The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Focal uptake on 18F-fluoro-2-deoxyglucose positron emission tomography images indicates cardiac involvement of sarcoidosis†
Open accessAbstract
AIMS: To evaluate the value of (18)F-fluoro-2-deoxyglucose positron emission tomography ((18)F-FDG PET) in detecting cardiac sarcoidosis. METHODS AND RESULTS: Thirty-two patients with sarcoidosis and thirty controls were recruited. All subjects underwent cardiac (18)F-FDG PET after a 6 h fasting period, and subjects with sarcoidosis underwent blood testing, ECG, echocardiography, and (67)Ga and (99m)Tc-sestamibi (MIBI) scintigraphy. We classified (18)F-FDG PET images into four patterns ('none', 'diffuse', 'focal', and 'focal on diffuse') and found that all the control subjects exhibited either none (n=16) or diffuse (n=14) pattern. In contrast, fifteen subjects with sarcoidosis exhibited none, seven exhibited diffuse, eight exhibited focal, and two exhibited focal on diffuse patterns, with the prevalence of the focal and focal on diffuse patterns being significantly higher in the sarcoidosis group when compared with the control group (P<0.001). None of the 32 subjects with sarcoidosis exhibited abnormal findings on (67)Ga scintigraphy, and 4 exhibited abnormal findings on (99m)Tc-MIBI scintigraphy. CONCLUSION: Focal uptake of the heart on (18)F-FDG PET images is a characteristic feature of patients with sarcoidosis. Furthermore, (18)F-FDG PET has the potential to detect cardiac sarcoidosis that cannot be diagnosed by (67)Ga or (99m)Tc-MIBI scintigraphy.
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Cites
(1992) · PubMed Central · doi:10.2967/jnumed.120.251744a · Cited by 1,172
Roberts, W. C., McAllister, H. A., & Ferrans, V. J. (1977) · The American Journal of Medicine · doi:10.1016/0002-9343(77)90121-8 · Cited by 789
Cited by
Birnie, D. H., Nery, P. B., Ha, A. C., & Beanlands, R. S. B. (2016) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2016.03.605 · Cited by 569
Ohira, H., Tsujino, I., Ishimaru, S., Oyama, N., Takei, T., Tsukamoto, E., Miura, M., Sakaue, S., Tamaki, N., & Nishimura, M. (2008) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-007-0650-8 · Cited by 329
Self-citationKim, J. S., Judson, M. A., Donnino, R., Gold, M., Cooper, L. T., Prystowsky, E. N., & Prystowsky, S. (2009) · American Heart Journal · doi:10.1016/j.ahj.2008.09.009 · Cited by 328
The Clinical Features of Sarcoidosis: A Comprehensive Review
Judson, M. A. (2015) · Clinical Reviews in Allergy & Immunology · doi:10.1007/s12016-014-8450-y · Cited by 281
Cardiac sarcoidosis: state-of-the-art review
Kouranos, V., & Sharma, R. (2021) · Heart · doi:10.1136/heartjnl-2019-316442 · Cited by 259
Metadata
- Authors
- Ishimaru, S., Tsujino, I., Takei, T., Tsukamoto, E., Sakaue, S., Kamigaki, M., Ito, N., Ohira, H., Ikeda, D., Tamaki, N., & Nishimura, M.
- Venue
- European Heart Journal
- Publisher
- Oxford University Press (OUP)
- Published
- 2005-04-04
- Volume
- 26
- Issue
- 15
- Pages
- 1538-1543
- ISSN
- 0195-668X (ISSN-L)
- 1522-9645
- OpenAlex
- W2113455543
- Cited by
- 387
- References
- 2
- FWCI
- 6.20
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Ishimaru, S., Tsujino, I., Takei, T., Tsukamoto, E., Sakaue, S., Kamigaki, M., Ito, N., Ohira, H., Ikeda, D., Tamaki, N., & Nishimura, M. (2005). Focal uptake on 18F-fluoro-2-deoxyglucose positron emission tomography images indicates cardiac involvement of sarcoidosis†. European Heart Journal. https://doi.org/10.1093/eurheartj/ehi180
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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