The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.
Diffusion-weighted and perfusion MRI demonstrates parenchymal changes in complex partial status epilepticus
Abstract
Diffusion-weighted MRI (DWI) and perfusion MRI (PI) have been mainly applied in acute stroke, but may provide information in the peri-ictal phase in epilepsy patients. Both transient reductions of brain water diffusion, namely a low apparent diffusion coefficient (ADC), and signs of hyperperfusion have been reported in experimental and human epilepsy case studies. We studied 10 patients with complex partial status epilepticus (CPSE) with serial MRI including DWI and PI. All patients showed regional hyperintensity on DWI, and a reduction of the ADC in (i) the hippocampal formation and the pulvinar region of the thalamus (six out of 10 patients), (ii) the pulvinar and cortical regions (two out of 10), (iii) the hippocampal formation only (one out of 10), and (iv) the hippocampal formation, the pulvinar and the cortex (one out of 10). In all patients a close spatial correlation of focal hyperperfusion with areas of ADC/DWI change was present. In two patients hyperperfusion was confirmed in additional SPECT (single photon emission computed tomography) studies. All patients received follow-up MRI examinations showing partial or complete resolution of diffusion and perfusion abnormalities depending on the length of the follow-up interval. The clinical course, EEG and SPECT results all indicate that MRI detected changes related to prolonged epileptic activity. Combined PI and DWI can visualize haemodynamic and tissue changes after CPSE in the hippocampus, thalamus and affected cortical regions.
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Cites
EPILEPSY AND THE FUNCTIONAL ANATOMY OF THE HUMAN BRAIN
Penfield, W., & Jasper, H. (1954) · Southern Medical Journal · doi:10.1097/00007611-195407000-00024 · Cited by 4,092
Østergaard, L., Weisskoff, R. M., Chesler, D. A., Gyldensted, C., & Rosen, B. R. (1996) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910360510 · Cited by 1,512
The functional logic of cortico-pulvinar connections
Shipp, S. (2003) · Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rstb.2002.1213 · Cited by 411 · cited 1×
“This phenomenon on DWI in an acute peri-ictal state provides further evidence for a potential role of anatomical connections between the thalamus and mesial temporal lobe structures in symptomatic epilepsy and may add to the understanding of the extensive pulvinocortical relationships (Shipp, 2003).”
MRI abnormalities associated with partial status epilepticus
Lansberg, M. G., O’Brien, M. W., Norbash, A. M., Moseley, M. E., Morrell, M., & Albers, G. W. (1999) · Neurology · doi:10.1212/wnl.52.5.1021 · Cited by 360
Kim, J., Chung, J. I., Yoon, P. H., Kim, D. I., Chung, T., Kim, E., & Jeong, E. (2001) · PubMed Central · Cited by 314
Functional magnetic resonance imaging of focal seizures
Jackson, G. D., Connelly, A., Cross, J. H., Gordon, I., & Gadian, D. G. (1994) · Neurology · doi:10.1212/wnl.44.5.850 · Cited by 212
THE EVIDENCE FOR A CEREBRAL VASCULAR MECHANISM IN EPILEPSY
Penfield, W. G. (1933) · Annals of Internal Medicine · doi:10.7326/0003-4819-7-3-303 · Cited by 149
Detre, J. A., Sirven, J. I., Alsop, D. C., O’Connor, M. J., & French, J. A. (1995) · Annals of Neurology · doi:10.1002/ana.410380410 · Cited by 140
Diffusion changes in status epilepticus
Wieshmann, U. C., Symms, M. R., & Shorvon, S. D. (1997) · The Lancet · doi:10.1016/s0140-6736(05)63083-8 · Cited by 138
Fabene, P. F., Marzola, P., Sbarbati, A., & Bentivoglio, M. (2003) · NeuroImage · doi:10.1016/s1053-8119(02)00025-3 · Cited by 131
Metadata
- Authors
- Szabo, K., Poepel, A., Pohlmann-Eden, B., Hirsch, J., Back, T., Sedlaczek, O., Hennerici, M., & Gass, A.
- Venue
- Brain
- Publisher
- Oxford University Press (OUP)
- Published
- 2005-03-02
- Volume
- 128
- Issue
- 6
- Pages
- 1369-1376
- ISSN
- 0006-8950 (ISSN-L)
- 1460-2156
- OpenAlex
- W2150163312
- Cited by
- 334
- References
- 21
- FWCI
- 10.26
- Type
- journal article
- Language
- en
- Open access
- closed
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- Szabo, K., Poepel, A., Pohlmann-Eden, B., Hirsch, J., Back, T., Sedlaczek, O., Hennerici, M., & Gass, A. (2005). Diffusion-weighted and perfusion MRI demonstrates parenchymal changes in complex partial status epilepticus. Brain. https://doi.org/10.1093/brain/awh454
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