Will simultaneous measurement of E/e' index facilitate the non-invasive assessment of left ventricular filling pressure in patients with non-valvular atrial fibrillation?
Abstract
AIMS: The ratio of early transmitral flow velocity (E) to early diastolic mitral annular velocity (e') was applied as a non-invasive index to assess left ventricular filling pressure (LVFP). However, the reliability of E/e' was undermined in patients with atrial fibrillation (AF). Recently, a novel method entitled 'dual Doppler' was established, which allows simultaneous recording and display of E and e'. Our study investigates whether the dual-Doppler method improves the reliability of E/e' in AF patients. METHODS AND RESULTS: Forty-nine patients with non-valvular AF underwent conventional echocardiography, dual-Doppler echocardiography, and cardiac catheterization within 4 h. Of 22 patients (45%c) with increased LVFP (>15 mmHg), higher E/e' measured by both conventional tissue Doppler imaging (TDI) and dual-Doppler method was observed. Conventional echocardiographic variables were correlated with LVFP (E/e'(sep), r = 0.404, E/e'(lat), r = 0.487), but E/e' measured synchronously in the dual-Doppler mode yielded a better correlation (E/e'(synchronous sep), r = 0.754, E/e'(synchronous lat), r = 0.765). The intra- and interobserver variability of the dual-Doppler method was significantly lower than the conventional TDI method. CONCLUSION: Good correlations were found between E/e'' and LVFP in patients with AF, particularly in the dual-Doppler mode. E/e' measured by the dual-Doppler method can therefore be applied to assess diastolic dysfunction in AF patients.
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The ratio of E/e' has demonstrated a significant correlation with invasive measurement of LV filling pressures.
“while the ratio of E/e' has demonstrated a significant correlation with invasive measurement of LV filling pressures.”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [231]
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2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
Kirchhof, P., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castella, M., Diener, H.-C., Heidbuchel, H., Hendriks, J., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw210 · Cited by 6,418 · see citing works
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
Kirchhof, P., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castella, M., Diener, H.-C., Heidbuchel, H., Hendriks, J., et al. (2016) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezw313 · Cited by 1,403 · see citing works
- Authors
- Li, C., Zhang, J., Zhou, C., Huang, L., Tang, H., & Rao, L.
- Affiliations
- West China Hospital of Sichuan University (CN)
- Corresponding author
- Rao, L.
- Venue
- European Journal of Echocardiography
- Publisher
- Oxford University Press (OUP)
- Published
- 2009-12-17
- Volume
- 11
- Issue
- 3
- Pages
- 296-301
- ISSN
- 1525-2167 (ISSN-L)
- 1532-2114
- OpenAlex
- W2125105579
- Cited by
- 42
- References
- 30
- Citations by year
- 2026: 3 · 2024: 2 · 2023: 1 · 2022: 4 · 2021: 4 · 2020: 2 · 2019: 2 · 2018: 4 · 2017: 3 · 2016: 8 · 2015: 2 · 2014: 2 · 2013: 1 · 2012: 1
- FWCI
- 0.86
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Journal of Echocardiography (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Valve Diseases and Treatments
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Keywords
- E/e' ratio, left ventricular filling pressure, non-valvular atrial fibrillation, tissue Doppler imaging, diastolic dysfunction, mitral annular velocity, observer variability
- MeSH terms
- Atrial Fibrillation, Blood Pressure, Echocardiography, Female, Humans, Male, Middle Aged, Sensitivity and Specificity, Stroke Volume, Observer Variation, Ventricular Dysfunction, Left, Echocardiography, Doppler, Color
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