The Faroese IBD Study: Incidence of Inflammatory Bowel Diseases Across 54 Years of Population-based Data
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BACKGROUND AND AIMS: Inflammatory bowel diseases [IBDs] include Crohn's disease [CD], ulcerative colitis [UC], and IBD unclassified [IBDU]. In 2010 and 2011, the ECCO-EpiCom study found the worldwide highest incidence of inflammatory bowel disease [IBD] in the Faroe Islands: 83 per 100 000 [European Standard Population, ESP]. The present study assessed the long-term time trends in IBD incidence in the Faroese population. METHODS: In this population-based study, data were retrieved from the National Hospital of the Faroe Islands and included all incident cases of CD, UC, and IBDU diagnosed between July 1960 and July 2014. Patients of all ages were included and diagnoses were defined according to the Copenhagen Diagnostic Criteria. RESULTS: A total of 664 incident IBD patients were diagnosed: 113 with CD, 417 with UC, and 134 with IBDU. Of these, 51 [8%] were diagnosed with paediatric-onset IBD. Between 1960 and 1979, a total of 55 persons were diagnosed; 105 in 1980-89; 166 in 1990-99; 180 in 2000-09; and 158 in 2010-14. This represented an increase in the age-standardised IBD incidence rate from 7, 25, 40, and 42 to 74 per 100 000 [ESP]. For CD, the increase was from 1 to 10, for UC from 4 to 44, and for IBDU from 2 to 21 per 100 000 [ESP]. CONCLUSIONS: The high IBD incidence was found to be a relatively new phenomenon. The observed increase is unlikely to be an artefact resulting from, for instance, better registration. Our study indicated a real and increasing disease burden resulting from changing-so far unidentified-exposures.
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The Ceiling Incidence Range in the Western world is 23.8-29.3 per 100,000 for Crohn's disease and 23.1-57.9 per 100,000 for ulcerative colitis.
“For Crohn’s disease, the Ceiling Incidence Range is in the range 23.8–29.3 per 100,000 (refs4,40,43), and for ulcerative colitis, it is in the range 23.1–57.9 per 100,000 (refs4,43,44).”
From The four epidemiological stages in the global evolution of inflammatory bowel disease (2021) · cites this paper as [44]
The Faroe Islands had the highest worldwide average annual incidence of IBD at 84.2 per 100,000 in 2011, with a predominance of ulcerative colitis.
“By contrast, the Danish territory of the Faroe Islands had the highest worldwide average annual incidence of IBD at 84.2 per 100,000 in 2011, with a predominance of ulcerative colitis44.”
From The four epidemiological stages in the global evolution of inflammatory bowel disease (2021) · cites this paper as [44]
The increased incidence of IBD in the Faroe Islands is not simply an artefact of improved awareness, diagnosis, and data capture.
“The investigators articulated an elegant argument that the increased incidence of IBD in the Faroe Islands is not simply an artefact of improved awareness, diagnosis and data capture44.”
From The four epidemiological stages in the global evolution of inflammatory bowel disease (2021) · cites this paper as [44]
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- Authors
- Hammer, T., Nielsen, K. R., Munkholm, P., Burisch, J., & Lynge, E.
- Affiliations
- University of the Faroe Islands (FO)
- University of Copenhagen (DK)
- Corresponding author
- Nielsen, Kári R.
- Venue
- Journal of Crohn's and Colitis
- Publisher
- Oxford University Press (OUP)
- Published
- 2016-03-01
- Volume
- 10
- Issue
- 8
- Pages
- 934-942
- ISSN
- 1873-9946 (ISSN-L)
- 1876-4479
- PMC
- PMC4962362
- OpenAlex
- W2289887585
- Cited by
- 85
- References
- 44
- Citations by year
- 2026: 6 · 2025: 8 · 2024: 7 · 2023: 13 · 2022: 9 · 2021: 7 · 2020: 8 · 2019: 8 · 2018: 11 · 2017: 6 · 2016: 1
- FWCI
- 7.00
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by
- Locations
- Journal of Crohn s and Colitis (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Research at the University of Copenhagen (University of Copenhagen) (publishedVersion, cc-by)
- HighWire Press Open Archive (submittedVersion)
- Funders
- European Crohn's and Colitis Organisation
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Inflammatory Bowel Disease
- Health Sciences › Medicine › Ophthalmology › Ocular Diseases and Behçet’s Syndrome
- Health Sciences › Medicine › Epidemiology › Microscopic Colitis
- Keywords
- inflammatory bowel disease, Crohn's disease
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Denmark, Female, Humans, Infant, Infant, Newborn, Male, Middle Aged, Registries, Inflammatory Bowel Diseases, Incidence, Young Adult
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