Reconstruction of single cortical projection neurons reveals primary spine loss in multiple sclerosis
Jürgens, Tanja, Jafari, Mehrnoosh, Kreutzfeldt, Mario, Bahn, Erik, Brück, Wolfgang, Kerschensteiner, Martin, Merkler, Doron·2016·Brain
Cited by (175)
Items 101–175 of 175
- Glial Activity Load on PET Reveals Persistent “Smoldering” Inflammation in MS Despite Disease-Modifying TreatmentTarun Singhal, Steven Cicero, Eero Rissanen, John Ficke, Preksha Kukreja, Steven Vaquerano, Bonnie I. Glanz, Shipra Dubey, William Sticka, Kyle Seaver et al. · 2024 · Clinical Nuclear Medicine
- SV2A-PET imaging uncovers cortical synapse loss in multiple sclerosisEmily M. Ullrich Gavilanes, Laura M. Bartos, Jonathan A. Gernert, Carla Ares Carral, Diego Ruiz Navarro, Joachim B. Havla, Lisa Ann Gerdes, Johannes S. Gnörich, Lea H. Kunze, Julia S. Dorneich et al. · 2025 · Science Translational Medicine
- Alterations of the axon initial segment in multiple sclerosis grey matterAysegul Dilsizoglu Senol, Giulia Pinto, Maxime Beau, Vincent Guillemot, Jeffrey L. Dupree, Christine Stadelmann, Jonas Ranft, Catherine Lubetzki, Marc Davenne · 2022 · Brain Communications
- Complement tunes glutamate release and supports synaptic impairments in an animal model of multiple sclerosisGuendalina Olivero, Alice Taddeucci, Giulia Vallarino, Hanna Trebesova, Alessandra Roggeri, Maria Cristina Gagliani, Katia Cortese, Massimo Grilli, Anna Pittaluga · 2024 · British Journal of Pharmacology
- Immune-directed therapies in MS — efficacy and limitationsBernhard Hemmer, Mark Mühlau · 2017 · Nature Reviews Neurology
- Cuprizone as a model of myelin and axonal damageStella Nyamoya, Felix Schweiger, Markus Kipp, Tanja Hochstrasser · 2017 · Drug Discovery Today Disease Models
- Multiple SclerosisMassimo Filippi, Maria Assunta Rocca · 2020 · Springer eBooks
- Novel SNARE Complex Polymorphisms Associated with Multiple Sclerosis: Signs of Synaptopathy in Multiple SclerosisOsman Özgür Yalın, Tuba Edgünlü, Sevim Çelik, Ufuk Emre, Taşkın Güneş, Yüksel Erdal, Aysun Ünal · 2019 · Balkan Medical Journal
- Decreased number and increased volume with mitochondrial enlargement of cerebellar synaptic terminals in a mouse model of chronic demyelinationHuy Bang Nguyen, Yang Sui, Truc Quynh Thai, Kazuhiro Ikenaka, Toshiyuki Oda, Nobuhiko Ohno · 2018 · Medical Molecular Morphology
- Extracellular Vesicles From Multiple Sclerosis White Matter Exhibit Synaptic, Mitochondrial, Complement and Ageing‐Related Pathway DysregulationLarissa Jank, Madathiparambil Kumaran Satheesh Kumar, Taekyung Ryu, Rohit Thapa, Olesia A. Gololobova, Timothy D. Niepokny, Peter A. Calabresi, Kenneth Whitaker Witwer, Ranjan Dutta, Chan Hyun Na et al. · 2025 · Journal of Extracellular Vesicles
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- Oligodendrocyte and Myelin Pathophysiology in Multiple SclerosisEneritz López-Muguruza, Carla Peiró-Moreno, Asier Ruiz, Carlos Matute · 2025 · Advances in neurobiology
- Pathology and Pathogenesis of Progressive Multiple Sclerosis: Concepts and ControversiesAdrian-Minh Schumacher, Christoph Friedrich Mahler, Martin Kerschensteiner · 2017 · Neurology International Open
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- Early Synapse-Specific Alterations of Photoreceptor Mitochondria in the EAE Mouse Model of Multiple SclerosisDalia Ibrahim, Karin Schwarz, Shweta Suiwal, Sofia Maragkou, Frank Schmitz · 2025 · Cells
- Multiple sclerosis: what have we learned and can we still learn from electron microscopyWendy Oost, Jan F. Meilof, Wia Baron · 2025 · Cellular and Molecular Life Sciences
- Synaptic Density in Multiple SclerosisAmelie Luoma, Markus Matilainen, Jouni Tuisku, Richard Aarnio, Taru Nikkilä, Sini Laaksonen, Mikko Koivumäki, Eveliina Honkonen, Marjo Nylund, Saara Wahlroos et al. · 2025 · Neurology Neuroimmunology & Neuroinflammation
- Thioctamer: a novel thioctic acid–glatiramer acetate nanoconjugate expedites wound healing in diabetic ratsNabil A. Alhakamy, Gamal Abdallah Mohamed, Usama Ahmed Fahmy, Basma Ghazi Eid, Mohammed Wanees Al-Rabia, Amgad I. M. Khedr, Mohammed Z. Nasrullah, Sabrin R. M. Ibrahim, Ashraf B. Abdel‐Naim, Osama A. A. Ahmed et al. · 2022 · Drug Delivery
- Fibroblast growth factor 9 (FGF9)‐mediated neurodegeneration: Implications for progressive multiple sclerosis?Katja Thümmler, Claudia Wrzos, Jonas Franz, Daniel McElroy, John J Cole, Lorna Hayden, Diana Arseni, Friedrich Schwarz, Andreas Junker, Julia M. Edgar et al. · 2023 · Neuropathology and Applied Neurobiology
- Subventricular Zone Microstructure in Pediatric‐Onset Multiple SclerosisMonica Margoni, Loredana Storelli, Elisabetta Pagani, Paolo Preziosa, Damiano Mistri, Mor Gueye, Martina Rubin, Lucia Moiola, Massimo Filippi, Maria Assunta Rocca · 2025 · Annals of Neurology
- Sex differences in the neuronal transcriptome and synaptic mitochondrial function in the cerebral cortex of a multiple sclerosis modelNoriko Itoh, Yuichiro Itoh, Linsey Stiles, Rhonda R. Voskuhl · 2023 · Frontiers in Neurology
- That Wasn’t a Complement—Too Much C3 in Demyelinating DiseaseWendy Xin, Jonah R. Chan · 2020 · Immunity
- Astroglial modulation of synaptic function in the non-demyelinated cerebellar cortex is dependent on MyD88 signaling in a model of toxic demyelinationMelanie Lohrberg, Lena Sünke Mortensen, Carolina Thomas, Franziska Fries, Franziska van der Meer, Alexander A. Götz, Carolin Landt, Hong Jun Rhee, JeongSeop Rhee, David Gómez‐Varela et al. · 2025 · Journal of Neuroinflammation
- Rehabilitation on a treadmill induces plastic changes in the dendritic spines of spinal motoneurons associated with improved execution after a pharmacological injury to the motor cortex in ratsNallely Vázquez-Hernández, Néstor I. Martínez-Torres, Aldo Rafael Tejeda-Martínez, Mario Eduardo Flores-Soto, Hermelinda Salgado‐Ceballos, Ignacio González‐Burgos · 2022 · Journal of Chemical Neuroanatomy
- Antiglutamatergic therapy for multiple sclerosis?Reinhard Hohlfeld, Martin Kerschensteiner · 2016 · The Lancet Neurology
- Endogenous repair and development inspired therapy of neurodegeneration in progressive multiple sclerosisEthan W. Hollingsworth, Jamil Khouri, Jaime Imitola · 2017 · Expert Review of Neurotherapeutics
- DCLK-1 LEVEL IN MULTIPLE SCLEROSIS PATIENTS AND ITS CORRELATION WITH CLINICFatma Şimşek, Nurinnisa Öztürk · 2020 · Multiple Sclerosis and Related Disorders
- Pathology of Multiple SclerosisJordon Dunham, Kedar R. Mahajan · 2021 · Springer eBooks
- Meningeal Lymphatic System-Driven Nanodelivery Unlocks Ursolic Acid’s Pleiotropic Benefits To Optimize Multiple Sclerosis TreatmentXiyu Yang, Ran Meng, Xuan Liu, Yixian Li, Tianying Wang, Ziliang Yan, Lingling Zhou, Xinyi Zhang, Peng Yang, Qizhi Zhang · 2026 · ACS Nano
- Glucosamine/chitosan blend surface-engineered rutin-loaded polymer/lipid hybrid nanoparticles for neuroprotection in induced schizophrenia modelAbeer Salama, Rania Elgohary, Alaa Hamed Salama, Heba Elmotasem · 2026 · Scientific Reports
- Synaptic pathology in multiple sclerosis: a role for Nogo-A signaling in astrocytes?Sheila Espírito‐Santo, Vinícius G Coutinho, Flávia Carvalho Alcântara Gomes · 2022 · Neural Regeneration Research
- Dissecting brain grey and white matter microstructure: a novel clinical diffusion MRI protocolSimona Schiavi, Marco Palombo, Domenico Zacà, Francesco Tazza, Caterina Lapucci, Lucio Castellan, Mauro Costagli, Matilde Inglese · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Biomarkers and Disease Activity in Multiple Sclerosis : A cohort study on patients with clinically isolated syndrome and relapsing remitting multiple sclerosisIrene Håkansson · 2019 · Linköping University medical dissertations
- Imaging the execution phase of neuroinflammatory disease modelsAdrian-Minh Schumacher, Thomas Misgeld, Martin Kerschensteiner, Nicolas Snaidero · 2019 · Experimental Neurology
- Neuroplasticity and Its Relevance for Multiple SclerosisMartin Kerschensteiner · 2017 · Neurodegenerative Disease Management
- ImmunopathogenesisP. Coyle · 2019 · Clinical Neuroimmunology
- A Review of Multiple Sclerosis as an Infectious SyndromeCharles W. Stratton · 2016 · Journal of Neurology & Neurophysiology
- Pathologie und Pathogenese der progredienten Multiplen Sklerose: Konzepte und KontroversenAdrian-Minh Schumacher, Christoph Friedrich Mahler, Martin Kerschensteiner · 2017 · Aktuelle Neurologie
- Demyelination induces selective vulnerability of inhibitory networks in multiple sclerosisLida Zoupi, Sam A. Booker, Dimitri Eigel, Carsten Werner, Peter C. Kind, Tara L. Spires‐Jones, Ben Newland, Anna Williams · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Mediterranean Pattern Diet in Multiple Sclerosis: A Review Focusing on ImmunometabolitesGiulio Papiri, Cristina Paci, Giordano D’Andreamatteo, Valentina Membrino, Tiziana Di Crescenzo, Gabriella Cacchiò, Claudia Cagnetti, Arianna Vignini · 2025 · Current Neuropharmacology
- Silent Synapses in Multiple Sclerosis: From Synaptic Dysfunction to Reactivation‐Based Therapies—A Narrative Review of Cognitive and Neuroplasticity OutcomesZinab Alatawi · 2025 · Developmental Neurobiology
- Pilot Study of the Total and Phosphorylated Tau Proteins in Early-Stage Multiple SclerosisIeva Navickaitė, Katryna Pampuščenko, Gintarė Žemgulytė, Diana Bilskienė, Vilmantė Borutaitė, Renata Balnytė · 2024 · Medicina
- The Neuropathology of Progressive Multiple SclerosisNikos Evangelou, Simon Paine, Emma Clare Tallantyre · 2017 · Springer eBooks
- Targeted neurotherapy: evaluating olanzapine-loaded bilosomes in a cuprizone-induced schizophrenia modelAbeer Salama, Asmaa Badawy Darwish, Siham Mostafa Ali El-Shenawy, Marwa Anwar Wagdi · 2025 · International Journal of Pharmaceutics
- Development of a Human Preclinical Platform for the Identification of Neuroprotective CompoundsRaquel Guerrero González, Elif Nur Yılmaz, Stefanie Albrecht, Maurine Fucito, Damiana Pieragostino, Alina D. Schmidt, Simone König, Una FitzGerald, Tanja Kuhlmann · 2025 · European Journal of Neuroscience
- Myelin Maintenance and Addition Regulate Synaptic Plasticity in the Adult Mouse CortexRenee Pepper, Kalina Makowiecki, Kimberley A. Pitman, Raphael Ricci, Angela L. Nicoli, Phuong Tram Nguyen, C. Leigh Blizzard, Ben Emery, Carlie Laura Cullen, Kaylene M. Young · 2026 · Glia
- Immunotherapies in progressive multiple sclerosisTradite Neziraj, Ludwig Kappos, Anne‐Katrin Pröbstel · 2026 · Handbook of clinical neurology
- Modulation of the immunological and neuroinflammatory microenvironment in older people with multiple sclerosisCelia Oreja‐Guevara, Sven Guenther Meuth, Nikos Grigoriadis, Patrick Vermersch, Hans Peter Hartung, Per Soelberg Sørensen, Letizia Leocani, Klaus Schmierer, Ralf Gold, O Fernandez · 2026 · Frontiers in Immunology
- Imaging subtypes reveal distinct biological substrates and disability profiles in multiple sclerosisPaolo Preziosa, Loredana Storelli, Ferdinando Clarelli, Elisabetta Pagani, Nicolò Tedone, Monica Margoni, Federica Esposito, Antonio Gallo, Alessandro d’Ambrosio, Massimo Filippi et al. · 2026 · Brain
- Historical review: The golden age of the Golgi method in human neuropathologyIsidró Ferrer · 2024 · Journal of Neuropathology & Experimental Neurology
- The protective effect of Fingolimod upon visual behavior in a demyelination animal model is associated with synaptopathy preventionAna Carolina de Pádua, Saulo Augusto Alves da Cruz, Luiza dos Santos Heringer, Greice Nascimento Pires, Daniel Areias da Silva Raquita, Jéssica dos Santos Tavares, Pedro Souto Rodrigues, Ana Cecília Dos Santos Guimarães Sá, Cíntia Monteiro de Barros, Sérgio Henrique Seabra et al. · 2025 · NeuroToxicology
- Immunological Tolerance Induced by Nanoliposome with Autoantigenie Peptide and Artesunate to Inhibit Complement and Remodel Immune Balance for Multiple Sclerosis TreatmentYaya Wei, Li Li, Tingting Fu, Ting Gao, Lanlan Ma, Wenbao Zuo, Jianhong Yang · 2025 · Advanced Healthcare Materials
- Unraveling cortical pathology in multiple sclerosis using the T1‐/T2‐weighted ratio?Caterina Mainero, Céline Louapre · 2017 · Annals of Neurology
- Localized calcium accumulations prime synapses for phagocyte removal in cortical neuroinflammationMehrnoosh Jafari, Adrian-Minh Schumacher, Nicolas Snaidero, Tradite Neziraj, Emily M. Ullrich Gavilanes, Tanja Jürgens, Juan Daniel Flórez Weidinger, Stephanie S. Schmidt, Eduardo Beltrán, Nellwyn Hagan et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- Pathologie und PathophysiologieChristine Stadelmann, Wolfgang Brück · 2015 · Elsevier eBooks
- Modulation of remyelination by adaptive inflammation and electrical stimulationKunz, Patrik · 2017
- Much, if not all, of the cortical damage in MS can be attributed to the microglial cell – CommentaryJonathan I Spencer, Gabriele C. DeLuca · 2018 · Multiple Sclerosis Journal
- Experimental models of cortical multiple sclerosis pathologyMaarten E. Witte, Jack van Horssen · 2017 · Drug Discovery Today Disease Models
- Anatomie pathologique de la sclérose en plaques et des maladies apparentéesDanielle Seilhean, Doron Merkler · 2019 · Elsevier eBooks
- a Circulating cell free mitochondrial DNA copy number variation in neurodegenerative diseaseHannah Lowes · 2018
- Pathophysiology of Grey Matter Affection in MSGabriel González‐Escamilla, Dumitru Ciolac · 2021 · Neuromethods
- Literatur2021 · Elsevier eBooks
- Analysis of autoimmune lesions in grey matterMoritz Hermann · 2018
- Alterations of the axon initial segment in multiple sclerosisAysegul Dilsizoglu Senol, Giulia Pinto, Maxime Beau, Vincent Guillemot, Jeffrey L. Dupree, Christine Stadelmann, Jonas Ranft, Catherine Lubetzki, Marc Davenne · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Pathologie und PathophysiologieChristine Stadelmann, Wolfgang Brück · 2018 · Elsevier eBooks
- Місце мікроглії при розсіяному склерозі: мішені та фармакологічна стратегіяО. О. Нефьодов, O. I. Kalbus, N. P. Shastun, Л. О. Чобіток, А А Ефанова, О. П. Максименко, О. В. Широков, Валерій Степура · 2023 · Pharmacology and Drug Toxicology
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- Physiopathologie de la sclérose en plaquesAnne‐Laure Dubessy, Bruno Stankoff · 2025 · Encyclopédie médico-chirurgicale. Neurologie
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