The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Non-cardiac QTc-prolonging drugs and the risk of sudden cardiac death
Open accessAbstract
AIMS: To assess the association between the use of non-cardiac QTc-prolonging drugs and the risk of sudden cardiac death. METHODS AND RESULTS: A population-based case-control study was performed in the Integrated Primary Care Information (IPCI) project, a longitudinal observational database with complete medical records from more than 500,000 persons. All deaths between 1 January 1995 and 1 September 2003 were reviewed. Sudden cardiac death was classified based on the time between onset of cardiovascular symptoms and death. For each case, up to 10 random controls were matched for age, gender, date of sudden death, and general practice. The exposure of interest was the use of non-cardiac QTc-prolonging drugs. Exposure at the index date was categorized into three mutually exclusive groups of current use, past use, and non-use. The study population comprised 775 cases of sudden cardiac death and 6297 matched controls. Current use of any non-cardiac QTc-prolonging drug was associated with a significantly increased risk of sudden cardiac death (adjusted OR: 2.7; 95% CI: 1.6-4.7). The risk of death was highest in women and in recent starters. CONCLUSION: The use of non-cardiac QTc-prolonging drugs in a general population is associated with an increased risk of sudden cardiac death.
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Modeling and variable selection in epidemiologic analysis
Greenland, S. (1989) · American Journal of Public Health · doi:10.2105/ajph.79.3.340 · Cited by 2,208
Drug-induced prolongation of the QT interval
Roden, D. M. (2004) · New England Journal of Medicine · doi:10.1056/nejmra032426 · Cited by 1,965
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Antipsychotic Drug Use and Mortality in Older Adults with Dementia
Gill, S. S., Bronskill, S. E., Normand, S.-L. T., Anderson, G. M., Sykora, K., Lam, K., Bell, C. M., Lee, P. E., Fischer, H. D., Herrmann, N., et al. (2007) · Annals of Internal Medicine · doi:10.7326/0003-4819-146-11-200706050-00006 · Cited by 624
Schwartz, P. J., & Woosley, R. L. (2016) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2015.12.063 · Cited by 328
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Metadata
- Authors
- Straus, S. M. J. M., Sturkenboom, M. C. J. M., Bleumink, G. S., Dieleman, J. P., Lei, J. V. D., Graeff, P. A. D., Kingma, J. H., & Stricker, B. H. C.
- Venue
- European Heart Journal
- Publisher
- Oxford University Press (OUP)
- Published
- 2005-05-11
- Volume
- 26
- Issue
- 19
- Pages
- 2007-2012
- ISSN
- 0195-668X (ISSN-L)
- 1522-9645
- OpenAlex
- W2138784551
- Cited by
- 260
- References
- 2
- FWCI
- 8.49
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Straus, S. M. J. M., Sturkenboom, M. C. J. M., Bleumink, G. S., Dieleman, J. P., Lei, J. V. D., Graeff, P. A. D., Kingma, J. H., & Stricker, B. H. C. (2005). Non-cardiac QTc-prolonging drugs and the risk of sudden cardiac death. European Heart Journal. https://doi.org/10.1093/eurheartj/ehi312
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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