Therapeutic effects of glatiramer acetate and grafted CD115+monocytes in a mouse model of Alzheimer’s disease
Koronyo, Yosef, Salumbides, Brenda C., Sheyn, Julia, Pelissier, Lindsey, Li, Songlin, Ljubimov, Vladimir, Moyseyev, Michelle, Daley, David, Fuchs, Dieu-Trang, Pham, Michael, Black, Keith L., Rentsendorj, Altan, Koronyo-Hamaoui, Maya·2015·Brain
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- Foveal Avascular Zone and Choroidal Thickness Are Decreased in Subjects with Hard Drusen and without High Genetic Risk of Developing Alzheimer’s DiseaseInés López‐Cuenca, Rosa de Hoz, Celia Alcántara‐Rey, Elena Salobrar‐García, Lorena Elvira‐Hurtado, José A. Fernández‐Albarral, Ana Barabash, Federico Ramírez‐Toraño, Jaisalmer de Frutos‐Lucas, Juan Jose Salazar et al. · 2021 · Biomedicines
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- Interleukin-4 promotes the clearance of amyloid-β by monocyte through enhancing the recognition and intracellular processing of amyloid-βSihan Chen, Yuan Cheng, Yan‐Jiang Wang, Yi-Fei Ji · 2024 · Journal of Alzheimer s Disease
- The Role of T Cells in Alzheimer's Disease PathogenesisJin Zhao, Xiaofang Wang, Yusheng He, Pingyi Xu, Laijun Lai, Younggie Chung, Xinghua Pan · 2023 · Critical Reviews in Immunology
- The effects of high plasma levels of Aβ1-42 on mononuclear macrophage in mouse models of Alzheimer’s diseaseChunrong Li, Kangding Liu, Jie Zhu, Feiqi Zhu · 2023 · Immunity & Ageing
- Assessing the In Vitro Potential of Glatiramer Acetate (Copaxone®) as a Chemotherapeutic Candidate for the Treatment of Cryptococcus neoformans InfectionVinícius Alves, Pedro Martins, Bruna Porpino Miranda, Iara Bastos de Andrade, Luiza Pereira, Christina Takiya Maeda, Glauber Ribeiro de Sousa Araújo, Susana Frasés · 2023 · Journal of Fungi
- Treatment with glatiramer acetate in APPswe/PS1dE9 mice at an early stage of Alzheimer’s disease prior to amyloid-beta deposition delays the disease’s pathological development and ameliorates cognitive declineZengyong Huang, Zhuo Gong, Yongtai Lin, Fan Yang, Weiping Chen, Shaotong Xiang, Yuedong Huang, Hao Xiao, Shuwen Xu, Jinhai Duan · 2024 · Frontiers in Aging Neuroscience
- Quantifying miRNA Deregulation in Alzheimer’s DiseaseAna Luísa Cardoso, Joana Ribeiro Guedes · 2018 · Methods in molecular biology
- Alzheimer’s disease causes bone marrow myelopoiesis dysfunctionMiguel Angel Abellanas, Leyre Basurco, Maitreyee Purnapatre, Chiara Burgaletto, Giulia Castellani, Sarah Phoebeluc Colaiuta, Javier María Peralta Ramos, Angham Ibraheem, Sama Murad, Paola Antonello et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Inconsistent Effects of Glatiramer Acetate Treatment in the 5xFAD Mouse Model of Alzheimer’s DiseaseBerke Karaahmet, John A. Olschowka, M. Kerry O’Banion · 2023 · Pharmaceutics
- Correlation between Blood Monocytes and CSF Tau in Alzheimer’s Disease: The Effect of Gender and Cognitive DeclineCarlotta Ginevra Valentina Cimiotti, Paolo Paganetti, Stefania Rossi, Emiliano Soldini, Leonardo Sacco · 2023 · NeuroSci
- Advances in Retinal Imaging: Retinal Amyloid ImagingMaya Koronyo‐Hamaoui, Jonah Doustar, Mia Oviatt, Keith L. Black, Yosef Koronyo · 2020 · Springer eBooks
- Targeting glial PD-1/PD-L1 restores microglial homeostasis and attenuates neuronal hyperactivity in an Alzheimer’s disease modelTaeyoung Park, Leechung Chang, Seung Won Chung, Seowoo Lee, Sungjun Bae, Carlo Condello, Yong Ho Kim, Jaecheol Lee, Han-Joo Kim, Ho-Keun Kwon et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Therapeutic effect of systemic use of glatiramer acetate in imiquimod-induced mouse psoriasis modelGoknur Demiran, Rukiye Yasak Güner, Mustafa Ozkara, Mustafa Tosun, Melih Akyol · 2025 · Cutaneous and Ocular Toxicology
- Contribution of “Genuine Microglia” to Alzheimer's Disease PathologySadayuki Hashioka, Ken Inoue, Koji Otsuki, Maiko Hayashida, Rei Wake, Noriyuki Kawano, Haruo Takeshita, Masatoshi Inagaki · 2022 · Frontiers in Aging Neuroscience
- Systemic inflammation in relation to exceptional memory in the Long Life Family Study (LLFS)Ruhee A. Patel, Stephanie Cosentino, Esther Zhiwei Zheng, Nicole Schupf, Sandra Barral, Mary Furlan Feitosa, Stacy L. Andersen, Paola Sebastiani B, Svetlana V. Ukraintseva, Kaare Christensen et al. · 2024 · Brain Behavior & Immunity - Health
- The Expression of Activin Receptor-Like Kinase 1 (ACVRL1/ALK1) in Hippocampal Arterioles Declines During Progression of Alzheimer’s DiseaseKelley E. Anderson, Thomas A. Bellio, Emily Aniskovich, Stephanie L. Adams, Jan Krzysztof Blusztajn, Ivana Delalle · 2020 · Cerebral Cortex Communications
- Fighting Chronic Neuroinflammation by Boosting AutoimmunityMichal Schwartz, Kuti Baruch · 2016 · Elsevier eBooks
- Influence of lithium in neuron-glia interaction in hippocampal neuronsNicole Kemberly Ribeiro Rocha, Orestes Vicente Forlenza, Daniel S. Kerr, Helena Brentani, Vanessa de Jesus Rodrigues de Paula · 2018 · Revista de Medicina
- Neuroprotective and Neurorestorative Properties of Copolymer-1: Its Immunomodulating Effects on Ischemic StrokeYolanda Cruz, Melanie Tessa Saavedra Navarrete, José Juan Antonio Ibarra Arias · 2020 · IntechOpen eBooks
- Glia maturation factor-γ regulates amyloid-β42 phagocytosis through scavenger receptor class A type I in murine macrophagesWulin Aerbajinai, Jianqiong Zhu, Kyung Chin, Griffin P. Rodgers · 2024 · Journal of Leukocyte Biology
- Epigenetic derepression of H3K9me3 mitigates Alzheimer-related pathology and improves cognition via immunomodulation and Vgf inductionDieu-Trang S. Fuchs, Jean‐Philippe Vit, Altan Rentsendorj, Julia Sheyn, Haoshen Shi, Yosef Koronyo, Oksana M. Chepurna, Miyah R. Davis, Jered W. Wilson, Lon S. S. Schneider et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Early-Life Systemic Inflammation Modulate Microglia Phenotype to Slow Down Aβ Pathology in the 5xFAD Mouse Model of Alzheimer’s DiseaseYiyi Yang, Marta García-Cruzado, Hairuo Zeng, Xinrui Wang, Sara Bachiller, Lluís Camprubí-Ferrer, Bazhena Bahatyrevich-Kharitonik, Rosalía Fernández‐Calle, Tomas Deierborg · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Molecular mechanism decipher of Alzheimer’s disease based on single-cell RNA-seq informationXue Jiang, Dong-Qing Wei, Jing Ye, Éric Gilson · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Additional file 5 of Key role of the CCR2-CCL2 axis in disease modification in a mouse model of tauopathyHila Ben-Yehuda, Michal Arad, Javier María Peralta Ramos, Sharon, Efrat, Giulia Castellani, Shir Ferrera, Liora Cahalon, Sarah Phoebeluc Colaiuta, Salame, Tomer-Meir, Schwartz, Michal · 2021 · Figshare
- Additional file 3 of Key role of the CCR2-CCL2 axis in disease modification in a mouse model of tauopathyHila Ben-Yehuda, Michal Arad, Javier María Peralta Ramos, Sharon, Efrat, Giulia Castellani, Shir Ferrera, Liora Cahalon, Sarah Phoebeluc Colaiuta, Salame, Tomer-Meir, Schwartz, Michal · 2021 · Figshare
- Additional file 4 of Key role of the CCR2-CCL2 axis in disease modification in a mouse model of tauopathyHila Ben-Yehuda, Michal Arad, Javier María Peralta Ramos, Sharon, Efrat, Giulia Castellani, Shir Ferrera, Liora Cahalon, Sarah Phoebeluc Colaiuta, Salame, Tomer-Meir, Schwartz, Michal · 2021 · Figshare
- Additional file 2 of Key role of the CCR2-CCL2 axis in disease modification in a mouse model of tauopathyHila Ben-Yehuda, Michal Arad, Javier María Peralta Ramos, Sharon, Efrat, Giulia Castellani, Shir Ferrera, Liora Cahalon, Sarah Phoebeluc Colaiuta, Salame, Tomer-Meir, Schwartz, Michal · 2021 · Figshare
- Additional file 1 of Key role of the CCR2-CCL2 axis in disease modification in a mouse model of tauopathyHila Ben-Yehuda, Michal Arad, Javier María Peralta Ramos, Sharon, Efrat, Giulia Castellani, Shir Ferrera, Liora Cahalon, Sarah Phoebeluc Colaiuta, Salame, Tomer-Meir, Schwartz, Michal · 2021 · Figshare
- Additional file 6 of Key role of the CCR2-CCL2 axis in disease modification in a mouse model of tauopathyHila Ben-Yehuda, Michal Arad, Javier María Peralta Ramos, Sharon, Efrat, Giulia Castellani, Shir Ferrera, Liora Cahalon, Sarah Phoebeluc Colaiuta, Salame, Tomer-Meir, Schwartz, Michal · 2021 · Figshare
- Memantine mitigates radiation-induced cognitive impairment by modulating AKT/GSK3β signalingHao Fu, J. H. Feng, Xiaohong Zhang, Liuxin Tian, Simin Sun, Hongyu Bo, Chengyu He, Xu Wang · 2026 · Radiation and Environmental Biophysics
- H3K9me3 inhibition reverses Alzheimer′s progression by restoring synaptic and immune proteostasis across the brain–retina axisMaya Koronyo‐Hamaoui, Dieu-Trang S. Fuchs, Jean‐Philippe Vit, Altan Rentsendorj, Yosef Koronyo, Julia Sheyn, Bhakta Prasad Gaire, Saba Shahin, Haoshen Shi, Oksana M. Chepurna et al. · 2026 · Research Square
- Rôle de la neuroinflammation et du récepteur microglial TREM2 dans la progression de deux modèles de tauopathieAudrey Vautheny · 2019 · theses.fr (ABES)
- Nuclear accumulation of PANK4 in hippocampal astrocytes aggravates cuproptosis in association with mild cognitive impairment in aged miceBo Wang, Jing Zhang, Chang-Hong Li, Xiao Huang, Ruo‐Bing Gao, Yan Peng, Qing Xie, Ya‐Lei Ning, Yan Zhao, Nan Yang et al. · 2026 · Frontiers in Aging Neuroscience
- Systemic association between aging and Alzheimer′s disease: From shared mechanisms to multi-target interventionsQiu Jiang, Yan-Jiang WANG · 2026 · Shengming kexue
- Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease SeverityAltan Rentsendorj, Jean‐Philippe Vit, A. Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barrón, Anthony Rodriguez, Ousman Jallow, Julia Sheyn et al. · 2026 · Advanced Science
- Bone marrow myelopoiesis dysfunction in Alzheimer’s disease limits monocyte homing to the brain and drives disease progressionMiguel Angel Abellanas, Leyre Basurco, Maitreyee Purnapatre, Chiara Burgaletto, Giulia Castellani, Sarah Phoebeluc Colaiuta, Javier María Peralta Ramos, Angham Ibraheem, Sama Murad, Paola Antonello et al. · 2026 · Nature Neuroscience
- Targeting glial PD-1/PD-L1 restores microglial homeostasis and reduces neuronal hyperactivity in an Alzheimer’s disease modelTaeyoung Park, Leechung Chang, Seung Won Chung, Seowoo Lee, Sungjun Bae, Carlo Condello, Yong Ho Kim, Jaecheol Lee, Han-Joo Kim, Ho‐Keun Kwon et al. · 2026 · Science Advances
- MAFG as a Redox‐Sensitive Node Linking Peripheral Immune Reprogramming to Cognitive Risk in the Sepsis‐to‐Alzheimer's Disease Continuum: Single‐Cell Dissection and Adoptive‐Transfer ValidationXiaoyu Xiang, Tingting Li, Zhongxue Feng, Jing Yang, Zhiwen Gong, Lietao Wang, Lijun Wang, Wei Zhang · 2026 · CNS Neuroscience & Therapeutics
- H3K9me3 inhibition reverses Alzheimer's progression by restoring synaptic and immune proteostasis across the brain–retina axisD. Fuchs, Jean-Philippe Vit, A. Rentsendorj, Yosef Koronyo, J. Sheyn, B. Gaire, Saba Shahin, Hao-Shen Shi, O. Chepurna, M. R. Davis et al. · 2026 · Alzheimer's & Dementia