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Cited by 276

The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.

Mycobacterial Infections in. AIDS Patients, with an Emphasis on the Mycobacterium avium Complex

Young, L. S., Inderlied, C. B., Berlin, O. G., Gottlieb, M. S.·1986·Clinical Infectious Diseases

Abstract

Serious infections caused by the Mycobacterium avium complex (MAC) have been increasingly recognized over the last three decades. However, the epidemic of the acquired immunodeficiency syndrome (AIDS) has increased interest in these infections. Disseminated mycobacterial disease is common in patients with AIDS, and MAC is the predominant bacterial isolate. Indeed, at UCLA Medical Center, MAC organisms are now the predominant isolates in both AIDS- and non-AIDS-associated mycobacterial disease. MAC lung infections have been difficult to treat. Complex regimens employing four to six drugs are not clearly effective and are usually associated with considerable toxicity. Treatment of MAC infections in patients with AIDS has been particularly frustrating, and evidence that treatment can either eradicate disease or prolong life is limited. MAC organisms are invariably resistant to traditional antituberculosis medications. We have examined a variety of other compounds, and our findings, based on both in vitro and animal-model studies, have identified drugs which, when used in combination, are potentially of therapeutic utility.

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Metadata

Authors
Young, L. S., Inderlied, C. B., Berlin, O. G., & Gottlieb, M. S.
Venue
Clinical Infectious Diseases
Published
1986-11-01
Volume
8
Issue
6
Pages
1024-1033
ISSN
  • 1058-4838 (ISSN-L)
  • 1537-6591
OpenAlex
W1975315742
Cited by
276
References
16
FWCI
19.02
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Mycobacterial Infections in. AIDS Patients, with an Emphasis on the Mycobacterium avium Complex. https://app.cochat.ai/papers/10.1093/clinids/8.6.1024
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Young, L. S., Inderlied, C. B., Berlin, O. G., & Gottlieb, M. S. (1986). Mycobacterial Infections in. AIDS Patients, with an Emphasis on the Mycobacterium avium Complex. Clinical Infectious Diseases. https://doi.org/10.1093/clinids/8.6.1024

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.