The DOI matches its Crossref record.
Dental Infection and the Risk of New Coronary Events: Prospective Study of Patients with Documented Coronary Artery Disease
Abstract
Several recent studies have suggested that dental infections are associated with coronary artery disease. To further elucidate this association, we conducted a prospective 7-year follow-up study of 214 individuals (182 males and 32 females; mean age, 49 years) with proven coronary artery disease who had undergone a dental examination and evaluation for the classic coronary risk factors at entry. The main outcome measures were the incidence of fatal and nonfatal coronary events and overall mortality. Fifty-two patients met the endpoint criteria during follow-up. Dental health was a significant predictor of coronary events when controlled for the following factors: age, sex, socioeconomic status, smoking, hypertension, the number of previous myocardial infarctions, diabetes, body mass index, and serum lipids. Other significant predictors were the presence of diabetes, the number of previous myocardial infarctions, and the body mass index. Our results give further support to the hypothesis that dental infections are a risk factor for coronary events.
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Citations
Cited by
Systemic Diseases Caused by Oral Infection
Li, X., Kolltveit, K. M., Tronstad, L., & Olsen, I. (2000) · Clinical Microbiology Reviews · doi:10.1128/cmr.13.4.547 · Cited by 1,292
Bahekar, A. A., Singh, S., Saha, S., Molnar, J., & Arora, R. (2007) · American Heart Journal · doi:10.1016/j.ahj.2007.06.037 · Cited by 698
Systemic Effects of Periodontitis: Epidemiology of Periodontal Disease and Cardiovascular Disease
Beck, J. D., & Offenbacher, S. (2005) · Journal of Periodontology · doi:10.1902/jop.2005.76.11-s.2089 · Cited by 447
Beck, J. D., Elter, J. R., Heiss, G., Couper, D., Mauriello, S. M., & Offenbacher, S. (2001) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/hq1101.097803 · Cited by 414
Role of Infection as a Risk Factor for Atherosclerosis, Myocardial Infarction, and Stroke
Mattila, K. J., Valtonen, V. V., Nieminen, M. S., & Asikainen, S. (1998) · Clinical Infectious Diseases · doi:10.1086/514570 · Cited by 309
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Metadata
- Authors
- Mattila, K. J., Valtonen, V. V., Nieminen, M., & Huttunen, J. K.
- Venue
- Clinical Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 1995-03-01
- Volume
- 20
- Issue
- 3
- Pages
- 588-592
- ISSN
- 1058-4838 (ISSN-L)
- 1537-6591
- OpenAlex
- W2126628340
- Cited by
- 350
- References
- 0
- FWCI
- 7.40
- Type
- journal article
- Language
- en
- Open access
- closed
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- The paper
- Mattila, K. J., Valtonen, V. V., Nieminen, M., & Huttunen, J. K. (1995). Dental Infection and the Risk of New Coronary Events: Prospective Study of Patients with Documented Coronary Artery Disease. Clinical Infectious Diseases. https://doi.org/10.1093/clinids/20.3.588
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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