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Cited by 503

The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.

Catheter ablation treatment in patients with drug-refractory atrial fibrillation: a prospective, multi-centre, randomized, controlled study (Catheter Ablation For The Cure Of Atrial Fibrillation Study)†

Open access
Stabile, Giuseppe, Bertaglia, Emanuele, Senatore, Gaetano, De Simone, Antonio, Zoppo, Franco, Donnici, Giovanni, Turco, Pietro, Pascotto, Pietro, Fazzari, Massimo, Vitale, Dino Franco·2006·European Heart Journal

Abstract

AIMS: We conducted a multi-centre, prospective, controlled, randomized trial to investigate the adjunctive role of ablation therapy to antiarrhythmic drug therapy in preventing atrial fibrillation (AF) relapses in patients with paroxysmal or persistent AF in whom antiarrhythmic drug therapy had already failed. METHODS AND RESULTS: One hundred and thirty seven patients were randomized to ablation and antiarrhythmic drug therapy (ablation group) or antiarrhythmic drug therapy alone (control group). In the ablation group, patients underwent cavo-tricuspid and left inferior pulmonary vein (PV)-mitral isthmus ablation plus circumferential PV ablation. The primary end-point of the study was the absence of any recurrence of atrial arrhythmia lasting >30 s in the 1-year follow-up period, after 1-month blanking period. Three (4.4%) major complications were related to ablation: one patient had a stroke during left atrium ablation, another suffered transient phrenic paralysis, and the third had a pericardial effusion which required pericardiocentesis. After 12 months of follow-up, 63/69 (91.3%) control group patients had at least one AF recurrence, whereas 30/68 (44.1%) (P<0.001) ablation group patients had atrial arrhythmia recurrence (four patients had atrial flutter, 26 patients AF). CONCLUSION: Ablation therapy combined with antiarrhythmic drug therapy is superior to antiarrhythmic drug therapy alone in preventing atrial arrhythmia recurrences in patients with paroxysmal or persistent AF in whom antiarrhythmic drug therapy has already failed.

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Registry

Crossref · 10.1093/eurheartj/ehi583

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Metadata

Authors
Stabile, G., Bertaglia, E., Senatore, G., De Simone, A., Zoppo, F., Donnici, G., Turco, P., Pascotto, P., Fazzari, M., & Vitale, D. F.
Venue
European Heart Journal
Published
2005-10-07
Volume
27
Issue
2
Pages
216-221
ISSN
  • 0195-668X (ISSN-L)
  • 1522-9645
OpenAlex
W2163947034
Cited by
503
References
26
FWCI
16.33
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Catheter ablation treatment in patients with drug-refractory atrial fibrillation: a prospective, multi-centre, randomized, controlled study (Catheter Ablation For The Cure Of Atrial Fibrillation Study)†. https://app.cochat.ai/papers/10.1093/eurheartj/ehi583
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Stabile, G., Bertaglia, E., Senatore, G., De Simone, A., Zoppo, F., Donnici, G., Turco, P., Pascotto, P., Fazzari, M., & Vitale, D. F. (2006). Catheter ablation treatment in patients with drug-refractory atrial fibrillation: a prospective, multi-centre, randomized, controlled study (Catheter Ablation For The Cure Of Atrial Fibrillation Study)†. European Heart Journal. https://doi.org/10.1093/eurheartj/ehi583

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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