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Human Monkeypox
Abstract
Human monkeypox is a zoonotic Orthopoxvirus with a presentation similar to smallpox. Clinical differentiation of the disease from smallpox and varicella is difficult. Laboratory diagnostics are principal components to identification and surveillance of disease, and new tests are needed for a more precise and rapid diagnosis. The majority of human infections occur in Central Africa, where surveillance in rural areas with poor infrastructure is difficult but can be accomplished with evidence-guided tools and educational materials to inform public health workers of important principles. Contemporary epidemiological studies are needed now that populations do not receive routine smallpox vaccination. New therapeutics and vaccines offer hope for the treatment and prevention of monkeypox; however, more research must be done before they are ready to be deployed in an endemic setting. There is a need for more research in the epidemiology, ecology, and biology of the virus in endemic areas to better understand and prevent human infections.
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Cited by
Clinical features and management of human monkeypox: a retrospective observational study in the UK
Adler, H., Gould, S., Hine, P., Snell, L. B., Wong, W., Houlihan, C. F., Osborne, J. C., Rampling, T., Beadsworth, M. B., Duncan, C. J., et al. (2022) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(22)00228-6 · Cited by 1,256
Gessain, A., Nakoune, E., & Yazdanpanah, Y. (2022) · New England Journal of Medicine · doi:10.1056/nejmra2208860 · Cited by 409
Mpox virus infection and drug treatment modelled in human skin organoids
Li, P., Pachis, S. T., Xu, G., Schraauwen, R., Incitti, R., de Vries, A. C., Bruno, M. J., Peppelenbosch, M. P., Alam, I., Raymond, K., et al. (2023) · Nature Microbiology · doi:10.1038/s41564-023-01489-6 · Cited by 77
Genomic and transcriptomic analysis of the recent Mpox outbreak
Giorgi, F. M., Pozzobon, D., Di Meglio, A., & Mercatelli, D. (2024) · Vaccine · doi:10.1016/j.vaccine.2023.12.086 · Cited by 64
Metadata
- Authors
- McCollum, A. M., & Damon, I. K.
- Venue
- Clinical Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2013-10-24
- Volume
- 58
- Issue
- 2
- Pages
- 260-267
- ISSN
- 1058-4838 (ISSN-L)
- 1537-6591
- OpenAlex
- W4234185093
- Cited by
- 1,086
- References
- 0
- FWCI
- 2.68
- Type
- journal article
- Language
- en
- Open access
- closed
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- McCollum, A. M., & Damon, I. K. (2014). Human Monkeypox. Clinical Infectious Diseases. https://doi.org/10.1093/cid/cit703
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