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Serine 396 of PDK1 is required for maximal PKB activation

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Stable Government of Mitosis by Greatwall: the Emperor's Best Servant

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Characterization of NimA-related Kinase 10 (NEK10): A Role in Checkpoint Control

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Stimuli That Activate MSK in Cells and the Molecular Mechanism

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Identification and Characterization of a Novel CK2-MSK2 Iinteraction in the UV Response

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PDK1 has a pleiotropic PINOID-independent role in Arabidopsis developmentPreprint

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Exploring the roles of the Protein Kinase N family in breast cancer

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SHP-1 and PDK1 Form a Phosphotyrosine-Dependent Nucleo-Cytoplasmic Shuttling Complex: Implications for Differentiation

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RSK (p90 Ribosomal S6 Kinase)

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Regulation of epidermal growth factor receptor signaling by clathrin-coated membrane microdomains

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Data from Development of a Small-Molecule Serum- and Glucocorticoid-Regulated Kinase-1 Antagonist and Its Evaluation as a Prostate Cancer Therapeutic

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Data from Development of a Small-Molecule Serum- and Glucocorticoid-Regulated Kinase-1 Antagonist and Its Evaluation as a Prostate Cancer Therapeutic

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The signalling pathways allowing hormonal regulation of Na+ transport in murine collecting duct cells

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Etude phénotypique des cellules endométriosiques profondes

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An AGC kinase cascade regulates ROP signaling for the correct timing of pollen germination

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BindingDB Entry 50039198: Design and synthesis of benzoazepin-2-one analogs as allosteric binders targeting the PIF pocket of PDK1.

BindingDB (2012) · UC San Diego · doi:10.7270/q2z60q1h

BindingDB Entry 7800: An Allosteric Inhibitor Scaffold Targeting the PIF-Pocket of Atypical Protein Kinase C Isoforms.

BindingDB (2017) · UC San Diego · doi:10.7270/q2j96575

BindingDB Entry 50030488: 3,5-Diphenylpent-2-enoic acids as allosteric activators of the protein kinase PDK1: structure-activity relationships and thermodynamic characterization of binding as paradigms for PIF-binding pocket-targeting compounds.

BindingDB (2010) · UC San Diego · doi:10.7270/q2fb52zc

BindingDB Entry 6010: PIF-pocket as a target for C. albicans Pkh selective inhibitors.

BindingDB (2014) · UC San Diego · doi:10.7270/q2n878f2

BindingDB Entry 50032234: Turning enzymes ON with small molecules.

BindingDB (2011) · UC San Diego · doi:10.7270/q25q4w9q

BindingDB Entry 5645: Genetic and pharmacological inhibition of PDK1 in cancer cells: characterization of a selective allosteric kinase inhibitor.

BindingDB (2012) · UC San Diego · doi:10.7270/q21c1vgq

BindingDB Entry 7515: Bidirectional Allosteric Communication between the ATP-Binding Site and the Regulatory PIF Pocket in PDK1 Protein Kinase.

BindingDB (2016) · UC San Diego · doi:10.7270/q23n226c

BindingDB Entry 50004390: Structure and allosteric effects of low-molecular-weight activators on the protein kinase PDK1.

BindingDB (2020) · UC San Diego · doi:10.7270/q2v98bxr

BindingDB Entry 2115: Interactions of LY333531 and other bisindolyl maleimide inhibitors with PDK1.

BindingDB (2007) · UC San Diego · doi:10.7270/q2sj1hv2

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The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB

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Mechanism for activation of the growth factor‐activated AGC kinases by turn motif phosphorylation

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