The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Association of low serum concentration of bilirubin with increased risk of coronary artery disease
Abstract
We examined serum bilirubin and various liver-function enzymes as possible risk factors for angiographically documented coronary artery disease (CAD). The studies involved a "training" set of 619 men for whom complete data on all risk factors considered were available, and a "test" set of 258 men for whom some risk factor data were not available. In both study groups, the liver enzymes were not related to CAD; however, In[total bilirubin] was inversely and statistically significantly related to the presence of CAD, both univariately and multivariately after adjustment for the established risk factors of age, total cholesterol, high-density lipoprotein cholesterol, smoking history, and systolic blood pressure. A 50% decrease in total bilirubin was associated with a 47% increase in the odds of being in a more severe CAD category. Our data suggest that serum bilirubin is an inverse and independent risk factor for CAD, with an association equivalent in degree to that of systolic blood pressure.
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(1990) · Choice Reviews Online · doi:10.5860/choice.27-3338 · Cited by 35,305
Salonen, J. T., Nyyssönen, K., Korpela, H., Tuomilehto, J., Seppänen, R., & Salonen, R. (1992) · Circulation · doi:10.1161/01.cir.86.3.803 · Cited by 1,284
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Doré, S., Takahashi, M., Ferris, C. D., Hester, L. D., Guastella, D., & Snyder, S. H. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.5.2445 · Cited by 699
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Metadata
- Authors
- Schwertner, H. A., Jackson, W. G., & Tolan, G.
- Venue
- Clinical Chemistry
- Publisher
- Oxford University Press (OUP)
- Published
- 1994-01-01
- Volume
- 40
- Issue
- 1
- Pages
- 18-23
- ISSN
- 0009-9147 (ISSN-L)
- 1530-8561
- OpenAlex
- W1862027433
- Cited by
- 474
- References
- 2
- FWCI
- 2.70
- Type
- journal article
- Language
- en
- Open access
- closed
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- Schwertner, H. A., Jackson, W. G., & Tolan, G. (1994). Association of low serum concentration of bilirubin with increased risk of coronary artery disease. Clinical Chemistry. https://doi.org/10.1093/clinchem/40.1.18
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
