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Epidemiology of Cryptococcosis in France: A 9-Year Survey (1985-1993)

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Dromer, F., Mathoulin, S., Dupont, B., Laporte, A., French Cryptococcosis Study Group·1996·Clinical Infectious Diseases

Abstract

We analyzed the data collected during a nationwide survey of cryptococcosis (1985-1993). We first checked the quality of the survey. The stability of its completeness (approximately 50%) and its representativity were assessed by the capture-recapture method after we cross-checked our data on cryptococcosis (as a presenting manifestation of AIDS) against those of the national registry of AIDS. Of the 1,057 cases of cryptococcosis (1,013 patients), 827 (86%) involved patients with AIDS. The increasing number of cases of human immunodeficiency virus (HIV)-related cryptococcosis over time paralleled the AIDS epidemic except for a higher male-to-female ratio. Malignancies (32%), organ transplantation (19%), and corticosteroid therapy (33%) were the main predisposing conditions in 163 patients without AIDS. Cryptococcal meningitis more frequently occurred in patients with AIDS than in HIV-negative patients (P < 10(-6)). Among the 413 isolates available for serotyping, 410 were Cryptococcus neoformans variety neoformans (including 20.5% of serotype D). Three isolates of the variety gattii (serotype B) were recovered from patients without AIDS.

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Metadata

Authors
Dromer, F., Mathoulin, S., Dupont, B., Laporte, A., & French Cryptococcosis Study Group
Venue
Clinical Infectious Diseases
Published
1996-07-01
Volume
23
Issue
1
Pages
82-90
ISSN
  • 1058-4838 (ISSN-L)
  • 1537-6591
OpenAlex
W2058895756
Cited by
240
References
0
FWCI
6.67
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Epidemiology of Cryptococcosis in France: A 9-Year Survey (1985-1993). https://app.cochat.ai/papers/10.1093/clinids/23.1.82
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Dromer, F., Mathoulin, S., Dupont, B., Laporte, A., & French Cryptococcosis Study Group. (1996). Epidemiology of Cryptococcosis in France: A 9-Year Survey (1985-1993). Clinical Infectious Diseases. https://doi.org/10.1093/clinids/23.1.82

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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