Cited by 160Artificial Intelligence in Healthcare and EducationArtificial Intelligence in HealthcareMachine Learning in Healthcare

Artificial intelligence in cardiovascular medicine: clinical applications

Open access
Lüscher, Thomas F, Wenzl, Florian A, D’Ascenzo, Fabrizio, Friedman, Paul A, Antoniades, Charalambos·2024·European Heart Journal

Abstract

Clinical medicine requires the integration of various forms of patient data including demographics, symptom characteristics, electrocardiogram findings, laboratory values, biomarker levels, and imaging studies. Decision-making on the optimal management should be based on a high probability that the envisaged treatment is appropriate, provides benefit, and bears no or little potential harm. To that end, personalized risk-benefit considerations should guide the management of individual patients to achieve optimal results. These basic clinical tasks have become more and more challenging with the massively growing data now available; artificial intelligence and machine learning (AI/ML) can provide assistance for clinicians by obtaining and comprehensively preparing the history of patients, analysing face and voice and other clinical features, by integrating laboratory results, biomarkers, and imaging. Furthermore, AI/ML can provide a comprehensive risk assessment as a basis of optimal acute and chronic care. The clinical usefulness of AI/ML algorithms should be carefully assessed, validated with confirmation datasets before clinical use, and repeatedly re-evaluated as patient phenotypes change. This review provides an overview of the current data revolution that has changed and will continue to change the face of clinical medicine radically, if properly used, to the benefit of physicians and patients alike.

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Registry

Crossref · 10.1093/eurheartj/ehae465

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  • Generative AI models can analyze longitudinal data from patients with diabetes to predict cardiovascular events such as myocardial infarctions and strokes with greater accuracy than conventional risk assessment tools.

    “Generative AI model can analyze longitudinal data from patients with diabetes to predict cardiovascular events, such as myocardial infarctions and strokes, with greater accuracy than conventional risk assessment tools (100).”

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Authors
Lüscher, T. F., Wenzl, F. A., D’Ascenzo, F., Friedman, P. A., & Antoniades, C.
Affiliations
  • King's College London (GB)
  • National Health Service (GB)
  • Azienda Ospedaliera Citta' della Salute e della Scienza di Torino (IT)
  • Mayo Clinic (US)
  • University of Oxford (GB)
Corresponding author
Lüscher, Thomas F
Venue
European Heart Journal
Published
2024-08-19
Volume
45
Issue
40
Pages
4291-4304
ISSN
  • 0195-668X (ISSN-L)
  • 1522-9645
OpenAlex
W4401700474
Cited by
160
References
3
Citations by year
2026: 72 · 2025: 77 · 2024: 11
FWCI
3.64
Type
journal article
Language
en
Open access
Locations
  • European Heart Journal (publishedVersion)
  • PubMed (publishedVersion)
  • Zurich Open Repository and Archive (University of Zurich) (acceptedVersion, cc-by-nc-nd)
  • Institutional Research Information System University of Turin (University of Turin) (submittedVersion)
  • Zurich Open Repository and Archive (University of Zurich) (submittedVersion)
  • Zurich Open Repository and Archive (University of Zurich)
Topics
  • Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
  • Health Sciences › Health Professions › Health Information Management › Artificial Intelligence in Healthcare
  • Physical Sciences › Computer Science › Artificial Intelligence › Machine Learning in Healthcare
Keywords
artificial intelligence, machine learning, clinical decision support, risk assessment, biomarkers, algorithm validation, personalized medicine, clinical phenotype
MeSH terms
Clinical Decision-Making, Machine Learning, Artificial Intelligence, Cardiology, Cardiovascular Diseases, Humans, Risk Assessment

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