype on frontal lobe function and risk for schizophrenia
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Self-citationSerotonin transporter genetic variation and the response of the human amygdala.
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Self-citationTemporal dynamics of brain activation during a working memory task
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Cited by
Discovering Endophenotypes for Major Depression
Hasler, G., Drevets, W. C., Manji, H. K., & Charney, D. S. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300506 · Cited by 1,123
Hariri, A. R., Goldberg, T. E., Mattay, V. S., Kolachana, B. S., Callicott, J. H., Egan, M. F., & Weinberger, D. R. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-17-06690.2003 · Cited by 1,045
Self-citationThe ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data
the Alzheimer’s Disease Neuroimaging Initiative, E. C., Thompson, P. M., Stein, J. L., Medland, S. E., Hibar, D. P., Vasquez, A. A., Renteria, M. E., Toro, R., Jahanshad, N., Schumann, G., et al. (2014) · Brain Imaging and Behavior · doi:10.1007/s11682-013-9269-5 · Cited by 838
Serotonin Transporter (5-HTTLPR) Genotype and Amygdala Activation: A Meta-Analysis
Munafò, M. R., Brown, S. M., & Hariri, A. R. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.08.016 · Cited by 789
Self-citationTypologies of attentional networks
Raz, A., & Buhle, J. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1903 · Cited by 706
Metadata
- Authors
- Hariri, A. R., & Weinberger, D. R.
- Venue
- British Medical Bulletin
- Publisher
- Oxford University Press (OUP)
- Published
- 2003-03-01
- Volume
- 65
- Issue
- 1
- Pages
- 259-270
- ISSN
- 0007-1420 (ISSN-L)
- 1471-8391
- OpenAlex
- W4243810761
- Cited by
- 292
- References
- 43
- FWCI
- 10.38
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
