The DOI matches its Crossref record.
Adverse Reactions to Trimethoprim-Sulfamethoxazole in Hospitalized Patients
Abstract
Of 1,121 hospitalized recipients of trimethoprim-sulfamethoxazole, 91 (8%) experienced reactions that were attributed to this drug. The most common adverse effects were gastrointestinal upset (3.9%) and skin reactions (3.3%). Serious toxicity attributable to the drug was rare.
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Citations
Cited by
Drug Allergy: An Updated Practice Parameter
(2010) · Annals of Allergy, Asthma & Immunology · doi:10.1016/j.anai.2010.08.002 · Cited by 957
Successful Intermittent Chemoprophylaxis for Pneumocystis carinii Pneumonitis
Hughes, W. T., Rivera, G. K., Schell, M. J., Thornton, D., & Lott, L. (1987) · New England Journal of Medicine · doi:10.1056/nejm198706253162604 · Cited by 398
Cunha, B. A. (2001) · Medical Clinics of North America · doi:10.1016/s0025-7125(05)70309-6 · Cited by 358
Medina, I., Mills, J., Leoung, G., Hopewell, P. C., Lee, B., Modin, G., Benowitz, N., & Wofsy, C. B. (1990) · New England Journal of Medicine · doi:10.1056/nejm199009203231202 · Cited by 320
Considerations when prescribing trimethoprim-sulfamethoxazole
Ho, J. M. W., & Juurlink, D. N. (2011) · Canadian Medical Association Journal · doi:10.1503/cmaj.111152 · Cited by 232
“Simple exanthems and fixed drug eruptions are some of the most common adverse effects of trimethoprim–sulfamethoxazole, occurring in about 3% of hospital inpatients taking the drug.(54) Less common is a classic drug”
Background
Metadata
- Authors
- Jick, H.
- Venue
- Clinical Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 1982-03-01
- Volume
- 4
- Issue
- 2
- Pages
- 426-428
- ISSN
- 1058-4838 (ISSN-L)
- 1537-6591
- OpenAlex
- W2046691378
- Cited by
- 192
- References
- 0
- FWCI
- 5.91
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Adverse Reactions to Trimethoprim-Sulfamethoxazole in Hospitalized Patients. https://app.cochat.ai/papers/10.1093/clinids/4.2.426
- The paper
- Jick, H. (1982). Adverse Reactions to Trimethoprim-Sulfamethoxazole in Hospitalized Patients. Clinical Infectious Diseases. https://doi.org/10.1093/clinids/4.2.426
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
