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Binding of the PX domain of p47phox to phosphatidylinositol 3,4‐bisphosphate and phosphatidic acid is masked by an intramolecular interaction
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The PX domain of p47phox possesses synergistic lipid-binding sites, one for PI(3,4)P2 and the other for anionic lipids such as phosphatidic acid and PS.
“The PX domain of p47phox also possesses synergistic lipid‐binding sites, one for PI(3,4)P2 and the other for anionic lipids such as phosphatidic acid and PS (Karathanassis et al, 2002).”
From Molecular basis of accessible plasma membrane cholesterol recognition by the GRAM domain of GRAMD1b (2021) · cites this paper as Karathanassis et al, 2002
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Metadata
- Authors
- Karathanassis, D., Stahelin, R. V., Bravo, J., Perisic, O., Pacold, C. M., Cho, W., & Williams, R. L.
- Venue
- The EMBO Journal
- Published
- 2002-10-01
- Volume
- 21
- Issue
- 19
- Pages
- 5057-5068
- ISSN
- 0261-4189
- 1460-2075
- Cited by
- 294
- References
- 0
- Language
- en
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